Article
Neurosciences
Jose Maria Martinez de Paz, Emilie Mace
Summary: Functional ultrasound (fUS) is a hemodynamic-based neuroimaging technique with high spatiotemporal resolution, large field of view, and compatibility with behavior, making it well-suited for studying patterns of correlated activity between brain regions and brain-wide pathways associated with behavior. By combining fUS with optogenetics, its capabilities can be further enhanced, promising a significant impact in multi-modal studies.
Article
Neurosciences
Julie Sato, Kristina Safar, Marlee M. Vandewouw, Nicole Bando, Deborah L. O'Connor, Sharon L. Unger, Margot J. Taylor
Summary: The study found atypical recruitment of emotional face processing networks in theta band in children born with very low birth weight, especially with reduced connectivity during processing of angry faces. Despite performing within the normal range behaviorally, this selective impairment in processing angry faces may negatively impact social functioning in preterm children. Additionally, greater recruitment of this theta-band network in full-term children was associated with improved affect recognition scores, suggesting an important role of theta oscillations in early face processing.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2021)
Article
Neurosciences
Stefania Benetti, Ambra Ferrari, Francesco Pavani
Summary: In face-to-face communication, humans need to interpret multiple layers of discontinuous multimodal signals as coherent and unified communicative actions. This poses a computational challenge of binding relevant signals together while segregating unrelated signals. To address this, a neurocognitive model is proposed by combining psycholinguistic and sensory neuroscience frameworks. The model suggests the implementation of multiplex signals, multimodal gestalts, and multilevel predictions along a lateral processing pathway. A multimodal and multidisciplinary research approach is advocated for further empirical testing.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Psychiatry
Tiana Borgers, Marla Kuerten, Anna Kappelhoff, Verena Enneking, Anne Mollmann, Johanna Schulte, Melissa Klug, Elisabeth J. Leehr, Katharina Dohm, Dominik Grotegerd, Philine Krause, Esther Zwiky, Udo Dannlowski, Ulrike Buhlmann, Ronny Redlich
Summary: Individuals with BDD exhibit aberrant functional activity and connectivity patterns within the amygdala and FFG during negative emotional face processing, while body dysmorphic symptoms in HC are associated with brain functional alterations.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychology, Multidisciplinary
Phoebe Chen, Ulrich Kirk, Suzanne Dikker
Summary: In recent years, mindfulness meditation has gained much interest, but there is limited neurobiological evidence on the prosocial benefits of mindfulness in social settings. This study used intra-brain and inter-brain measures to investigate the relationship between trait mindful awareness and social interaction.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Clinical Neurology
Linling Li, Xue Han, Erni Ji, Xiangrong Tao, Manjun Shen, Dongjian Zhu, Li Zhang, Lingjiang Li, Haichen Yang, Zhiguo Zhang
Summary: This study analyzed functional MRI data of bipolar disorder (BD) patients and healthy controls during a face-matching task and found widely distributed aberrant task-modulated functional connectivity (FC) patterns in BD. The fronto-parietal network was identified as the primary network demonstrating changes in both FC strength and local efficiency in BD.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Neurosciences
Roni Setton, Laetitia Mwilambwe-Tshilobo, Manesh Girn, Amber W. Lockrow, Giulia Baracchini, Colleen Hughes, Alexander J. Lowe, Benjamin N. Cassidy, Jian Li, Wen-Ming Luh, Danilo Bzdok, Richard M. Leahy, Tian Ge, Daniel S. Margulies, Bratislav Misic, Boris C. Bernhardt, W. Dale Stevens, Felipe De Brigard, Prantik Kundu, Gary R. Turner, R. Nathan Spreng
Summary: The functional organization of the brain changes with age, with observed differences at multiple spatial scales. Older adults show global network dedifferentiation and network-specific patterns of dedifferentiation, suggesting changes in brain function with age.
