Article
Cardiac & Cardiovascular Systems
Jairo Rodriguez Padilla, Robert D. Anderson, Christian Joens, Stephane Masse, Abhishek Bhaskaran, Ahmed Niri, Patrick Lai, Mohammed Ali Azam, Geoffrey Lee, Edward Vigmond, Kumaraswamy Nanthakumar
Summary: This study compared the accuracy of two-dimensional (2D) and three-dimensional (3D) conduction velocity (CV) algorithms in heart models, and examined the influence of mapping resolution on the results. The findings showed that 2D CV was significantly higher than 3D CV, and increased as the resolution decreased.
Article
Computer Science, Interdisciplinary Applications
Annejet Heida, Willemijn F. B. van der Does, Mathijs S. van Schie, Lianne N. van Staveren, Yannick J. H. J. Taverne, Ad J. J. C. Bogers, Natasja M. S. de Groot
Summary: This study compared conduction heterogeneity between the supervulnerable period after electrical cardioversion and long-term sinus rhythm in patients with atrial fibrillation (AF). The findings suggest that there might be no difference in biatrial conduction characteristics between these two periods.
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2023)
Article
Multidisciplinary Sciences
Christopher O'Shea, James Winter, S. Nashitha Kabir, Molly O'Reilly, Simon P. Wells, Olivia Baines, Laura C. Sommerfeld, Joao Correia, Ming Lei, Paulus Kirchhof, Andrew P. Holmes, Larissa Fabritz, Kashif Rajpoot, Davor Pavlovic
Summary: Optical mapping is a widely used technique in pre-clinical cardiac research, allowing for efficient study of cardiac electrophysiology and the effects of interventions on arrhythmia.
Article
Cardiac & Cardiovascular Systems
Kenji Hashimoto, Takehiro Kimura, Yuta Seki, Susumu Ibe, Terumasa Yamashita, Hiroshi Miyama, Taishi Fujisawa, Yoshinori Katsumata, Keiichi Fukuda, Seiji Takatsuki
Summary: This study aimed to clarify the characteristics of conduction gaps during atrial fibrillation ablation by analyzing bidirectional activation maps. The study found that the entrances and exits of electrical conduction gaps were separated, especially in the roof region, indicating that epicardial conduction might contribute to gap formation. These findings provide clues for addressing the problem of conduction gaps during surgery.
Article
Medicine, General & Internal
Theresa Isabelle Wilhelm, Thorsten Lewalter, Johannes Fischer, Judith Reiser, Julia Werner, Christine Baumgartner, Lukas Gleirscher, Petra Hoppmann, Christian Kupatt, Klaus Tiemann, Clemens Jilek
Summary: In this study, ultra-high-density mapping was used to analyze the electrical anatomy of healthy pig hearts. The left chambers showed higher velocity values and voltage amplitudes compared to the right chambers. There was a slightly positive correlation between slow conduction velocities and low voltage amplitudes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
F. Daniel Ramirez, Marianna Meo, Corentin Dallet, Philipp Krisai, Konstantinos Vlachos, Antonio Frontera, Masateru Takigawa, Yosuke Nakatani, Takashi Nakashima, Clementine Andre, Tsukasa Kamakura, Takamitsu Takagi, Aline Carapezzi, Romain Tixier, Remi Chauvel, Ghassen Cheniti, Josselin Duchateau, Thomas Pambrun, Frederic Sacher, Mfileze Hocini, Michel Haissaguerre, Pierre Jais, Remi Dubois, Nicolas Derval
Summary: This study aimed to evaluate the diagnostic performance of bipolar voltage thresholds in identifying regions of slow conduction during reentrant atrial tachycardias. The results showed that bipolar voltage can predict regions of slow conduction, but the correlation between voltage and conduction velocity is modest. Furthermore, no clinical predictors of AT circuit dimensions were identified.
