Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue

Angiogenic growth factor axis in autophagy regulation

(2013) Marissa J. Stanton et al.   Autophagy

Stress granules in neurodegeneration - lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma

(2013) Eva Bentmann et al.   FEBS Journal

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

(2013) Caroline Vance et al.   HUMAN MOLECULAR GENETICS

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Evolution of the human gastrokine locus and confounding factors regarding the pseudogenicity of GKN3

(2013) Jessica H. Geahlen et al.   PHYSIOLOGICAL GENOMICS

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

(2013) Diane Moujalled et al.   PLoS One

T-cell Intracellular Antigen (TIA)-Proteins Deficiency in Murine Embryonic Fibroblasts Alters Cell Cycle Progression and Induces Autophagy

(2013) Carmen Sánchez-Jiménez et al.   PLoS One

TDP-43, an ALS Linked Protein, Regulates Fat Deposition and Glucose Homeostasis

(2013) Nancy R. Stallings et al.   PLoS One

ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43

(2013) E. S. Arnold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

(2012) Diana Jurk et al.   AGING CELL

Antibodies to contactin-1 in chronic inflammatory demyelinating polyneuropathy

(2012) Luis Querol et al.   ANNALS OF NEUROLOGY

Misregulated RNA processing in amyotrophic lateral sclerosis

(2012) Magdalini Polymenidou et al.   BRAIN RESEARCH

TDP-43 aggregation in neurodegeneration: Are stress granules the key?

(2012) Colleen M. Dewey et al.   BRAIN RESEARCH

Neuropathy target esterase (NTE): overview and future

(2012) Rudy J. Richardson et al.   CHEMICO-BIOLOGICAL INTERACTIONS

RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations

(2012) J. G. Daigle et al.   HUMAN MOLECULAR GENETICS

Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis

(2012) Manal A. Farg et al.   HUMAN MOLECULAR GENETICS

Contrasting Pathology of the Stress Granule Proteins TIA-1 and G3BP in Tauopathies

(2012) T. Vanderweyde et al.   JOURNAL OF NEUROSCIENCE

The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity

(2012) David A. Buchner et al.   MAMMALIAN GENOME

Regulated protein aggregation: stress granules and neurodegeneration

(2012) Benjamin Wolozin   Molecular Neurodegeneration

ATXN2 and Its Neighbouring Gene SH2B3 Are Associated with Increased ALS Risk in the Turkish Population

(2012) Suna Lahut et al.   PLoS One

The Cell Neural Adhesion Molecule Contactin-2 (TAG-1) Is Beneficial for Functional Recovery after Spinal Cord Injury in Adult Zebrafish

(2012) Jin-Fei Lin et al.   PLoS One

Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients

(2011) T. Lee et al.   HUMAN MOLECULAR GENETICS

TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1

(2011) Karli K. McDonald et al.   HUMAN MOLECULAR GENETICS

Fatty Acids and Hypoxia Stimulate the Expression and Secretion of the Adipokine ANGPTL4 (Angiopoietin-Like Protein 4/ Fasting-Induced Adipose Factor) by Human Adipocytes

(2011) Pedro González-Muniesa et al.   Journal of Nutrigenetics and Nutrigenomics

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

(2011) Laura Ferraiuolo et al.   Nature Reviews Neurology

The modulation of Amyotrophic Lateral Sclerosis risk by Ataxin-2 intermediate polyglutamine expansions is a specific effect

(2011) Suzana Gispert et al.   NEUROBIOLOGY OF DISEASE

Serum-Nutrient Starvation Induces Cell Death Mediated by Bax and Puma That Is Counteracted by p21 and Unmasked by Bcl-xL Inhibition

(2011) Frédérique Braun et al.   PLoS One

A Focal Epilepsy and Intellectual Disability Syndrome Is Due to a Mutation in TBC1D24

(2010) Mark A. Corbett et al.   AMERICAN JOURNAL OF HUMAN GENETICS

TBC1D24, an ARF6-Interacting Protein, Is Mutated in Familial Infantile Myoclonic Epilepsy

(2010) Antonio Falace et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

(2010) Daryl A. Bosco et al.   HUMAN MOLECULAR GENETICS

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

(2010) Andrew C. Elden et al.   NATURE

Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue

(2010) Liqun Liu-Yesucevitz et al.   PLoS One

Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism

(2010) P.-M. Chiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAs

(2009) Vidya Balagopal et al.   CURRENT OPINION IN CELL BIOLOGY

Diacylglycerol Enrichment of Endoplasmic Reticulum or Lipid Droplets Recruits Perilipin 3/TIP47 during Lipid Storage and Mobilization

(2009) James R. Skinner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism

(2009) Suneil K. Koliwad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane insertion of the FYVE domain is modulated by pH

(2009) Ju He et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A role for lipid droplets in inter-membrane lipid traffic

(2009) John K. Zehmer et al.   PROTEOMICS

Depletion of T-cell intracellular antigen proteins promotes cell proliferation

(2009) Raquel Reyes et al.   GENOME BIOLOGY

Mfsd2aencodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis

(2008) Martin Angers et al.   BIOCHEMICAL JOURNAL

Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system

(2008) M. Osterfield et al.   DEVELOPMENT

The cell adhesion molecule Tag1, transmembrane protein Stbm/Vangl2, and Lamininα1 exhibit genetic interactions during migration of facial branchiomotor neurons in zebrafish

(2008) Vinoth Sittaramane et al.   DEVELOPMENTAL BIOLOGY

Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice

(2008) Isabel Lastres-Becker et al.   HUMAN MOLECULAR GENETICS

R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population

(2008) D. Meyre et al.   HUMAN MOLECULAR GENETICS

Pulse Inhibition of Histone Deacetylases Induces Complete Resistance to Oxidative Death in Cortical Neurons without Toxicity and Reveals a Role for Cytoplasmic p21waf1/cip1 in Cell Cycle-Independent Neuroprotection

(2008) B. Langley et al.   JOURNAL OF NEUROSCIENCE

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

(2008) Takbum Ohn et al.   NATURE CELL BIOLOGY

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

(2008) Alexandra Chadt et al.   NATURE GENETICS

BIG-2 Mediates Olfactory Axon Convergence to Target Glomeruli

(2008) Tomomi Kaneko-Goto et al.   NEURON