Article
Clinical Neurology
Qian Xiao, Zhou Wu, Xiuqing Hui, Qing Jiao, Yuan Zhong, Linyan Su, Guangming Lu
Summary: This study found differences in neural activities during emotional response inhibition between manic and euthymic pediatric bipolar disorder patients. Manic patients showed increased activities in certain brain regions compared to euthymic patients, and this hyperactivity was positively associated with false response errors. Increased activity in the left superior frontal gyrus may be characteristic of manic episodes in pediatric bipolar disorder patients, contributing to more severe emotional dysregulation.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Neurosciences
Yi-Bing Guo, Qing Jiao, Xiao-Tong Zhang, Qian Xiao, Zhou Wu, Wei-Fang Cao, Dong Cui, Guang-Hui Yu, Ru-Hai Dou, Lin-Yan Su, Guang-Ming Lu
Summary: This study investigated the fractal characteristics of brain blood oxygen level-dependent signals in pediatric bipolar disorder patients when responding to external emotional stimuli. The findings showed that patients exhibited overactivation, increased self-similarity, and decreased complexity during an emotional task compared to healthy controls. These results provide evidence of altered emotional modulation of cognitive control in pediatric bipolar disorder patients.
Article
Psychology, Biological
Sebastian Ludyga, Wenke Mohring, Henning Budde, Nick Hirt, Uwe Puhse, Markus Gerber
Summary: The study found a moderate association between motor skills and behavioral performance on a Go/NoGo task, fully mediated by the P300 component in the NoGo condition. In contrast, cardiorespiratory fitness was associated with N200, while motor skills were associated with P300 in children.
Review
Oncology
Ryan C. Perez, DaeHee Kim, Aaron W. P. Maxwell, Juan C. Camacho
Summary: The association between hypoxia, cancer aggressiveness, and decreased therapeutic response is well-established. This review aims to summarize the molecular pathways associated with tumor hypoxia and the use of PET and MRI techniques for imaging hypoxia in cancer. It also discusses future directions and challenges in this field.
Article
Neurosciences
Lisanne F. Ten Brinke, Chun Liang Hsu, Kirk Erickson, Todd C. Handy, Teresa Liu-Ambrose
Summary: Evidence suggests that CCT may improve executive functions by decreasing the correlation between the default mode network (DMN) and fronto-parietal network (FPN). Compared to BAT, independent CCT also significantly reduced the correlation between certain brain regions.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Neurosciences
Long-Biao Cui, Yu-Fei Fu, Lin Liu, Xu-Sha Wu, Yi-Bin Xi, Hua-Ning Wang, Wei Qin, Hong Yin
Summary: This study utilized multimodal neuroimaging features to predict treatment responses in schizophrenia patients, combining structural and functional MRI data. The results demonstrated that combining structural and functional features resulted in more accurate prediction of treatment response, providing important insights for more effective therapeutic strategies.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Zi-Jian Cheng, Lingxiao Yang, Wen-Hao Zhang, Ru-Yuan Zhang
Summary: The effects of response correlations among neurons and voxel populations have been a subject of debate in computational neuroscience. In this study, we used functional magnetic resonance imaging (fMRI) to investigate the effects of response correlations in the human visual cortex. We found that voxelwise response correlations generally enhance stimulus information, contrary to previous empirical neurophysiological studies. Our results suggest that multivariate fMRI data contain rich statistical structures that are directly related to sensory information representation.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Chemistry, Analytical
Alessandro Carollo, Paola Rigo, Andrea Bizzego, Albert Lee, Peipei Setoh, Gianluca Esposito
Summary: Recent migration and globalization trends have resulted in ethnically, religiously, and linguistically diverse countries. This study aimed to investigate the neural signature of in-group bias in a multicultural context and explore the relationship between brain activity and system-justifying ideologies. The results showed enhanced brain activity in regions associated with mentalization, empathetic resonance, and social cognition when participants were exposed to in-group (Chinese) faces compared to out-group faces.
Article
Biochemical Research Methods
Marius E. Mayerhoefer, Lale Umutlu, Heiko Schoeder
Summary: Lymphomas are ideal targets for radiomics due to their distinct characteristics, and functional imaging tests play a crucial role in diagnosing and predicting treatment outcomes for lymphoma. However, more data is needed to support the application of radiomics in lymphoma due to differences in lymphoma subtypes and increasing treatment options.
