Article
Medicine, General & Internal
Sung Ho Jang, Jun Lee, Jae Woon Kim, Kyu Tae Choi
Summary: This study found that MRI results, brainstem involvement, and transcranial magnetic stimulation responses were closely related to motor recovery in patients with anterior choroidal artery infarction.
Article
Neurosciences
Lu Wang, Qi-Xiu Zhu, Ming-Hua Zhong, Rui-Zhi Zhou, Xi-Qin Liu, Nai-Su Tang, Xiao-Chen Feng, Cheng-Fei Gao
Summary: This study aimed to explore the optimal efficiency of repetitive transcranial magnetic stimulation (rTMS) to promote upper limb functional recovery after stroke based on bimodal balance-recovery model. The results showed that low-frequency rTMS was superior to high-frequency rTMS in promoting upper limb motor function recovery for stroke patients with high corticospinal tract (CST) integrity, while only high-frequency rTMS had positive effects on stroke patients with low CST integrity.
JOURNAL OF INTEGRATIVE NEUROSCIENCE
(2022)
Article
Health Care Sciences & Services
Sung Ho Jang, Hye Rin Seo, Dong Hyun Byun
Summary: This study investigated the prognosis of ipsilesional corticospinal tracts in early-stage cerebral infarction using follow-up diffusion tensor tractography. The results demonstrated that approximately 20% of patients showed disruption of the ipsilesional CST at the chronic stage. However, the clinical outcomes in hand and gait functions were generally good. Careful interpretation considering the somatotopy of the ipsilesional CST is needed due to the high false-negative results on DTT at the chronic stage.
Article
Neurosciences
Massimo Bertoli, Angela Tataranni, Susanna Porziani, Patrizio Pasqualetti, Eugenia Gianni, Joy Grifoni, Teresa L'Abbate, Karolina Armonaite, Livio Conti, Andrea Cancelli, Carlo Cottone, Franco Marinozzi, Fabiano Bini, Federico Cecconi, Franca Tecchio
Summary: This study tested the effectiveness of a fatigue relief treatment in multiple sclerosis patients by modulating the cortical motor circuitry. The treatment led to positive effects on fatigue symptoms and altered the symmetry of the brain's hemispheres. This research provides new insights into the mechanisms of neuronal functional patterning.
Article
Pediatrics
Hyo Sung Kim, Su Min Son
Summary: This study investigated the relationship between the corticospinal tract (CST) and limb length discrepancy (LLD) in patients with hemiplegic cerebral palsy (CP). The results suggested that patients with hemiplegic CP, especially in the hand, were likely to have LLD. Evaluation of the CST using diffusion tensor tractography may be helpful in assessing and predicting LLD in hemiplegic CP.
Article
Neurosciences
Myriam Taga, Charalambos C. Charalambous, Sharmila Raju, Jing Lin, Yian Zhang, Elisa Stern, Heidi M. Schambra
Summary: The study examined the innervation patterns and connection strength of the corticoreticulospinal tract (CReST) to upper limb muscles in healthy individuals and stroke patients. Results showed stronger connections to the hand in healthy subjects and to the arm in stroke patients. This suggests a key role of CReST in upper limb motor function and recovery in humans.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Article
Neurosciences
Jeong Pyo Seo, Heun Jae Ryu
Summary: This study investigated the potential changes in the mesocortical and mesolimbic tracts following middle cerebral artery (MCA) infarction. The findings showed significant damage to these pathways, which may contribute to our understanding of the pathophysiology of post-stroke depression.
Article
Clinical Neurology
Daniel Ta, Abdullah H. Ishaque, Adam Elamy, Tanushka Anand, Andrew Wu, Dean T. Eurich, Collin Luk, Yee Hong Yang, Sanjay Kalra
Summary: This study investigates the relationship between degeneration of the corticospinal tract (CST) and survival in patients with amyotrophic lateral sclerosis (ALS). Through MRI scans and clinical evaluations, it is found that the texture feature 'autocorrelation' of the CST is associated with survival in patients. These findings suggest the potential of neuroimaging in improving patient management and facilitating clinical trials.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Yeun Jie Yoo, So Yeon Jun, Eun Jin Park, Youngkook Kim
Summary: This study aimed to determine the measurement accuracy of the structural integrity of the corticospinal tract (CST) using diffusion tensor imaging. The results showed that the structural integrity measurements at the pontomedullary junction or entire CST demonstrated the highest accuracy in the subacute phase of stroke for assessing upper limb function.