Article
Physiology
Jimena G. Siles-Paredes, Christopher J. Crowley, Flavio H. Fenton, Neal Bhatia, Shahriar Iravanian, Italo Sandoval, Stefan Pollnow, Olaf Dossel, Joao Salinet, Ilija Uzelac
Summary: This study proposes a method for local CV calculation from optical mapping measurements, which can characterize electrical conductivity and infer the depth of ablation lesions, providing new insights for guided ablation therapies.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Lingyu Xu, Sohail Zahid, Mirmilad Khoshknab, Juwann Moss, Ronald D. Berger, Jonathan Chrispin, David Callans, Francis E. Marchlinski, Stefan L. Zimmerman, Yuchi Han, Benoit Desjardins, Natalia Trayanova, Saman Nazarian
Summary: Myocardial lipomatous metaplasia (LM) is associated with post-infarct ventricular tachycardia (VT) circuitry, possibly mediated by slowing nearby corridor conduction velocity (CV) to facilitate circuit re-entry.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Joshua Hawson, Robert D. Anderson, Ahmed Al-kaisey, David Chieng, Louise Segan, Troy Watts, Timothy Campbell, Joseph Morton, Alexander McLellan, Peter Kistler, Aleksander Voskoboinik, Bhupesh Pathik, Saurabh Kumar, Jonathan Kalman, Geoffrey Lee
Summary: This study describes the utility of automated conduction velocity mapping (ACVM) in ventricular tachycardia (VT) ablation. ACVM can accurately resolve complex VT circuits and identify slow conduction zones, but its accuracy is limited in substrate-based mapping.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Enrico Chieffo, Sabato D'Amore, Valentina De Regibus, Cinzia Dossena, Laura Frigerio, Erika Taravelli, Carolina Ferrazzano, Pasquale De Iuliis, Michele Cacucci, Maurizio E. Landolina
Summary: This study evaluated a new tool for identifying slow pathway (SP) using automatic activation mapping, demonstrating it to be an innovative, safe, and effective approach for AVNRT ablation. The latest CARTO3 (R) V7 system was able to accurately map the SP region, leading to successful RF catheter ablation with no adverse events and no recurrences of AVNRT during follow-up.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cell Biology
Bo Han, Mark L. Trew, Callum M. Zgierski-Johnston
Summary: Cardiac electrophysiological disorders, especially arrhythmias, are a major cause of morbidity and mortality worldwide. Altered conduction velocity (CV) is a key substrate for arrhythmogenesis, and understanding methods and determinants of CV is crucial for preventing arrhythmias.
Article
Geochemistry & Geophysics
Kimihiro Mochizuki, Stuart Henrys, Daisuke Haijima, Emily Warren-Smith, Bill Fry
Summary: Through the deployment of Ocean Bottom Seismographs along the northern Hikurangi subduction zone in New Zealand, researchers located 2005 earthquakes and obtained detailed 3-D models for Vp and Vs. They found high Vp/Vs and low Vp/Vs regions, with seismicity concentrated in areas with high Vp/Vs. The variations in Vp/Vs structure along the subducting Hikurangi Plateau may be influenced by dehydration processes caused by reactivated bending-related faults.
EARTH AND PLANETARY SCIENCE LETTERS
(2021)
Article
Cardiac & Cardiovascular Systems
Deborah Nairn, Martin Eichenlaub, Bjoern Mueller-Edenborn, Taiyuan Huang, Heiko Lehrmann, Claudia Nagel, Luca Azzolin, Giorgio Luongo, Rosa M. Figueras Ventura, Barbara Rubio Forcada, AnnaValles Colomer, Dirk Westermann, Thomas Arentz, Olaf Doessel, Axel Loewe, Amir Jadidi
Summary: This study compares different detection methods for atrial cardiomyopathy and finds that the new image intensity threshold method improves diagnostic consistency. These methods may help predict rhythm outcomes after treatment for persistent atrial fibrillation.
Article
Cardiac & Cardiovascular Systems
Hassan Khan, Matthew R. Bonvissuto, Elizabeth Rosinski, Mohamed Shokr, Kara Metcalf, Lior Jankelson, Alexander Kushnir, David S. Park, Scott A. Bernstein, Michael A. Spinelli, Anthony Aizer, Douglas Holmes, Larry A. Chinitz, Chirag R. Barbhaiya
Summary: This study evaluated the relative utility of different substrate mapping techniques for VT ablation. ILAM, fractionation, and CV mapping each identified distinct critical sites and provided a smaller area of interest than did voltage mapping alone. The sensitivity of novel mapping modalities improved with greater local point density.
Article
Physics, Multidisciplinary
Niels F. Otani, Eileen Figueroa, James Garrison, Michelle Hewson, Laura Munoz, Flavio H. Fenton, Alain Karma, Seth H. Weinberg
Summary: Previous computer simulations have shown that existing models of action potential wave propagation in the heart do not match observed wave propagation behavior. However, we have found that this discrepancy can be resolved by introducing ephaptic coupling as a primary factor in wave front propagation. This not only provides support for the importance of ephaptic coupling in normal wave propagation, but also helps to explain the discordant alternans patterns observed in experiments.
PHYSICAL REVIEW LETTERS
(2023)