Article
Gastroenterology & Hepatology
Hisashi Fukuda, Hiroki Sato, Yusuke Fujiyoshi, Hirofumi Abe, Hiroki Okada, Junya Shiota, Chiaki Sato, Hiroyuki Sakae, Masaki Ominami, Yoshitaka Hata, Ryo Ogawa, Jun Nakamura, Tetsuya Tatsuta, Yuichiro Ikebuchi, Hiroshi Yokomichi, Hironori Yamamoto, Haruhiro Inoue
Summary: This study aimed to investigate the etiology of chest pain in achalasia-related esophageal motility disorders and the frequency of persistent chest pain after POEM. The results showed that age, sex, disease duration, and prior treatment were related to the prevalence and severity of chest pain. POEM had satisfactory efficacy, but residual pain was often observed.
GASTROINTESTINAL ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Apichet Sirinawasatien, Pallop Sakulthongthawin
Summary: Jackhammer esophagus is a rare esophageal motility disorder that can cause symptoms like dysphagia. High-resolution manometry and upper gastrointestinal endoscopy are key in diagnosis, with treatment options including calcium channel blockers and proton pump inhibitors.
BMC GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Koichi Muroi, Naomi Kakushima, Kazuhiro Furukawa, Eri Ishikawa, Tsunaki Sawada, Takuya Ishikawa, Keiko Maeda, Takeshi Yamamura, Eizaburo Ohno, Masanao Nakamura, Hiroki Kawashima, Kohei Funasaka, Ryoji Miyahara, Mitsuhiro Fujishiro
Summary: In this study, EoE patients with subjective symptoms were found to have thicker esophageal walls and higher esophageal body pressure. Treatment may reduce esophageal thickness and pressure, leading to improvement of subjective symptoms.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Gastroenterology & Hepatology
Yan Wang, Yu Ding, Lin Lin, Liu Qin Jiang
Summary: This study aimed to assess the role of EGJ-CI in patients with refractory GERD symptoms and found that EGJ-CI is inversely correlated with acid exposure time and reflux episodes, while positively correlated with MNBI, distal contractile integral, lower esophageal sphincter basal pressure, and integrated relaxation pressure. In addition, patients with a low EGJ-CI had a significantly lower MNBI level compared to those with a high EGJ-CI.
JOURNAL OF DIGESTIVE DISEASES
(2021)
Article
Gastroenterology & Hepatology
Brent Hiramoto, Walker D. Redd, Mayssan Muftah, Saikiran Jonnadula, Noreen C. Okwara, Andrew Jenkins, Eliza Cricco-Lizza, Darren J. H. Lee, Jennifer X. Cai, Walter W. Chan
Summary: Obesity is associated with increased esophageal symptom burden and worse physical health-related quality of life, which correlate with higher acid/bolus reflux burden but not altered esophageal motility/transit/contractile reserve. Among patients with esophageal symptoms, higher obesity classes were associated with increased symptom burden, worse health-related quality of life, and more significant reflux burden, but not esophageal motility, transit, and contractile reserve.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Review
Medicine, General & Internal
Gina Gamal Naguib, Mohamed Hassan, Ahmed I. Elshafie, M. G. Naguib
Summary: This study is the first descriptive study to determine the prevalence of esophageal motility abnormalities in Egyptian patients complaining of upper GI symptoms. The results showed that high-resolution manometry is very important for patients with upper GI symptoms.
EGYPTIAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Engineering, Multidisciplinary
Chaoyong Ma, Xingjie Ma, Yonggang Xu, Ling Xiang, Kun Zhang
Summary: A time-frequency domain signal decomposition method based on enhanced seeded region growing (ESRG) is proposed in this paper to identify and extract components in the signal with high accuracy and self-adaptability. The method has the capability to reduce noise interference and can be successfully applied to fault diagnosis.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2022)
Article
Gastroenterology & Hepatology
Wei-Yi Lei, C. Prakash Gyawali, Wei-Chuan Chang, Sabine Roman, Ming Wun Wong, Chih-Hsun Yi, Tso-Tsai Liu, Jui-Sheng Hung, Shu-Wei Liang, Chien-Lin Chen
Summary: The study showed that performing water swallows during straight leg raise can improve esophageal peristaltic performance and predict esophageal contraction reserve.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Review
Gastroenterology & Hepatology
Kelli DeLay, Rena Yadlapati, John E. Pandolfino
Summary: The Chicago Classification (CC) is a dynamic and evolving classification scheme created by a diverse group of international esophageal experts. Its application has transformed the way esophageal motor data are used to define motility disorders, seeking to advance, simplify, and standardize diagnostic methods globally. The most recent update, CC version 4.0 (CCv4.0), emphasizes the importance of clinical context and distinguishes clinically relevant manometric diagnoses from irrelevant observations.
INDIAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Celia Gouynou, Francois Philit, Francois Mion, Francois Tronc, Agathe Senechal, Joris Giai, Anne-Marie Rabain, Jean-Francois Mornex, Sabine Roman
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY
(2020)
Article
Gastroenterology & Hepatology
Sara Philonenko, Sabine Roman, Frank Zerbib, Guillaume Gourcerol, Nathalie Gault, Alain Ropert, Stanislas Bruley des Varannes, Maximilien Barret, Veronique Vitton, Michel Bouchoucha, Nicolas Billar, Caroline Gorbatchef, Henri Duboc, Benoit Coffin
NEUROGASTROENTEROLOGY AND MOTILITY
(2020)
Article
Gastroenterology & Hepatology
Wei-Yi Lei, C. Prakash Gyawali, Wei-Chuan Chang, Sabine Roman, Ming Wun Wong, Chih-Hsun Yi, Tso-Tsai Liu, Jui-Sheng Hung, Shu-Wei Liang, Chien-Lin Chen
Summary: The study showed that performing water swallows during straight leg raise can improve esophageal peristaltic performance and predict esophageal contraction reserve.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Jan Tack, Ans Pauwels, Sabine Roman, Edoardo Savarino, Andre Smout
Summary: A European consensus was developed on the clinical application of esophageal high-resolution manometry (HRM), providing guidance on when to consider HRM, how to perform it, and how to interpret the results. Areas of uncertainty and lack of consensus were identified, particularly in terms of treatment implications, highlighting the need for future research in this area.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Isis K. Araujo, Sabine Roman, Marie Napoleon, Francois Mion
Summary: The study found that using solid food swallows (SFS) during esophageal motility assessment can improve diagnostic accuracy and is important for diagnosing clinically relevant disorders. The application of solid food swallows in HRM has a significant impact on changing diagnoses and can be widely used in daily clinical practice.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Frank Zerbib, Albert J. Bredenoord, Ronnie Fass, Peter J. Kahrilas, Sabine Roman, Edoardo Savarino, Daniel Sifrim, Michael Vaezi, Rena Yadlapati, C. Prakash Gyawali
Summary: The term refractory GERD is not as clear-cut as it may seem, with distinctions needed between different types of symptoms and objective evidence of GERD. Objective evaluation, including endoscopy and esophageal physiologic testing, is essential for understanding mechanisms of symptom generation and true refractory GERD. Attention should also be paid to potential contributors such as supragastric belching and rumination syndrome.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Rena Yadlapati, Peter J. Kahrilas, Mark R. Fox, Albert J. Bredenoord, C. Prakash Gyawali, Sabine Roman, Arash Babaei, Ravinder K. Mittal, Nathalie Rommel, Edoardo Savarino, Daniel Sifrim, Andre Smout, Michael F. Vaezi, Frank Zerbib, Junichi Akiyama, Shobna Bhatia, Serhat Bor, Dustin A. Carlson, Joan W. Chen, Daniel Cisternas, Charles Cock, Enrique Coss-Adame, Nicola de Bortoli, Claudia Defilippi, Ronnie Fass, Uday C. Ghoshal, Sutep Gonlachanvit, Albis Hani, Geoffrey S. Hebbard, Kee Wook Jung, Philip Katz, David A. Katzka, Abraham Khan, Geoffrey Paul Kohn, Adriana Lazarescu, Johannes Lengliner, Sumeet K. Mittal, Taher Omari, Moo In Park, Roberto Penagini, Daniel Pohl, Joel E. Richter, Jordi Serra, Rami Sweis, Jan Tack, Roger P. Tatum, Radu Tutuian, Marcelo F. Vela, Reuben K. Wong, Justin C. Wu, Yinglian Xiao, John E. Pandolfino
Summary: CCv4.0 is an updated classification scheme for esophageal motility disorders using HRM, developed by fifty-two international experts in seven subgroups over two years. Key updates include a more rigorous and expansive HRM protocol, refined definition of EGJOO, stricter criteria for ineffective esophageal motility, and description of baseline EGJ metrics. These changes aim to provide more standardized criteria for disorders of peristalsis and obstruction at the EGJ.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Kelli DeLay, John E. Pandolfino, Sabine Roman, C. Prakash Gyawali, Edoardo Savarino, Michael Tye, Alexander Kaizer, Rena Yadlapati
