Article
Psychology, Multidisciplinary
Maire B. Ford
Summary: This study examines the impact of implicit theories on social threat. The results show that individuals with an incremental theory are better equipped to protect their social self-esteem, reduce rumination, and minimize concerns about their social skills compared to those with an entity theory when facing social-evaluative threat.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Biology
Joana B. Vieira, Andreas Olsson
Summary: Empathy for others' distress has long been considered important for helping, but self-defense also plays a role in helping behavior. This study used fMRI to examine the involvement of human defensive neural circuits in helping decisions. The results showed that participants who were more engaged with neural circuits involved in escaping self-directed danger were more likely to help others. Specifically, the activation of the amygdala and insula, which represented the threat to oneself rather than the other's distress, predicted helping behavior.
Article
Biology
Lihua Sun, Lasse Lukkarinen, Vesa Putkinen, Henry K. Karlsson, Jussi Hirvonen, Jari Tiihonen, Hannu Lauerma, Sophie Scott, Lauri Nummenmaa
Summary: Laughter and crying, as social signals, evoke different brain responses modulated by the central MOR system. Our findings highlight the role of the MOR system in modulating acute brain responses to both positive and negative social signals.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Psychology, Multidisciplinary
Sarah M. Tashjian, Virginia Fedrigo, Tanaz Molapour, Dean Mobbs, Colin F. Camerer
Summary: This study reveals the significance of social dynamics (friends vs. strangers) on tonic arousal and the impact of subjective fear and threat predictability on phasic arousal.
PSYCHOLOGICAL SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Yafeng Pan, Mikkel C. Vinding, Lei Zhang, Daniel Lundqvist, Andreas Olsson
Summary: The study finds that observing others' defensive behaviors is crucial for learning about dangers. The specific neural mechanisms responsible for integrating information between demonstrators and observers are unknown. The study reveals brain-to-brain coupling (BtBC) within demonstrator-observer dyads, which predicts learning expressions and is stronger when threats are imminent. The coupling also depends on observers' perception of social status and is driven by shared attention and emotion.
Article
Multidisciplinary Sciences
Adi Ulmer Yaniv, Roy Salomon, Shani Waidergoren, Ortal Shimon-Raz, Amir Djalovski, Ruth Feldman
Summary: The study reveals the importance of synchronous caregiving in tuning the human social brain, particularly in regions involved in salience detection, interoception, and mentalization. Maternal-newborn contact enhances social synchrony, which in turn predicts the brain's sensitivity to emotion-specific empathy, linking with greater empathic understanding in adolescence and higher neural sensitivity to emotion-specific empathy in adulthood.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Adi Ulmer Yaniv, Roy Salomon, Shani Waidergoren, Ortal Shimon-Raz, Amir Djalovski, Ruth Feldman
Summary: The study highlights the significant impact of maternal contact and caregiving behavior on the development of the social brain in mammalian young, leading to long-term effects on adult sociality. Specifically in human adults, maternal-newborn contact and parenting behavior play a crucial role in shaping the sensitivity of the social brain, particularly in affect-specific empathy.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Behavioral Sciences
Travis C. Evans, Michael Esterman, Jennifer C. Britton
Summary: Social avoidance behavior (SAB) produces impairment in multiple domains and is associated with dysregulated modulation of automatic and subjective approach-avoidance (AA) motivational sensitivity to social reward-threat conflict signals.
COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Melis Yilmaz Balban, Erin Cafaro, Lauren Saue-Fletcher, Marlon J. Washington, Maryam Bijanzadeh, A. Moses Lee, Edward F. Chang, Andrew D. Huberman
Summary: The research found that subjects with high anxiety displayed increased visual scanning behavior in response to threats; the amount of scanning behavior correlated with the magnitude of physiological arousal in both healthy and anxious subjects; eye movements play a key role in how humans detect and adjust to stress in response to visually perceived threats.
Article
Chemistry, Multidisciplinary
Sung Park, Richard Catrambone
Summary: The experiments showed that virtual humans can induce social facilitation through facial appearance and voice, with voice synced facial appearance eliciting stronger social facilitation than voice or face alone. Similar results were found in the politeness norm experiment, where participants who directly evaluated the tutor reported more favorable performance compared to those who evaluated the tutor indirectly.
