Article
Multidisciplinary Sciences
Joan Forns, J. Bradley Layton, Jennifer Bartsch, Mary Ellen Turner, Colleen Dempsey, Mary Anthony, Mary E. Ritchey, George Demos
Summary: The study evaluated the risk of falls and fractures in patients with Parkinson disease with psychosis (PDP) compared to those without psychosis at similar disease stages. The results showed that PDP patients had a slightly higher risk of falls and fractures, particularly in falls, compared to PD patients without psychosis.
Article
Chemistry, Analytical
Hayslenne A. G. O. Araujo, Suhaila M. Smaili, Rosie Morris, Lisa Graham, Julia Das, Claire McDonald, Richard Walker, Samuel Stuart, Rodrigo Vitorio
Summary: Although the multifactorial nature of falls in Parkinson's disease (PD) is well described, optimal assessment for the identification of fallers remains unclear. Thus, we aimed to identify clinical and objective gait measures that best discriminate fallers from non-fallers in PD, with suggestions of optimal cutoff scores.
Article
Neurosciences
Andrew S. Monaghan, Andrew Hooyman, Leland E. Dibble, Shyamal H. Mehta, Daniel S. Peterson
Summary: This study aimed to examine whether cognition could predict the responsiveness of people with Parkinson's Disease (PwPD) to reactive step training. The results showed that PwPD with higher baseline global cognition retained better improvements in stepping after a two-month intervention. These findings highlight the potential of cognitive screening to identify which individuals with Parkinson's Disease are more likely to benefit from reactive balance training.
NEUROSCIENCE LETTERS
(2023)
Review
Health Care Sciences & Services
Cosimo Tuena, Francesca Borghesi, Francesca Bruni, Silvia Cavedoni, Sara Maestri, Giuseppe Riva, Mauro Tettamanti, Rosa Liperoti, Lorena Rossi, Maurizio Ferrarin, Marco Stramba-Badiale
Summary: Cognitive-motor dual-task (CMDT) is essential in daily life and can be challenging for older adults with chronic age-related conditions. Technology-assisted CMDT rehabilitation has shown to be effective in improving motor-cognitive functions, particularly for dual-task performances, falls, gait, and cognition. However, further research is needed to explore its application in different chronic conditions and frailty status.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Cardiac & Cardiovascular Systems
Cristino C. Oliveira, Raquel Annoni, Annemarie L. Lee, Jennifer McGinley, Louis B. Irving, Linda Denehy
Summary: This systematic review synthesized falls outcomes in COPD patients, finding a 30% prevalence of fallers and a 24% prevalence of frequent fallers. Risk factors for falls in stable COPD include age, female gender, falls history, number of medications, comorbidities, coronary heart disease, use of supplemental oxygen, impaired balance performance, and smoking history. Further research with prospective recording is needed in COPD.
RESPIRATORY MEDICINE
(2021)
Article
Orthopedics
Marco Godi, Ilaria Arcolin, Breiffni Leavy, Marica Giardini, Stefano Corna, Erika Franzen
Summary: The original unidimensional Mini-BESTest model with a total score of 28 showed the highest validity and reliability and was best at discriminating fallers from nonfallers. However, its 4 subsections should not be reported separately, because they were highly correlated and had low reliability.
Review
Nursing
Orawan Kuljeerung, Helen W. Lach
Summary: Falls in older adults with Parkinson's disease commonly happen indoors and outdoors during daily activities in familiar home environments and out in the community. Common challenges include uneven environments and risky behavior like hurrying.
REHABILITATION NURSING
(2021)
Article
Clinical Neurology
Daniele Belvisi, Roberta Pellicciari, Andrea Fabbrini, Matteo Costanzo, Gaia Ressa, Sara Pietracupa, Maria De Lucia, Nicola Modugno, Francesca Magrinelli, Carlo Dallocchio, Tommaso Ercoli, Alessandra Nicoletti, Mario Zappia, Paolo Solla, Matteo Bologna, Giovanni Fabbrini, Michele Tinazzi, Antonella Conte, Alfredo Berardelli, Giovanni Defazio
Summary: This multicenter study aimed to investigate the relationship between risk factors and clinical motor and non-motor features in Parkinson's disease (PD) patients. The results showed that coffee consumption was associated with older age at onset and milder motor symptom severity. Patients with dyspepsia before PD had more severe non-motor symptoms, while patients who performed physical activity before PD had milder non-motor symptoms.
PARKINSONISM & RELATED DISORDERS
(2022)
Review
Biochemistry & Molecular Biology
Melania Melis, Antje Haehner, Mariano Mastinu, Thomas Hummel, Iole Tomassini Barbarossa
Summary: Impairments in olfaction and taste are common non-motor symptoms in Parkinson's disease, often appearing before motor symptoms onset. The basis for these dysfunctions are likely multifactorial, potentially sharing determinants with other non-motor symptoms of PD. Associations with the microbiota may also represent risk factors associated with the disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Immunology
Rachel J. Boyd, Dimitri Avramopoulos, Lauren L. Jantzie, Andrew S. McCallion
Summary: Multifactorial diseases pose a challenge in understanding the interactions between genetic and environmental factors, particularly in neurodegenerative disorders. The focus of research is on how genetic and environmental effects destabilize homeostasis and increase risk, as well as finding effective therapeutic interventions.