Article
Radiology, Nuclear Medicine & Medical Imaging
Niels W. Schurink, Simon R. van Kranen, Joost J. M. van Griethuysen, Sander Roberti, Petur Snaebjornsson, Frans C. H. Bakers, Shira H. de Bie, Gerlof P. T. Bosma, Vincent C. Cappendijk, Remy W. F. Geenen, Peter A. Neijenhuis, Gerald M. Peterson, Cornelis J. Veeken, Roy F. A. Vliegen, Femke P. Peters, Nino Bogveradze, Najim el Khababi, Max J. Lahaye, Monique Maas, Geerard L. Beets, Regina G. H. Beets-Tan, Doenja M. J. Lambregts
Summary: This study aims to develop and validate a multiparametric model to predict neoadjuvant treatment response in rectal cancer using a heterogeneous multicenter MRI dataset.
EUROPEAN RADIOLOGY
(2023)
Article
Engineering, Multidisciplinary
Amir Mohammad Ghani Dehkordi, Alireza Kashaninia, Fardad Farokhi, Nader Jafarnia Dabanloo
Summary: This study presents a five-step algorithm to determine functional brain connections in Alzheimer's disease using Molecular Dynamics method in functional MRI images. The results indicate a significant decrease in memory connections over time in Alzheimer's patients.
ENGINEERING ANALYSIS WITH BOUNDARY ELEMENTS
(2023)
Article
Anesthesiology
Xiang Ye, Pai-Feng Yang, Qing Liu, Barbara D. Dillenburger, Robert M. Friedman, Li Min Chen
Summary: This study used fMRI-guided microelectrode mapping and recording studies in squirrel monkeys to reveal a clustering of heat nociceptive neurons in the parietal operculum region, shedding light on the unique functional organization of thermal nociception in the primate brain. The findings suggest the existence of a modality-preferred heat nociceptive patch that is spatially separated and intermingled with other sensory patches in the primate opercular cortex.
Article
Neurosciences
Hui Wang, Jianxia Xu, Miao Yu, Gaiyan Zhou, Jingru Ren, Yajie Wang, Huifen Zheng, Yu Sun, Jun Wu, Weiguo Liu
Summary: This study aimed to explore the potential clinical utility of functional and structural magnetic resonance imaging (MRI) in the diagnosis of depression in Parkinson's disease (DPD). The results showed that both the ReHo value of the left dorsolateral superior frontal gyrus and the DC value of the left inferior temporal gyrus were equally well suited for the diagnosis and differential diagnosis of DPD, with a combination of them being slightly preferable. The multimodal MRI technique represents a promising approach for the classification of subjects with PD.
FRONTIERS IN NEUROSCIENCE
(2023)
Editorial Material
Oncology
Quinlan Cullen, Kayvan R. Keshari
Summary: Although immune checkpoint blockade therapy has shown remarkable clinical success, its efficacy is limited to a minority of patients and predicting treatment response remains challenging. Saida and colleagues utilized advanced molecular imaging modalities to study changes in the tumor microenvironment that correlate with response to immune checkpoint blockade therapy, offering potential imaging biomarkers for assessing clinical response to immunotherapy.
Article
Radiology, Nuclear Medicine & Medical Imaging
Yuvnik Trada, Paul Keall, Michael Jameson, Daniel Moses, Peter Lin, Phillip Chlap, Lois Holloway, Myo Min, Dion Forstner, Allan Fowler, Mark T. Lee
Summary: Combining DWI MRI and FDG-PET/CT for measuring tumor changes during radiotherapy can predict treatment response in mucosal head and neck carcinoma. Evaluating ADC mean and MTV together improves the accuracy of predicting local recurrence.