APPLIED SCIENCES-BASEL
(2021)
Article
Psychiatry
Emil F. Coccaro, Sarah Keedy, Royce Lee, K. Luan Phan
Summary: Social-emotional information processing (SEIP) is crucial for human interaction, involving different phases of processing to understand behavior and respond to social threats. The V-SEIP task activates specific brain regions in different phases, making it a potential neuro-biomarker for studying psychiatric conditions characterized by anger, irritability, and impulsive aggression.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Neurosciences
Yu-Ting Tseng, Binghao Zhao, Shanping Chen, Jialin Ye, Jingjing Liu, Lisha Liang, Hui Ding, Bernhard Schaefke, Qin Yang, Lina Wang, Feng Wang, Liping Wang
Summary: This study found that animals are rapidly aroused from REM sleep when facing threats, in contrast to NREM sleep. Neurons in the medial subthalamic nucleus expressing corticotropin-releasing hormone were identified as being responsible for mediating arousal and defensive responses to predator threats during sleep and wakefulness. These findings suggest that REM sleep responses are adaptive and may have a protective function against threats.
Article
Neurosciences
Smilla Weisser, Madeleine Mueller, Jonas Rauh, Roland Esser, Johannes Fuss, Beat Lutz, Jan Haaker
Summary: This study found that the levels of circulating eCBs increase during the acquisition of threat responses. The elevated eCB levels are associated with physiological and neural responses during threat learning.
NEUROPSYCHOPHARMACOLOGY
(2022)
Review
Virology
Qizan Gong, Changle Wang, Xia Chuai, Sandra Chiu
Summary: This review summarizes the features, transmission pathways, pathogenicity, laboratory diagnosis, and prevention and treatment strategies of human monkeypox. By understanding this information, it provides basic knowledge for the prevention and control of future outbreaks of monkeypox.
Article
Computer Science, Software Engineering
Xing-Da Jhan, Sai-Keung Wong, Elham Ebrahimi, Yuwen Lai, Wei-Chia Huang, Sabarish Babu
Summary: This study empirically investigated the impact of small talk on users' non-verbal behaviors and emotions when interacting with virtual humans with positive behavioral dispositions. The results revealed that virtual humans with small talk capabilities could alter users' emotions and non-verbal behaviors, and there were significant gender differences in non-verbal behaviors in the presence or absence of small talk.
IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS
(2022)
Article
Neurosciences
Aman Taxali, Mike Angstadt, Saige Rutherford, Chandra Sripada
Summary: Recent studies have shown that the use of predictive models can improve the reliability of functional magnetic resonance imaging (fMRI), with the predicted outcomes of these models being more reliable than individual imaging features, reaching good levels of reliability for some methods.
Article
Psychology, Clinical
Sarah J. Brislin, Meghan E. Martz, Sonalee Joshi, Elizabeth R. Duval, Arianna Gard, D. Angus Clark, Luke W. Hyde, Brian M. Hicks, Aman Taxali, Mike Angstadt, Saige Rutherford, Mary M. Heitzeg, Chandra Sripada
Summary: This study found that p, INT, and EXT exhibit well-differentiated nomological networks that are interpretable in terms of neurocognition, impulsivity, fear/distress, and social adversity. These results support their validity as broad psychopathology liabilities.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Psychology, Clinical
D. Angus Clark, Brian M. Hicks, Mike Angstadt, Saige Rutherford, Aman Taxali, Luke Hyde, Alexander S. Weigard, Mary M. Heitzeg, Chandra Sripada
Summary: The study found that although there are theoretical debates about modeling the GFP, the practical implications of these choices for rank-ordering children and assessing external associations will often be modest.
CLINICAL PSYCHOLOGICAL SCIENCE
(2021)
Article
Psychiatry
Ivy F. Tso, Mike Angstadt, Saige Rutherford, Scott Peltier, Vaibhav A. Diwadkar, Stephan F. Taylor
Summary: Abnormal effective connectivity in brain networks associated with eye gaze processing is found in schizophrenia patients, affecting social cognition and functioning. Altered self-connections, inter-regional connections, and explicit gaze discrimination are associated with these abnormalities.
SCHIZOPHRENIA RESEARCH
(2021)
Article
Computer Science, Interdisciplinary Applications
Saige Rutherford, Pascal Sturmfels, Mike Angstadt, Jasmine Hect, Jenna Wiens, Marion van den Heuvel, Dustin Scheinost, Chandra Sripada, Moriah Thomason
Summary: By training a Convolutional Neural Network on manually traced fetal fMRI images, the authors were able to accurately isolate the fetal brain from surrounding tissue across non-stationary 3D brain volumes. They achieved excellent performance on two separate test sets and provided insights into their adaptation of each preprocessing step, representing a significant advancement towards an open-source workflow for fetal functional MRI data preprocessing.