Article
Neurosciences
Maurits H. J. Hoonhorst, Rinske H. M. Nijland, Cornelis H. Emmelot, Boudewijn J. Kollen, Gert Kwakkel
Summary: The study revealed that approximately 60% of ischemic stroke patients experienced prolonged CMCT in the non-infarcted hemisphere within 48 hours post-stroke. Moreover, sustained prolonged CMCT was more common in patients with no motor recovery.
Article
Neurosciences
Naotsugu Kaneko, Atsushi Sasaki, Yohei Masugi, Kimitaka Nakazawa
Summary: Associative Stimulation (PAS) combining transcutaneous spinal cord stimulation (tSCS) and transcranial magnetic stimulation (TMS) was used to modulate corticospinal excitability in lower-limb muscles. The study found that PAS could facilitate corticospinal excitability in the lower-leg and hamstring muscles under individual-ISI condition, with a spatial gradient of PAS-induced facilitation among lower-limb muscles.
Article
Neurosciences
C. Barbi, G. Vernillo, M. Emadi Andani, G. Giuriato, F. G. Laginestra, A. Cavicchia, G. Fiorini Aloisi, C. Martignon, A. Pedrinolla, F. Schena, M. Venturelli
Summary: Researchers evaluated the accuracy of neuronavigated TMS (nTMS) and a standardized function-guided procedure for maintaining TMS coil position during neuromuscular evaluations. The study found that the spatial accuracy of TMS coil position did not affect corticospinal excitability and inhibition in knee extensors. Variability in MEP and SP responses was attributed to spontaneous fluctuations in corticospinal excitability and inhibition, unaffected by the stability of the stimulation point.
NEUROSCIENCE LETTERS
(2023)
Article
Neurosciences
Jiamin Li, Cen Chen, Shenyu Zhu, Xiulian Niu, Xidan Yu, Jie Ren, Min Shen
Summary: The combination of wrist-ankle acupuncture and 5-Hz repetitive transcranial magnetic stimulation (rTMS) is effective in improving gross motor function and enhancing the conductivity of the corticospinal tract in children with cerebral palsy, but does not show clear clinical superiority in improving spasticity.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Neurosciences
Megha Saini, Neha Singh, Nand Kumar, M. V. Padma Srivastava, Amit Mehndiratta
Summary: This study aimed to determine the correlation between FMA-based upper extremity impairment and neurophysiological parameters of corticospinal tract integrity. The results showed a significant positive correlation between MEP of the EDC muscle and FMA assessment scores, suggesting that FMA may serve as a prognostic indicator of MEP responsiveness.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Guiyuan Cai, Manfeng Wu, Qian Ding, Tuo Lin, Wanqi Li, Yinghua Jing, Hongying Chen, Huiting Cai, Tifei Yuan, Guangqing Xu, Yue Lan
Summary: The study found that the alpha2 power in the sensorimotor region is inversely correlated with corticospinal excitability. Additionally, the global efficiency of the brain network is correlated with corticospinal excitability, showing a positive correlation with global efficiency in the theta band and a negative correlation with global efficiency in the alpha2 band.
FRONTIERS IN NEUROSCIENCE
(2021)
Review
Anesthesiology
Sang Gyu Kwak, Yoo Jin Choo, Min Cheol Chang
Summary: Oral prednisolone can effectively control symptoms in patients with complex regional pain syndrome (CRPS), with a dosage of 30 mg/day being effective and a treatment duration of 1-3 months, but short-term treatment for 1-2 weeks can also be effective, with minor side effects reported in only 0%-30% of patients.
Article
Neurosciences
Jeoung Kun Kim, Min Cheol Chang, Donghwi Park
Summary: The study developed a deep learning algorithm to predict the long-term motor recovery of stroke patients using clinical parameters and brain magnetic resonance images. The results demonstrated that an integrated algorithm trained with patient clinical data and brain MRI obtained soon after ischemic stroke can accurately predict hand function and ambulatory outcomes.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Min Cheol Chang, Sang Gyu Kwak, Jin-Mo Park, Donghwi Park, Jin-Sung Park
Summary: This study compared the clinical characteristics of patients with respiratory, bulbar and limb onset ALS. It found that patients with respiratory onset ALS had higher age, higher ALSFRS-R and lower BMI. The study of the phrenic nerves helped distinguish between respiratory onset ALS and other types of ALS patients.
