Article
Biochemistry & Molecular Biology
Akari Murata, Hirokazu Akiyama, Hiroyuki Honda, Kazunori Shimizu
Summary: Extracellular vesicles (EVs) released during exercise have health effects, but it is unclear if exercise increases the number of EVs released by skeletal muscle cells. This study used in vitro exercise models to investigate the effect of exercise on the quantity of EVs released from skeletal muscle cells. The results showed that tetanic contraction induced by 30 Hz electrical pulse stimulation increased the number of secreted EVs.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2023)
Article
Medicine, Research & Experimental
Yan Chen, Shuhui Zhang, Ying Li, Hui Yan, Ying Ba, Xuemin Wang, Ning Shi, Chengxia Liu
Summary: Gastric electrical stimulation (GES) improves the proliferation of interstitial cells of Cajal (ICC) and alters enteric neurons in diabetic rats, possibly through the 5-HT/5-HT2B signal pathway and the expression of glia cell line-derived neurotrophic factor (GDNF).
Review
Physiology
Gisele L. Cavalcante, Fernanda Brognara, Lucas Vaz de C. Oliveira, Renata M. Lataro, Marina de T. Durand, Aldeidia P. de Oliveira, Antonio Claudio L. da Nobrega, Helio C. Salgado, Joao Paulo J. Sabino
Summary: Systemic arterial hypertension and heart failure affect millions worldwide, with traditional approaches focusing on reducing sympathetic activity; however, studies suggest that improving parasympathetic function can be an effective treatment.
Article
Geriatrics & Gerontology
Janine Utz, Judith Berner, Luis Enrique Munoz, Timo Jan Oberstein, Johannes Kornhuber, Martin Herrmann, Juan Manuel Maler, Philipp Spitzer
Summary: The presence of synaptophysin-bearing microvesicles in the cerebrospinal fluid of patients with Alzheimer's disease may reflect the loss of synapses in the disease. Further studies are needed to explore the potential of using these microvesicles as a marker to assess the activity of Alzheimer's disease.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Oncology
Paul Girot, Nicolas Chapelle, Laetitia Aymeric, Anne Bessard, Alice Prigent, Yann Touchefeu, Christine Varon, Michel Neunlist, Emilie Duchalais, Tamara Matysiak-Budnik
Summary: Gastric cancer is a leading cause of cancer-related deaths globally. This study investigated the adhesion of gastric cancer cells to enteric neurons, and found that enteric neurons are a privileged site for gastric cancer cell adhesion, especially in diffuse-type gastric cancer. The adhesion was partially mediated by N-Cadherin, and blocking N-Cadherin significantly decreased the adhesion ability. These findings suggest a potential role of enteric neurons in the dissemination of gastric cancer cells.
Article
Multidisciplinary Sciences
K. L. Kozielski, A. Jahanshahi, H. B. Gilbert, Y. Yu, O. Erin, D. Francisco, F. Alosaimi, Y. Temel, M. Sitti
Summary: Research has shown that injectable magnetoelectric nanoelectrodes can wirelessly transmit electrical signals to the brain, modulating neurons and leading to behavioral changes in mice. This technology does not require genetic modification and could be a less invasive method for deep brain neuromodulation.
Article
Multidisciplinary Sciences
Eva-Maria Doelker, Stephan Lau, Maria Anne Bernhard, Jens Haueisen
Summary: The study aims to develop a wearable warning system using electrocutaneous stimulation. Various parameters such as pulse width, electrode size, and electrode position were investigated in 81 healthy volunteers to determine perception, attention, and intolerance thresholds. It was found that pulse width between 150 μs and 250 μs is suitable for electric warning wearables, and electrode size, inter-electrode distance, and electrode position are flexible parameters within practical limits.