Article
Psychiatry
Chandra Sripada, Mike Angstadt, Aman Taxali, Daniel Kessler, Tristan Greathouse, Saige Rutherford, D. Angus Clark, Luke W. Hyde, Alex Weigard, Sarah J. Brislin, Brian Hicks, Mary Heitzeg
Summary: Convergent research has identified a general factor (P factor) that is associated with altered connectivity patterns across multiple large-scale networks in the human brain, including reduced connectivity within the default network and increased connectivity between the default network and multiple control networks. These findings suggest that the general factor of psychopathology produces attenuating changes across various networks.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Psychiatry
Chandra Sripada, Mike Angstadt, Aman Taxali, D. Angus Clark, Tristan Greathouse, Saige Rutherford, Joseph R. Dickens, Kerby Shedden, Arianna M. Gard, Luke W. Hyde, Alexander Weigard, Mary Heitzeg
Summary: The study found that socioeconomic status and general cognitive ability are related to broad and diffuse differences in functional connectivity architecture during early adolescence, potentially suggesting a mechanism through which socioeconomic status influences cognitive development.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Neurosciences
Nicole E. Neef, Mike Angstadt, Simone P. C. Koenraads, Soo-Eun Chang
Summary: This study found reduced connectivity of the left inferior frontal cortex pars opercularis (IFCop) in children who stutter, particularly in executive, rostral-motor, and caudal-motor corticostriatal projections. In contrast, the right IFCop showed divergent connectivity patterns in stuttering boys. These findings shed light on core deficits in stuttering and challenge existing theories about right hemisphere differences.
Article
Psychiatry
Stefanie Russman Block, Luke J. Norman, Xiaoxi Zhang, Kristin A. Mannella, Huan Yang, Mike Angstadt, James L. Abelson, Joseph A. Himle, Stephan F. Taylor, Kate D. Fitzgerald
Summary: This study found that cortical-subcortical hyperconnectivity related to affective-behavioral integration and cortical network hypoconnectivity related to cognitive control are present in OCD patients. The objective was to examine whether these connectivity patterns predict treatment response. The results showed that ERP produced greater decreases in symptom scores compared to SMT. Decreased connectivity between vmPFC and subcortical regions, especially in unmedicated participants, was associated with ERP.
AMERICAN JOURNAL OF PSYCHIATRY
(2023)
Article
Psychology, Developmental
Chandra Sripada, Arianna M. Gard, Mike Angstadt, Aman Taxali, Tristan Greathouse, Katherine McCurry, Luke W. Hyde, Alexander Weigard, Peter Walczyk, Mary Heitzeg
Summary: This study investigates the impact of limited socioeconomic resources (SER) on brain connectivity patterns in adolescents using whole-brain multivariate methods. The findings demonstrate widespread alterations in the connectome associated with SER, with parental education identified as the primary driver of neural associations. These associations are concentrated in somatosensory and subcortical regions and are partially mediated by home enrichment activities, child's cognitive abilities, and grades.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2022)
Meeting Abstract
Neurosciences
Alexander Weigard, Mike Angstadt, Aman Taxali, Zvi Shapiro, Mary Heitzeg, Chandra Sripada
NEUROPSYCHOPHARMACOLOGY
(2022)
Meeting Abstract
Substance Abuse
M. E. Martz, K. L. McCurry, M. Angstadt, M. M. Heitzeg, R. Lash, K. Litinas, S. J. Peltier, M. Soules, C. Vitro, C. S. Sripada
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Meeting Abstract
Neurosciences
Scott Blain, Stephan Taylor, Saige Rutherford, Carly Lasagna, Beier Yao, Mike Angstadt, Michael Green, Timothy Johnson, Scott Peltier, Vaibhav Diwadkar, Ivy Tso
BIOLOGICAL PSYCHIATRY
(2022)
Meeting Abstract
Neurosciences
Alexander Weigard, Mike Angstadt, Aman Taxali, Saige Rutherford, Mary Heitzeg, Chandra Sripada
BIOLOGICAL PSYCHIATRY
(2021)
Meeting Abstract
Neurosciences
Kate Fitzgerald, Luke Norman, Xiaoxi Zhang, Kristin Manella, Mike Angstadt, James Abelson, Joseph Himle, Stephan Taylor
BIOLOGICAL PSYCHIATRY
(2021)
Article
Neurosciences
Jose Sanchez-Bornot, Roberto C. Sotero, J. A. Scott Kelso, Ozguer Simsek, Damien Coyle
Summary: This study proposes a multi-penalized state-space model for analyzing unobserved dynamics, using a data-driven regularization method. Novel algorithms are developed to solve the model, and a cross-validation method is introduced to evaluate regularization parameters. The effectiveness of this method is validated through simulations and real data analysis, enabling a more accurate exploration of cognitive brain functions.