Article
Psychology, Multidisciplinary
Antonella Tramacere
Summary: This article investigates the effect of mirror gazing on self-perception and argues that our feelings towards others can influence our responses to our own mirror image, thus creating a vicious cycle.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Neurosciences
Michael W. Cole, Takuya Ito, Carrisa Cocuzza, Ruben Sanchez-Romero
Summary: Resting-state functional connectivity provides insights into brain network organization, but the functional importance of task-related changes remains unclear. Task-state functional connectivity can predict cognitive task activations better, driven by individual-specific functional connectivity patterns. These findings suggest task-related changes play a role in reshaping brain network organization and altering neural activity flow during task performance.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Michela Balconi, Giulia Fronda, Federico Cassioli, Davide Crivelli
Summary: The digitalization process for organizations, accelerated by the COVID-19 pandemic, presents challenges for Human Resource Management (HRM). This study aims to investigate the impact of face-to-face (FTF) and remote computer-mediated (RCM) interaction settings on assessment interviews. A neuroscientific protocol will be used to collect various metrics from both inter-agents and examine the perceived quality of interaction, visual-attentional patterns, cognitive workload, and emotional engagement. The findings will contribute to understanding the differences between FTF and RCM settings in complex social interactions, particularly job interviews.
Article
Multidisciplinary Sciences
Xingyu Liu, Yuxuan Dai, Hailun Xie, Zonglei Zhen
Summary: Naturalistic stimuli, such as movies, are increasingly used to study brain function. This study presents the first public prolonged MEG dataset to observe the neural dynamics of participants while watching a movie, providing a foundation for exploring cognitive functions in real-world contexts.
Article
Psychiatry
Lei Lei, Yu Zhang, Xiaotong Song, Penghong Liu, Yujiao Wen, Aixia Zhang, Chunxia Yang, Ning Sun, Zhifen Liu, Kerang Zhang
Summary: This study investigated whether patients with major depressive disorder develop facial perceptual processing disorders with characteristics of brain functional connectivity. The findings revealed that MDD patients had lower face recognition amplitudes and stronger functional connectivity in several brain regions compared to healthy controls.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Behavioral Sciences
Robert S. Chavez, Dale T. Tovar, Moriah S. Stendel, Taylor D. Guthrie
Summary: This study aimed to generalize the relationship between self-esteem and frontostriatal connectivity by using an out-of-sample predictive modeling approach on a larger independent sample. The results showed a significant predictive power of frontostriatal integrity on self-esteem in the independent dataset, indicating the robustness of these findings across different scanning acquisition, analytic methods, and participant demographics.
Article
Neurosciences
Christopher J. Hyatt, Bruce E. Wexler, Brian Pittman, Alycia Nicholson, Godfrey D. Pearlson, Silvia Corbera, Morris D. Bell, Kevin Pelphrey, Vince D. Calhoun, Michal Assaf
Summary: Autism spectrum disorder (ASD), schizophrenia (SZ), and typically developed (TD) individuals were compared in their engagement in dynamic functional network connectivity (dFNC) states during social-emotional processing. Results showed differences in neural processing of emotions between ASD and TD, with ASD spending more time in a sad-associated state compared to TD individuals. This highlights the importance of examining whole-brain reconfiguration of FNC to understand unique emotion-specific dFNC states.
Article
Engineering, Biomedical
Kevin C. Davis, Benyamin Meschede-Krasa, Iahn Cajigas, Noeline W. Prins, Charles Alver, Sebastian Gallo, Shovan Bhatia, John H. Abel, Jasim A. Naeem, Letitia Fisher, Fouzia Raza, Wesley R. Rifai, Matthew Morrison, Michael E. Ivan, Emery N. Brown, Jonathan R. Jagid, Abhishek Prasad
Summary: This study developed a portable and modular brain-computer interface (BCI) software platform independent of input and output devices, which was successfully implemented in a case study of a subject with cervical spinal cord injury.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2022)
Article
Biochemical Research Methods
Hamed Ekhtiari, Mehran Zare-Bidoky, Arshiya Sangchooli, Amy C. Janes, Marc J. Kaufman, Jason A. Oliver, James J. Prisciandaro, Torsten Wustenberg, Raymond F. Anton, Patrick Bach, Alex Baldacchino, Anne Beck, James M. Bjork, Judson Brewer, Anna Rose Childress, Eric D. Claus, Kelly E. Courtney, Mohsen Ebrahimi, Francesca M. Filbey, Dara G. Ghahremani, Peyman Ghobadi Azbari, Rita Z. Goldstein, Anna E. Goudriaan, Erica N. Grodin, J. Paul Hamilton, Colleen A. Hanlon, Peyman Hassani-Abharian, Andreas Heinz, Jane E. Joseph, Falk Kiefer, Arash Khojasteh Zonoozi, Hedy Kober, Rayus Kuplicki, Qiang Li, Edythe D. London, Joseph McClernon, Hamid R. Noori, Max M. Owens, Martin Paulus, Irene Perini, Marc Potenza, Stephane Potvin, Lara Ray, Joseph P. Schacht, Dongju Seo, Rajita Sinha, Michael N. Smolka, Rainer Spanagel, Vaughn R. Steele, Elliot A. Stein, Sabine Steins-Loeber, Susan F. Tapert, Antonio Verdejo-Garcia, Sabine Vollstaedt-Klein, Reagan R. Wetherill, Stephen J. Wilson, Katie Witkiewitz, Kai Yuan, Xiaochu Zhang, Anna Zilverstand
Summary: This study established parameters and reporting standards for cue reactivity research in functional magnetic resonance imaging, and conducted a review on relevant published studies, revealing gaps in the reporting of important items.