JOURNAL OF NEUROINFLAMMATION
(2022)
Article
Rehabilitation
G. Alagumoorthi, Beulah D. Jebakani, Suresh Thirunavukarasu, V Ramachandaran, V Kumaresan
Summary: The objective of this study is to assess the effectiveness of Wii sports-based strategy training in reducing the risk of falling, number of falls, and improving quality of life in adults with idiopathic Parkinson's disease. The study found that a 12-week Wii training program can decrease the risk of falling and number of falls in Parkinson's disease patients, but did not alter their quality of life.
CLINICAL REHABILITATION
(2022)
Article
Medicine, General & Internal
Yosuke Nakadate, Daiki Nakashige, Keiko Omori, Takashi Matsukawa
Summary: Surgical treatment for Parkinson disease (PD) patients under general anesthesia is common, but the factors predicting complications in these patients are unclear. A retrospective study of PD patients who underwent surgery between April 2015 and March 2019 found that the prevalence of postoperative complications was 28%. Risk factors for complications included longer operation time and preoperative use of the dopamine agonist rotigotine. Close monitoring of postoperative complications is necessary in PD patients who have received transdermal dopamine agonists and undergone longer surgeries.
Article
Clinical Neurology
L. A. King, P. Carlson-Kuhta, J. L. Wilhelm, J. A. Lapidus, M. L. Dale, L. S. Talman, N. Barlow, M. Mancini, F. B. Horak
Summary: This study aims to explore the effects of rehabilitation on turning ability in Parkinson's disease (PD) patients. Sixty PD patients with a history of falls will be randomly assigned to receive a turning intervention or no intervention. Wearable sensors will be used to measure turning quality, and blinded assessments will be conducted to evaluate gait, mobility, and turns. Falls will be monitored for twelve months post intervention through email questionnaires. This study has the potential to change the rehabilitation and assessment of turning in PD patients and may improve daily turning ability and reduce falls.
Article
Clinical Neurology
Christopher Kobylecki, Irena Shiderova, Mihaela Boca, Emilia Michou
Summary: The severity of dysphagia in PD is closely related to the severity of falls, but not to gait freezing. This finding may help to pinpoint the anatomical substrate of levodopa-resistant axial symptoms in PD and provide insights for further management.
NEUROLOGICAL SCIENCES
(2022)
Letter
Clinical Neurology
Tomoyuki Kawada
Summary: The study revealed that high baseline dietary antioxidants such as vitamin E and vitamin C were inversely associated with Parkinson's disease, while there was no significant association between estimated intake of dietary beta-carotene or NEAC and Parkinson's disease.
Article
Clinical Neurology
Elzbieta Mirek, Magdalena Filip, Wieslaw Chwala, Jadwiga Szymura, Szymon Pasiut, Krzysztof Banaszkiewicz, Monika Rudzinska Bar, Andrzej Szczudlik
NEUROLOGIA I NEUROCHIRURGIA POLSKA
(2018)
Article
Sport Sciences
R. Walaszek, S. Sterkowicz, W. Chwala, K. Sterkowicz-Przybycien, K. Burdacka, M. Burdacki
Article
Clinical Neurology
Joanna Siuda, Magdalena Boczarska-Jedynak, Slawomir Budrewicz, Jaroslaw Dulski, Monika Figura, Urszula Fiszer, Agata Gajos, Agnieszka Gorzkowska, Ewa Koziorowska-Gawron, Dariusz Koziorowski, Anna Krygowska-Wajs, Monika Rudzinska-Bar, Jaroslaw Slawek, Xuehan Ren, Sheng Luo, Pablo Martinez-Martin, Glenn Stebbins, Christopher G. Goetz, Grzegorz Opala, Andrzej Bogucki, Piotr Janik, Magdalena Koszewicz, Marta Lenska-Mieciek, Malgorzata Michalowska, Marta Piascik-Gromada, Katarzyna Potasz-Kulikowska, Marek Smilowski, Anna Wasielewska, Magdalena Wojcik-Pedziwiatr
NEUROLOGIA I NEUROCHIRURGIA POLSKA
(2020)
Article
Audiology & Speech-Language Pathology
Daria Hemmerling, Magdalena Wojcik-Pedziwiatr
Summary: This paper explores the potential of using speech signal processing and regression methods to assess the neurological state of Parkinson's disease patients after medication. By analyzing recordings of 27 patients' vowel sounds, a software was developed to predict acoustic parameters and evaluate Parkinson's disease ratings. The results demonstrate the software's ability to support clinicians in therapy monitoring and provide quantitative assessment of treatment results.