ACTA NEUROLOGICA BELGICA
(2023)
Review
Medicine, General & Internal
Yoo Jin Choo, Du Hwan Kim, Min Cheol Chang
Summary: This review provides an overview of basic methods for managing amputation stumps, including rehabilitation processes, desensitization, dressing application, prosthesis fitting, and limb positioning to improve the quality of life for amputees.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Letter
Rheumatology
Mathieu Boudier-Reveret, Ming-Yen Hsiao, Min Cheol Chang
RHEUMATOLOGY AND THERAPY
(2022)
Article
Otorhinolaryngology
Ming-Yen Hsiao, Yoo Jin Choo, I-Chun Liu, Mathieu Boudier-Reveret, Min Cheol Chang
Summary: Dysphagia, a common complication of stroke, can be improved with repetitive transcranial magnetic stimulation (rTMS). This study evaluated the effects of different rTMS parameters on post-stroke dysphagia. The results showed that both high-frequency and low-frequency rTMS could improve swallowing function in stroke patients immediately and at 4 weeks after treatment, but the improvement in Penetration-Aspiration Scale (PAS) scores was not significant.
Review
Nutrition & Dietetics
Min Cheol Chang, Yoo Jin Choo
Summary: A meta-analysis was conducted to investigate the effects of whey protein, leucine, and vitamin D supplementation in sarcopenia. It was found that supplementation with whey protein, leucine, and vitamin D can increase muscle mass, and combining with physical exercise can improve muscle strength and function.
Article
Chemistry, Multidisciplinary
Jeoung Kun Kim, Yoo Jin Choo, In Sik Park, Jin-Woo Choi, Donghwi Park, Min Cheol Chang
Summary: This study developed deep-learning algorithms that can automatically prescribe orthotic insoles to patients with foot pain and assess their accuracy.
APPLIED SCIENCES-BASEL
(2023)
Article
Medicine, General & Internal
Min Cheol Chang, Dae Yeong Kim, Jin-Woo Choi, Ho Yong Choi, Jin-Sung Park, Donghwi Park
Summary: In this study, we identified risk factors for dysphagia in patients with cervical spinal cord injury (C-SCI) by analyzing the correlation between clinical factors and the severity of dysphagia. The anterior surgical approach was found to be the only clinical factor significantly correlated with dysphagia severity in C-SCI patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Min Cheol Chang, You Jin Choo, Sang Gyu Kwak, Kiyeun Nam, Sae Yoon Kim, Hee Jin Lee, Soyoung Kwak
Summary: Extracorporeal shockwave therapy (ESWT) has shown effectiveness in reducing spasticity in patients with cerebral palsy (CP), although its duration of effect is limited. A meta-analysis of three studies found that ESWT significantly reduced spasticity, as measured by the modified Ashworth scale, compared to a control group, but the effect only lasted for 1 month. However, significant improvements in passive ankle range of motion and plantar surface area were observed for up to 3 months. ESWT appears to be a useful and effective therapeutic option for managing spasticity in patients with CP.
Review
Health Care Sciences & Services
Dong Ah Shin, Yoo Jin Choo, Min Cheol Chang
Summary: Spinal injection is an effective treatment for spinal pain and is widely used in the clinical field. It helps locate the source of pain, reduces pain, improves quality of life, and can potentially avoid the need for spinal surgery.
Review
Health Care Sciences & Services
Min Cheol Chang, Jeoung Kun Kim, Donghwi Park, Jang Hwan Kim, Chung Reen Kim, Yoo Jin Choo
Summary: Applications of machine learning in the healthcare field have become increasingly diverse. This review investigated the integration of artificial intelligence (AI) in predicting the prognosis of patients with central nervous system disorders. While AI algorithms have shown promise in prognostic assessment, challenges remain in achieving higher prediction accuracy for practical clinical use. Accruing diverse data, including medical imaging and collaborative efforts among hospitals, can enhance the predictive capabilities of AI. As healthcare professionals become more familiar with AI, its role in central nervous system rehabilitation is expected to advance significantly, revolutionizing patient care.
Review
Health Care Sciences & Services
Seoyon Yang, Mathieu Boudier-Reveret, You Gyoung Yi, Kee Yong Hong, Min Cheol Chang
Summary: The study investigated the effectiveness of treatment programs in managing neck pain in patients with forward head posture (FHP). The results showed that various treatment programs, including postural corrective exercises and manual therapy, were beneficial for improving pain and disability in patients with FHP.
Article
Anesthesiology
Sang Hoon Lee, Hyun Hee Choi, Min Cheol Chang
Summary: This study evaluated the efficacy of ultrasound-guided partial release of the transverse carpal ligament using an 18-G needle in patients with refractory carpal tunnel syndrome. The results showed that 86.2% of patients achieved successful treatment outcomes at 6 months post-treatment, with significant reduction in average NRS scores.
Letter
Clinical Neurology
Min Cheol Chang
KOREAN JOURNAL OF PAIN
(2022)