SCIENTIFIC REPORTS
(2022)
Article
Gastroenterology & Hepatology
Bradley B. Barth, Lee Travis, Nick J. Spencer, Warren M. Grill
Summary: Electrical stimulation of the enteric nervous system can modify gastrointestinal transit by influencing colonic motor complexes. This study found that electrical stimulation can entrain myoelectric complexes in the smooth muscle of the colon, with timing parameters playing a crucial role in regulating the rate and duration of these complexes. Additionally, the absolute refractory period identified in the study provides valuable insight for designing neuromodulation strategies to treat colonic dysmotility.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Shihong Xu, Yu Deng, Jinping Luo, Enhui He, Yaoyao Liu, Kui Zhang, Yan Yang, Shengwei Xu, Longze Sha, Yilin Song, Qi Xu, Xinxia Cai
Summary: By using a high-performance microelectrode array, the study investigates and activates the learning and memory functions of neurons. Electrical stimulation can change the firing pattern of neurons and improve the correlation and synchrony of the networks.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Surgery
Doris Kim, Ryan Gedney, Shelby Allen, Haley Zlomke, Elizabeth Winter, John Craver, A. D. Pinnola, Will Lancaster, David Adams
Summary: This study retrospectively reviewed patients who underwent gastric electrical stimulation (GES) over a 10-year period and found that patients with gastroparesis had different clinical outcomes after GES therapy based on underlying etiology. Diabetic patients were more likely to continue therapy, while idiopathic patients were more likely to have the device removed.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Medicine, Research & Experimental
Yun Wang, Xinyu Xu, Lin Lin
Summary: The present study investigated the effects of prucalopride on intestinal motility in rats with diabetes mellitus by promoting the regeneration of the enteric nervous system. The results showed that prucalopride significantly shortened the colonic transit time in diabetic rats and increased the expression levels of Nestin, GFAP, SOX10, HuD, and PGP9.5.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
(2022)
Article
Neurosciences
Yuki Niimi, Jose Gomez-Tames, Toshiaki Wasaka, Akimasa Hirata
Summary: This study investigated the optimal parameters for selective stimulation of A delta- and C-fibers using a computational model and experimental results. The results showed that different sensations could be elicited by selectively stimulating different fibers by adjusting the pulse counts and frequencies. The computational model revealed that terminal axon thickness was the most important biophysical factor affecting perception thresholds.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Cell Biology
J. H. Lautaoja, D. C. Turner, A. P. Sharples, R. Kivela, S. Pekkala, J. J. Hulmi, L. Yla-Outinen
Summary: The number of studies using skeletal muscle cell culture models to study exercise in vitro is increasing rapidly. Omics approaches, such as transcriptomics, proteomics, and metabolomics, have been used to analyze the molecular responses to exercise mimicking stimuli in cultured myotubes. Electrical pulse stimulation and mechanical stretch are the most commonly used methods to mimic exercise in vitro. This mini-review provides an up-to-date overview of the 2-D and 3-D models and the use of omics approaches to study the molecular response to exercise in vitro.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Yervant Ichkhanian, Mohammad A. Al-Haddad, Chelsea C. Jacobs, Alexander Schlachterman, Juliana Yang, Andrew Canakis, Raymond Kim, Arcelia Guerson-Gil, Lionel S. D'Souza, Eva Alsheik, Brian D. Ginnebaugh, Mouen A. Khashab, Tobias Zuchelli, Kellie McFarlin, Cyrus Piraka
Summary: In patients with refractory symptoms after GNS, G-POEM can be a reasonable salvage therapy to provide further symptomatic relief, with evidence of a potential additive effect of both G-POEM and GNS.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Chemistry, Analytical
Hsin-Yi Tsai, Yu-Hsuan Lin, Kuo-Cheng Huang, Ching-Ching Yang, Chun-Han Chou, Liang-Chieh Chao
Summary: Viruses and bacteria can spread rapidly and have serious health effects. In this study, electrical stimulation was used to reduce the infectivity of a virus (coronavirus 229E) and two types of bacteria (Escherichia coli and Staphylococcus aureus). The experimental results showed significant inhibition of coronavirus 229E activity with direct-current pulse stimulation, and a rapid reduction in E. coli activity with alternating-current pulse stimulation. Additionally, a self-powered electrical stimulation device was developed for inhibiting viral and bacterial activities.