Article
Clinical Neurology
Joanna Siuda, Magdalena Boczarska-Jedynak, Slawomir Budrewicz, Jaroslaw Dulski, Monika Figura, Urszula Fiszer, Agata Gajos, Agnieszka Gorzkowska, Ewa Koziorowska-Gawron, Dariusz Koziorowski, Anna Krygowska-Wajs, Monika Rudzinska-Bar, Jaroslaw Slawek, Mateusz Tos, Magdalena Wojcik-Pedziwiatr, Jeffrey Lin, Sheng Luo, Pablo Martinez-Martin, Glenn T. Stebbins, Christopher G. Goetz, Grzegorz Opala
Summary: The study validated the Polish translation of the UDysRS and found that it shared a consistent factor structure with the Reference Standard Spanish version. The Official Polish UDysRS translation is recommended for use in clinical and research settings, providing a common ground for studying disease manifestations and progression across cultures.
NEUROLOGIA I NEUROCHIRURGIA POLSKA
(2021)
Article
Clinical Neurology
Katarzyna Sawczynska, Marcin Wnuk, Jeremiasz Jagiella, Tomasz Kesek, Magdalena Wolska-Sikora, Magdalena Szara-Cichon, Kinga Zagata-Szewczyk, Adela Uchacz, Katarzyna Filipowicz, Marcin Plaszczak, Katarzyna Spisak-Borowska, Anna Baranowska, Magdalena Wojcik-Pedziwiatr, Marta Swarowska-Skuza, Elzbieta Szczygiel-Pilut, Mariusz Klos, Piotr Grzyb, Michal Biela, Joanna Mierzwinska, Iwona Sinkiewicz, Jerzy Machowski, Anna Wegrzyn, Michal Michalski, Ryszard Nowak, Agnieszka Slowik
Summary: The 4C Mortality Score can predict the functional outcome at discharge in COVID-19-associated AIS patients, as it correlates with the modified Rankin Scale (mRS) at discharge. Additionally, there is a statistically significant difference in the mean 4C Mortality Score between patients who died and patients who survived the stroke.
NEUROLOGIA I NEUROCHIRURGIA POLSKA
(2021)
Article
Medicine, General & Internal
Klaudia Plinta, Andrzej Plewka, Magdalena Wojcik-Pedziwiatr, Nikola Zmarzly, Marcin Rudzinski, Monika Rudzinska-Bar
Summary: This study evaluated the use of plasma TGF-beta 1 levels in assessing Huntington's disease severity, and found that it is not suitable as a marker of the disease.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Nutrition & Dietetics
Barbara Zapala, Tomasz Stefura, Tomasz Milewicz, Julia Wator, Monika Piwowar, Magdalena Wojcik-Pedziwiatr, Magdalena Doregowska, Alicja Dudek, Zuzanna Jania, Monika Rudzinska-Bar
Summary: The type of diet is associated with an increased risk of Parkinson's disease and affects the composition of oral microflora. This study compared the diet preferences and oral microbiota profiles of patients with PD and healthy controls, and found differences in oral microbiota composition and specific bacteria abundance between the two groups. There were also differences in food preferences, with patients with PD having higher intake of certain foods compared to healthy controls.
Article
Medicine, General & Internal
Klaudia Plinta, Andrzej Plewka, Krzysztof Pawlicki, Nikola Zmarzly, Magdalena Wojcik-Pedziwiatr, Marcin Rudzinski, Agnieszka Krzak-Kubica, Magdalena Doregowska-Stachera, Monika Rudzinska-Bar
Summary: The study explored the relationship between plasma BDNF concentration and HD severity, finding that BDNF levels were inversely correlated with different stages of HD, but were not related to motor symptoms or cognitive impairment.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Barbara Zapala, Tomasz Stefura, Magdalena Wojcik-Pedziwiatr, Radoslaw Kabut, Marta Balajewicz-Nowak, Tomasz Milewicz, Alicja Dudek, Anastazja Stoj, Monika Rudzinska-Bar
Summary: The study compared the gut microbiota composition between patients diagnosed with Parkinson's disease and those treated only with Levodopa to healthy controls, finding that PD patients have significantly different gut microbiota profiles.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Health Care Sciences & Services
Szymon Podsiadlo, Agnieszka Skiba, Anna Kaluza, Bartlomiej Ptaszek, Joanna Stozek, Amadeusz Skiba, Anna Marchewka
Summary: The study showed that a 12-week Nordic walking training intervention had a positive impact on the quality of life and vitamin D levels among women aged 65-74, particularly in terms of physical and mental health components.
Article
Biophysics
Stanislaw Sterkowicz, Grzegorz Lech, Katarzyna Sterkowicz-Przybycien, Wieslaw Chwala, Tadeusz Ambrozy, Tomasz Palka
ACTA OF BIOENGINEERING AND BIOMECHANICS
(2018)
Article
Biophysics
Katarzyna Ogrodzka-Ciechanowicz, Dorota Czechowska, Wieslaw Chwala, Jakub Slusarski, Artur Gadek
ACTA OF BIOENGINEERING AND BIOMECHANICS
(2018)
Article
Neurosciences
Paul McNulty, Richard Pilcher, Raviram Ramesh, Renata Necuiniate, Alis Hughes, Daniel Farewell, Peter Holmans, Lesley Jones
JOURNAL OF HUNTINGTONS DISEASE
(2018)