Summary: Supragastric belching (SGB) and rumination are behavioral disorders associated with proton pump inhibitor (PPI) non-response. This pilot study compared the diagnostic yield and inter-rater agreement for SGB and rumination using multichannel intraluminal impedance-pH (MII-pH) and post-prandial high-resolution impedance manometry (PPHRIM). Results showed that diagnostic accuracy and inter-rater agreement are higher for MII-pH than PPHRIM, and behavioral disorders are more frequently identified on PPHRIM. Clinical context is essential for accurate interpretation of the studies.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Review
Gastroenterology & Hepatology
Sabine Roman, Geoff Hebbard, Kee Wook Jung, Phil Katz, Radu Tutuian, Reuben Wong, Justin Wu, Rena Yadlapati, Daniel Sifrim
Summary: Distal esophageal spasm (DES) is characterized by premature contractions in the esophagus, often causing dysphagia or non-cardiac chest pain. Treatments for DES can be challenging, with endoscopic options like botulinum toxin and peroral endoscopic myotomy currently being evaluated. Further research is needed to understand the role of contractile vigor and lower esophageal sphincter hypercontractility in DES symptoms.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Letter
Gastroenterology & Hepatology
Jamila Lenz, Berenice Rault, Sabine Roman, Mathieu Pioche, Francois Mion
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
(2021)
Article
Otorhinolaryngology
Sabine Roman, Livia Anna Guadagnoli, Audrey Hastier, Estelle Becam, Meredith Ruth Ann Craven, John E. Pandolfino, Marie Napoleon, Dustin A. Carlson, Francois Mion, Tiffany Taft
Summary: The study found that the esophageal dysphagia questionnaire (BEDQ) is a valid clinical assessment tool in French, accurately reflecting the frequency and intensity of dysphagia in patients, and showing good correlation with other scoring tools. For patients undergoing examination, the BEDQ score is significantly higher in the dysphagia group compared to the GERD or other symptom groups.
Article
Gastroenterology & Hepatology
Barrett Rogers, Benjamin Rogers, Marzio Frazzoni, Edoardo Savarino, Sabine Roman, Daniel Sifrim, C. Prakash Gyawali
Summary: In pH-impedance studies, acidic reflux episodes in upright position with high proximal extent and longer acid clearance times have the highest concordance for identification by expert reviewers. Reflux episode identification may be influenced by reviewer opinions despite the availability of established criteria.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Article
Gastroenterology & Hepatology
Sabine Roman, Livia Anna Guadagnoli, Audrey Hastier, Estelle Becam, Meredith Ruth Ann Craven, Marie Napoleon, John E. Pandolfino, Dustin A. Carlson, Francois Mion, Tiffany Taft
Summary: The study validated a French version of the esophageal hypervigilance and anxiety scale (EHAS), showing good internal consistency and reliability. The EHAS score was consistent between groups, demonstrating its utility in assessing psychological processes in patients with esophageal disorders. Further research is needed to explore its application in patient management.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Pauline Riviere, Blandine Vauquelin, Emiliane Rolland, Chloe Melchior, Sabine Roman, Stanislas Bruley des Varannes, Francois Mion, Guillaume Gourcerol, Sylvie Sacher-Huvelin, Frank Zerbib
Summary: The study found that both a low FODMAP diet and usual dietary advice had similar but limited beneficial effects on symptoms in patients with PPI refractory GERD.
NEUROGASTROENTEROLOGY AND MOTILITY
(2021)
Article
Gastroenterology & Hepatology
Morgane Sallette, Jamila Lenz, Francois Mion, Sabine Roman
Summary: This study compared the frequency of motility disorders diagnosed with CCv3.0 and CCv4.0 and evaluated the severity of symptoms. The results showed that while the diagnoses remained mainly unchanged with both versions, CCv4.0 had a lower frequency of ineffective esophageal motility (IEM) compared to CCv3.0.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)