Article
Optics
Chao Chen, Xiuguo Chen, Sheng Sheng, Zhongwen Xia, Jiacheng Shi, Wen Qiao, Shiyuan Liu
Summary: In this study, a home-made imaging Mueller matrix ellipsometer (IMME) was proposed to monitor the sidewall tilting of pixelated nanogratings. Through the combination of Mueller matrix elements, the tilting angle can be quickly and qualitatively identified for on-line quality monitoring of the device. By inversely calculating the Mueller matrix, the value of the tilting can be accurately and quantitatively obtained to meet the demands of the device design. It is expected that this method can provide guidance for the identification and detection of tilting in 3D display elements based on pixelated gratings.
Article
Materials Science, Multidisciplinary
Chunfu Guo, Yating Shi, Huaxi Wu, Yabo Xiang, Weiqi Li, Chuanwei Zhang, Shiyuan Liu
Summary: Optical scatterometry is widely used for nanostructure metrology in integrated circuit. This paper proposes a combination of library search and Levenberg-Marquardt algorithm to solve the problem. Simulations and experiments demonstrate that the proposed method is accurate and significantly faster than previous methods.
Article
Chemistry, Multidisciplinary
Honggang Gu, Zhengfeng Guo, Liusheng Huang, Mingsheng Fang, Shiyuan Liu
Summary: In this study, a quantitative strategy is proposed to systematically identify the critical point optical transitions of 2D semiconductors by combining spectroscopic ellipsometry and DFT calculations. Optical functions and critical points are determined by spectroscopic ellipsometry and connected to DFT band structure and projected density of states. The combination of spectroscopic ellipsometry and DFT provides a powerful tool to investigate the critical point optical transitions.
Article
Chemistry, Multidisciplinary
Zhengfeng Guo, Honggang Gu, Yali Yu, Zhongming Wei, Shiyuan Liu
Summary: Optical anisotropy in SnSe is utilized to design broadband and incident-angle-modulation near-infrared polarizers, with high modulation efficiency and no energy consumption. The broadband polarizer has a bandwidth of 324 nm and an average extinction ratio above 23 dB, while the incident-angle-modulation polarizer dynamically and reversibly modulates its working wavelength with a maximum extinction ratio of 71 dB. The proposed design opens up possibilities for mass-production and integration of polarizing optical components based on low-symmetry materials.
Article
Optics
Jinsong Zhang, Jiamin Liu, Jinlong Zhu, Hao Jiang, Shiyuan Liu
Summary: In this paper, an angle-resolved scatterometer capable of detecting multi-order diffracted light in a single measurement is proposed. An in-situ calibration method for the objective lens's polarization effects is also introduced. By considering the polarization effect of the objective lens, significant improvements in accuracy and repeatability precision can be achieved in the metrology of film thickness and grating topography parameters.
Article
Optics
Yaobin Feng, Zhiyang Song, Jiaman Liu, Zhiqin LI, Feng Yang, Hao Jiang, Shiyuan Liu
Summary: This paper proposes a method to evaluate the pattern coverage before obtaining any metrology data and constructs evaluation metrics. Experimental results show a positive correlation between these metrics and lithographic model accuracy. This method can improve the efficiency of OPC model building and is beneficial to the development process of the whole OPC recipe.
Article
Optics
Xiuguo Chen, Jing Hu, Wenlong Chen, Shilong Yang, Yifu Wang, Shiyuan Liu
Summary: This letter proposes a multi-spectral diffraction-based overlay (DBO) metrology method that utilizes the linear relation between overlay errors and combinations of Mueller matrix elements. The proposed approach enables snapshot and direct measurement of overlay errors over a wide spectral range without the need for rotating or active polarization components.