Article
Clinical Neurology
Kathleen Crum, Julianne C. Flanagan, Brandon Vaughan, Joseph Aloi, Megan M. Moran-Santa Maria, Sudie E. Back, Kathleen T. Brady, Jane E. Joseph
Summary: Childhood maltreatment is associated with PTSD in adulthood, with oxytocin potentially helping to ameliorate attentional neurocircuitry dysfunction in individuals with PTSD and maltreatment histories. The study also found reduced connectivity between attention networks in individuals with PTSD and a history of sexual abuse.
PSYCHIATRY RESEARCH-NEUROIMAGING
(2021)
Article
Clinical Neurology
Lauren M. Sippel, Julianne C. Flanagan, Paul E. Holtzheimer, Megan M. Moran-Santa-Maria, Kathleen T. Brady, Jane E. Joseph
Summary: The study found that intranasal oxytocin modulates threat salience among childhood trauma-exposed individuals, and these effects vary as a function of gender and hemisphere.
PSYCHIATRY RESEARCH-NEUROIMAGING
(2021)
Editorial Material
Clinical Neurology
John E. McGeary, McKenzie J. Quinn, Caitlyn N. Starr, Matthew Borgia, Chelsie E. Benca-Bachman, Jamie L. Catalano, Noah S. Philip
Article
Neurosciences
Alexander S. Hatoum, Claire L. Morrison, Evann C. Mitchell, Max Lam, Chelsie E. Benca-Bachman, Andrew E. Reineberg, Rohan H. C. Palmer, Luke M. Evans, Matthew C. Keller, Naomi P. Friedman
Summary: This study found that deficits in executive functions are associated with psychopathology and neurologic disorders, and there is a genetic correlation with measures of intelligence and cognitive processing speed. The results suggest that executive functions are genetically distinct cognitive constructs that are particularly relevant to understanding genetic variance in psychiatric disorders.
BIOLOGICAL PSYCHIATRY
(2023)
Article
Endocrinology & Metabolism
Adriene M. Beltz, Michael I. Demidenko, Natasha Chaku, Kelly L. Klump, Jane E. Joseph
Summary: Intrauterine devices (IUDs), the most-used reversible contraceptive method, have potential effects on brain function, cognition, and behavior that are currently not well understood. This paper explores the importance of studying IUD use through neuroimaging, network analyses, and person-specific approaches to advance our knowledge of the interplay between exogenous and endogenous sex hormones. The findings illustrate the feasibility and utility of studying IUD users as a natural experiment to enhance our understanding of basic neuroendocrinology and women's health.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, Research & Experimental
Sudie E. Back, Julianne C. Flanagan, Therese Killeen, Tanya C. Saraiya, Delisa G. Brown, Amber M. Jarnecke, Alex O. Rothbaum, Jane Joseph, Elizabeth Santa Ana, Abigail de Arellano, Hannah L. Shoemaker, Reagan Ashley Dixon, Paul J. Nietert, Kathleen T. Brady
Summary: This study aims to investigate the synergistic effects of a novel pharmacotherapy and psychotherapy for individuals with co-occurring alcohol use disorder and posttraumatic stress disorder. The study will examine the effects of treatment on corticolimbic connectivity using functional magnetic resonance imaging, and may lead to improved treatment outcomes for individuals with this comorbidity.
CONTEMPORARY CLINICAL TRIALS
(2023)
Article
Developmental Biology
Christopher T. Sege, Lisa M. McTeague, Molly Kegley, Curtisha Shacklewood, Colleen A. Halliday, Casey D. Calhoun, Jane E. Joseph, Zachary W. Adams, Greg Hajcak, Carla Kmett Danielson
Summary: This article examines potential changes in the processing of predictable events during the childhood-to-adolescence transition. The study finds that children show enhanced processing of predicted scary content, but unlike adults, they show reduced anticipatory processing of scary images in predictable contexts.