EUROPEAN RADIOLOGY
(2023)
Article
Psychiatry
Sjoerd J. H. Ebisch, Vittorio Gallese, Anatolia Salone, Giovanni Martinotti, Giuseppe di Iorio, Dante Mantini, Mauro Gianni Perrucci, Gian Luca Romani, Massimo Di Giannantonio, Georg Northoff
SCHIZOPHRENIA RESEARCH
(2018)
Article
Neurosciences
Filippo Zappasodi, Mauro Gianni Perrucci, Aristide Saggino, Pierpaolo Croce, Pasqua Mercuri, Roberta Romanelli, Roberto Colom, Sjoerd J. H. Ebisch
Article
Neurosciences
Roberto Guidotti, Annalisa Tosoni, Mauro Gianni Perrucci, Carlo Sestieri
Article
Neurosciences
Giovanna Bubbico, Piero Chiacchiaretta, Matteo Parenti, Marcin di Marco, Valentina Panaraf, Gianna Sepedet, Antonio Ferretti, Mauro Gianni Perrucci
FRONTIERS IN NEUROSCIENCE
(2019)
Article
Multidisciplinary Sciences
Hiroki Nakata, Ryo Domoto, Nobuaki Mizuguchi, Kiwako Sakamoto, Kazuyuki Kanosue
Article
Multidisciplinary Sciences
Sara Di Marco, Annalisa Tosoni, Emanuele Cosimo Altomare, Gabriele Ferretti, Mauro Gianni Perrucci, Giorgia Committeri
SCIENTIFIC REPORTS
(2019)
Article
Multidisciplinary Sciences
Francesco Cerritelli, Piero Chiacchiaretta, Francesco Gambi, Raoul Saggini, Mauro Gianni Perrucci, Antonio Ferretti
Summary: In this study, the combination of rCBF and HRV measures showed that OMT treatment can significantly regulate brain-heart interaction mechanisms, leading to decreased rCBF in pain matrix regions and increased rCBF in other brain areas. These findings suggest that OMT may play a role in modulating brain-heart interactions.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Mario Paci, Giulio Di Cosmo, Mauro Gianni Perrucci, Francesca Ferri, Marcello Costantini
Summary: Inhibitory control is the ability to suppress inappropriate movements and unwanted actions. Individual differences in intracortical inhibition within M1 may contribute to behavioral differences in actual inhibitory capacities, as reflected by the correlation between GABA(B)ergic-mediated inhibition and action stopping abilities.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Roberto Guidotti, Cosimo Del Gratta, Mauro Gianni Perrucci, Gian Luca Romani, Antonino Raffone
Summary: Neuroscientific studies have explored the effects of intensive mental training based on meditation on the organization of the human brain, but the impact of long-term practice of main forms of meditation on connectivity patterns in large-scale brain networks remains to be fully understood. Functional Magnetic Resonance Imaging (fMRI) and multivariate pattern analysis have been used to investigate the impact of meditation expertise and age on functional connectivity patterns, revealing that expertise-predictive patterns are differently affected by Focused Attention (FA) and Open Monitoring (OM), while age-predictive patterns are not influenced by the meditation form. The study suggests that meditation expertise is associated with specific neuroplastic changes in connectivity patterns within and between multiple brain networks.
Article
Multidisciplinary Sciences
Sara Spadone, Mauro Gianni Perrucci, Giulio Di Cosmo, Marcello Costantini, Stefania Della Penna, Francesca Ferri
Summary: The study investigates the role of functional connectivity in sensorimotor representations, revealing stronger connectivity between the premotor cortex and frontal and parietal regions when processing near space, as well as greater variability in connectivity during the processing of far space.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Sjoerd J. H. Ebisch, Andrea Scalabrini, Georg Northoff, Clara Mucci, Maria Rita Sergi, Aristide Saggino, Antonio Aquino, Francesca R. Alparone, Mauro Gianni Perrucci, Vittorio Gallese, Simone Di Plinio
Summary: Empathy, an important personality trait related to social inclination, is supported by multilevel neuronal network functioning. This study found that intrinsic brain network architecture is related to different dimensions of empathy, with fronto-parietal network associated with vicarious experience and sensorimotor and subcortical networks associated with intuitive understanding. These findings contribute to our understanding of the impact of the brain on empathy and may have implications for studying the effects of brain damage or stimulation on empathy-related network integrity.
Review
Neurosciences
Antonino Raffone, Laura Marzetti, Cosimo Del Gratta, Mauro Gianni Perrucci, Gian Luca Romani, Vittorio Pizzella
Article
Psychology, Experimental
Simone Di Plinio, Simone Arno, Mauro Gianni Perrucci, Sjoerd J. H. Ebisch
CONSCIOUSNESS AND COGNITION
(2019)
Proceedings Paper
Engineering, Biomedical
R. Guidotti, C. Del Gratta, M. G. Perrucci, G. L. Romani, A. Raffone
Article
Psychology, Multidisciplinary
Eiji Watanabe, Akiyoshi Kitaoka, Kiwako Sakamoto, Masaki Yasugi, Kenta Tanaka
FRONTIERS IN PSYCHOLOGY
(2018)
Article
Neurosciences
Jose Sanchez-Bornot, Roberto C. Sotero, J. A. Scott Kelso, Ozguer Simsek, Damien Coyle
Summary: This study proposes a multi-penalized state-space model for analyzing unobserved dynamics, using a data-driven regularization method. Novel algorithms are developed to solve the model, and a cross-validation method is introduced to evaluate regularization parameters. The effectiveness of this method is validated through simulations and real data analysis, enabling a more accurate exploration of cognitive brain functions.