Article
Engineering, Multidisciplinary
Tianjuan Yang, Xiuguo Chen, Shuo Liu, Jiahao Zhang, Shiyuan Liu
Summary: This study proposes a measurement configuration optimization (MCO) method for optical scatterometry, which combines error propagation theory and condition-number-based error estimation technique to select an optimal or suboptimal combination of measurement conditions for higher measurement accuracy. The method is demonstrated on a multi-wavelength Mueller matrix scatterometry and shows good agreement in fitting results. This method provides an alternate solution to evaluate the MCO problem in optical scatterometry and other measurement scenarios.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2023)
Article
Optics
Chuangchuang Chen, Jiamin Liu, Jinlong Zhu, Honggang Gu, Shiyuan Liu
Summary: Reflection ptychography is a lens-free computational imaging technology that captures distorted diffracted patterns using a coherent beam illuminated to a specimen inclined to the optical axis. The distortion caused by the non-coplanar scattering geometry disrupts the standard ptychographic reconstruction algorithms. We propose and analyze an axial distance calibration approach to improve the reconstructed resolution in reflection ptychography.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Optics
Li Liu, Wenjie Li, Lei Zhong, Honggang Gu, Shiyuan Liu
Summary: This paper proposes an adaptive noise-blind-separation (aNBS) algorithm to deal with mixed noises of different types in ptychography. The algorithm introduces virtual probes of different wavelengths to capture noise energies and adaptively separates the mixed noises in ptychography. The proposed algorithm can separate coherent diffraction signals and noises without additional constraints or assumptions.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Optics
Pinxuan He, Jiamin Liu, Honggang Gu, Jinlong Zhu, Hao Jiang, Shiyuan Liu
Summary: A method based on the modified Born series (MBS) is introduced for efficiently and accurately calculating the near field of extreme ultraviolet (EUV) masks with complex patterns. The MBS method is much faster than the finite-difference time-domain method while maintaining comparable accuracy.
Article
Optics
Zhou Jiang, Song Zhang, Hao Jiang, Shiyuan Liu
Summary: This paper proposes a calibration method to compensate for the field-of-view effect of waveplates installed in instruments, and verifies the effectiveness of the method through experiments. The results show that the proposed method significantly improves the precision and accuracy of film thickness measurement, reduces the assembly difficulty of optical systems, and improves their accuracy and stability.
Article
Optics
Jiamin Liu, Wenqi Gong, Lei Li, Song Zhang, Jinlong Zhu, Rong Chen, Hao Jiang, Shiyuan Liu
Summary: This paper presents an in-situ characterization method based on Mueller-matrix ellipsometry for investigating the longitudinal MO Kerr effects occurring in subwavelength thick ferromagnetic films. The proposed method allows reliable capture of the weak MO Kerr response signal of the ferromagnetic films with high repeatability precision better than 0.0002.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Zhengfeng Guo, Honggang Gu, Mingsheng Fang, Lei Ye, Shiyuan Liu
Summary: Tellurene's giant in-plane optical anisotropy can be quantitatively evaluated using imaging Mueller matrix spectroscopic ellipsometry and first-principles calculations, and it is connected to its low-symmetry lattice structure and electrical anisotropy. This work provides a general and quantitative way to explore optical anisotropy and helps in understanding the relationship between lattice structure and optical anisotropy, thus promoting the development of polarization-sensitive optical applications.
Article
Materials Science, Multidisciplinary
Mingsheng Fang, Honggang Gu, Baokun Song, Zhengfeng Guo, Shiyuan Liu
Summary: This research investigates the thickness scaling effects on the optical conductivity of WSe2 by using spectroscopic ellipsometry and the classical slab model. The results reveal that the central energies of low-energy feature peaks decrease with increasing thickness, while the central energies of high-energy feature peaks exhibit a blueshift followed by a redshift with thickness. These findings are crucial for understanding the complex optical properties of WSe2.
ADVANCED PHOTONICS RESEARCH
(2022)