DEVELOPMENTAL PSYCHOBIOLOGY
(2023)
Article
Developmental Biology
Christopher T. Sege, Lisa M. McTeague, Molly Kegley, Curtisha Shacklewood, Colleen A. Halliday, Casey D. Calhoun, Jane E. Joseph, Zachary W. Adams, Greg Hajcak, Carla Kmett Danielson
Summary: This article examines the regulation of emotional response and attention modulation during the processing of predictable unpleasant events in children and adolescents. The study found that blink reflexes and brain event-related potentials (ERPs) were increased during aversive anticipation, but decreased after the predictable aversive event occurred. These findings suggest that individuals have the ability to downregulate defensive priming and maintain attentional modulation once the awaited aversive event happens, even in pre-adolescents.
DEVELOPMENTAL PSYCHOBIOLOGY
(2023)
Article
Psychology, Clinical
Sudie E. Back, Julianne C. Flanagan, Jim Mintz, Kathleen T. Brady, Jennifer Jones, Amber M. Jarnecke, Jane E. Joseph, David W. Shirley, Robert J. Malcolm, Mark Hamner, Brett T. Litz, Barbara L. Niles, Stacey Young-McCaughan, Terence M. Keane, Alan L. Peterson, Consortium Alleviate PTSD
Summary: The aim of this study was to determine the efficacy of doxazosin for the treatment of co-occurring PTSD and AUD. The results showed that doxazosin was safe and tolerable but not more effective than placebo in reducing the severity of PTSD or AUD.
JOURNAL OF CLINICAL PSYCHIATRY
(2023)
Article
Education & Educational Research
Caroline Catherman, Samantha Cassidy, Chelsie E. Benca-Bachman, Jessica M. Barber, Rohan H. C. Palmer
Summary: Neuroticism has a direct impact on depressive symptoms and sleep quality of college freshmen. Poor sleep quality is associated with depressive symptoms, and there are prospective associations between sleep quality and depression symptoms at different time points throughout the first year of college.
JOURNAL OF AMERICAN COLLEGE HEALTH
(2023)
Article
Neurosciences
Ashley A. Huggins, Lisa M. McTeague, Megan M. Davis, Nicholas Bustos, Kathleen I. Crum, Rachel Polcyn, Zachary W. Adams, Laura A. Carpenter, Greg Hajcak, Colleen A. Halliday, Jane E. Joseph, Carla Kmett Danielson
Summary: Childhood socioeconomic disadvantage may affect how the brain perceives and responds to potential threats. Future longitudinal studies are crucial for understanding how these effects persist throughout the lifespan and how health outcomes can be improved through community interventions and policies.
BIOLOGICAL PSYCHIATRY: GLOBAL OPEN SCIENCE
(2022)
Article
Substance Abuse
Victoria A. Risner, Chelsie E. Benca-Bachman, Lauren Bertin, Alicia K. Smith, Jaakko Kaprio, John E. McGeary, Elissa Chesler, Valerie S. Knopik, Naomi P. Friedman, Rohan H. C. Palmer
Summary: The study found that the risk for nicotine dependence is not only polygenic, but also pleiotropic. Polygenic effects accessible by educational attainment, cigarettes per day, and self-perceived risk-taking were the most robust predictors, with limited effects on nicotine dependence explained by polygenic scores.
NICOTINE & TOBACCO RESEARCH
(2021)
Article
Psychology, Developmental
Lauren Micalizzi, Leslie A. Brick, Marisa E. Marraccini, Chelsie E. Benca-Bachman, Rohan H. C. Palmer, Valerie S. Knopik
Summary: The study investigated the genetic overlap between inattention and various aspects of neurocognitive efficiency, revealing specificity in this genetic overlap among different aspects of cognitive functioning.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2021)
Article
Health Care Sciences & Services
Daniel R. Baer, Andrew B. Lawson, Jane E. Joseph
Summary: To better identify the risk of Alzheimer's disease, this study developed Bayesian hierarchical models through space-time modeling of Alzheimer's disease incidence data. By borrowing risk information from antecedent conditions, such as mild cognitive impairment, the models showed improved goodness of fit and highlighted the importance of diagnosing label-switching problems and model specification for accurately capturing the contribution of time in modeling Alzheimer's disease risk.
STATISTICAL METHODS IN MEDICAL RESEARCH
(2021)
