Article
Clinical Neurology
Theodoros Constantinidis, Chryssa Arvaniti, Nikolaos Fakas, Jobst Rudolf, Evangelos Kouremenos, Ermioni D. Giannouli, Dimos Mitsikostas, Hellenic Headache Society
Summary: This study aimed to estimate the prevalence and burden of medication overuse headache in a representative sample of the Greek population. Results showed that the prevalence of medication overuse headache in Greece was 0.7%, with a higher proportion in females. The impact on work performance and productivity was significant. Medication overuse headache is a serious socio-economic health problem that requires immediate health policy planning.
Article
Behavioral Sciences
Simona Guerzoni, Carlo Baraldi, Flavia Lo Castro, Maria Michela Cainazzo, Luca Pani
Summary: This study aims to explore the effectiveness and safety of galcanezumab in the treatment of chronic migraine with medication overuse-headache. The results showed that galcanezumab significantly reduced the number of migraine days per month, the frequency and duration of painkiller usage, and improved the impact of headache on patients' daily life. It was also found that patients with higher baseline impairment and more failed preventive treatments may have less benefit from galcanezumab. Overall, galcanezumab is effective and safe for the treatment of chronic migraine with medication overuse-headache.
BRAIN AND BEHAVIOR
(2023)
Article
Clinical Neurology
Todd J. Schwedt, Joseph G. Hentz, Soma Sahai-Srivastava, Nicole M. Spare, Vincent T. Martin, Christina Treppendahl, Kathleen Digre, Nathan L. Bennett, Marius Birlea, David Watson, Natalia Murinova, Teri Robert, David W. Dodick
Summary: The study described headache characteristics, medication use, disability, and quality of life in patients with chronic migraine (CM) and medication overuse headache (MOH) from the United States. Findings showed a significant burden on patients with CM and MOH, with higher headache frequency associated with greater impact on functioning, pain interference, and quality of life.
Article
Clinical Neurology
Yen-Feng Wang, Chia-Chun Yu, Ai Seon Kuan, Shih-Pin Chen, Shuu-Jiun Wang
Summary: The study found that in chronic migraine patients, comorbid medication-overuse headache (MOH) is associated with an increased risk of suicidal ideation and prior suicide attempt.
JOURNAL OF HEADACHE AND PAIN
(2021)
Article
Clinical Neurology
Niushen Zhang, Yohannes W. Woldeamanuel
Summary: The study revealed a significant association between cannabis use and an increased prevalence of medication overuse headache in patients with chronic migraine. A bidirectional association between cannabis and opioid use was also observed.
Article
Clinical Neurology
Abouch V. V. Krymchantowski, Carla Jevoux, Ana Gabriela Krymchantowski, Raimundo Pereira Silva-Neto
Summary: Anti-CGRP monoclonal antibodies added to conventional treatments can effectively reduce the frequency of headaches and the use of symptomatic medications for patients with chronic migraine and medication overuse headache.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Michael J. Marmura, Hans-Christoph Diener, Robert P. Cowan, Stewart J. Tepper, Merle L. Diamond, Amaal J. Starling, Joe Hirman, Lahar Mehta, Thomas Brevig, Roger Cady
Summary: In patients with chronic migraine and medication-overuse headache treated with eptinezumab in the PROMISE-2 study, there was a significant reduction in the use of acute headache medication and a substantial proportion of patients did not meet diagnostic thresholds for either CM or MOH throughout the entire treatment period.
Article
Clinical Neurology
Hong-Kyun Park, Min Kyung Chu, Sun-Young Oh, Heui-Soo Moon, Tae-Jin Song, Mi Ji Lee, Jin-Ju Kang, Yooha Hong, Soo-Jin Cho
Summary: This study enrolled 229 patients with medication overuse headache in Korea, revealing that patients commonly experienced chronic headaches and medication overuse, severely impacting daily functioning. A significant proportion of patients exhibited moderate to severe depression and anxiety, while the use of preventive treatments increased during the study period.
Article
Biology
Jacob Genizi, Morya Shnaider, Liat Yaniv, Nogah C. Kerem, Keren Nathan, Irina Chistyakov
Summary: Medication overuse headaches are common in children with chronic headaches, particularly those with tension-type headaches (TTH). They appear to be more pronounced in TTH patients compared to migraine sufferers, and have a higher prevalence among females.
Article
Clinical Neurology
Jakub Radziwon, Przemyslaw Waszak
Summary: This internet-based study found that web searching for headache disorders shows a circannual rhythm, with increased interest during spring and autumn. This suggests that many patients experience seasonal variations in their headaches.
Article
Clinical Neurology
Marcella Curone, Vincenzo Tullo, Henri Albert Didier, Gennaro Bussone
Summary: Monoclonal antibodies inhibiting CGRP are effective in reducing monthly headache days in migraine patients with medication overuse headache.
NEUROLOGICAL SCIENCES
(2022)
Article
Clinical Neurology
David W. Dodick, Erin G. Doty, Sheena K. Aurora, Dustin D. Ruff, Virginia L. Stauffer, Jakub Jedynak, Yan Dong, Eric M. Pearlman
Summary: The study demonstrates that galcanezumab is effective in preventing episodic and chronic migraine in patients with acute medication overuse, significantly reducing the number of monthly migraine days and medication overuse rates compared to placebo.
Article
Medicine, General & Internal
Yen-Feng Wang, Yi-Shiang Tzeng, Chia-Chun Yu, Yu-Hsiang Ling, Shih-Pin Chen, Kuan-Lin Lai, Shuu-Jiun Wang
Summary: Dependence behaviors were characterized in patients with medication-overuse headache (MOH) using the Leeds dependence questionnaire (LDQ), and the clinical utility of LDQ in the diagnosis of MOH was determined. The results showed a positive correlation between LDQ scores and the monthly frequency of acute medication use. MOH patients had higher LDQ scores, and an LDQ score of >= 7 was found to be useful in the detection of MOH.
Article
Clinical Neurology
Todd J. Schwedt, Soma Sahai-Srivastava, Natalia Murinova, Marius Birlea, Zubair Ahmed, Kathleen Digre, Kristina Lopez, William Mullally, Maike Tiede Blaya, Karly Pippitt, Fred Michael Cutrer, Justin DeLange, Howard Schecht, Paul Rizzoli, Judy Lane, John Wald, Melissa M. Cortez, Vincent T. Martin, Nicole M. Spare, Joseph G. Hentz, Teri Robert, David W. Dodick
Summary: Chronic migraine with medication overuse leads to severe negative consequences on an individual's life, with depression symptoms being the strongest predictor of pain interference and headache impact.
Article
Clinical Neurology
Maria Michela Cainazzo, Carlo Baraldi, Anna Ferrari, Flavia Lo Castro, Luca Pani, Simona Guerzoni
Summary: This study retrospectively analyzed data from 81 patients with chronic migraine and medication overuse headache who were treated with erenumab. The results showed that erenumab was effective in reducing headache frequency and analgesic consumption over a period of 1 year, significantly improving symptoms in patients.
NEUROLOGICAL SCIENCES
(2021)
Article
Clinical Neurology
Kjersti Grotta Vetvik, Jurate Saltyte Benth, E. Anne MacGregor, Christofer Lundqvist, Michael Bjorn Russell
Article
Clinical Neurology
Marianne Moe Halvorsen, Jocelyne Clench-Aas, Grete Patil, Christofer Lundqvist
Article
Primary Health Care
Jan C. Frich, Espen Saxhaug Kristoffersen, Christofer Lundqvist
BRITISH JOURNAL OF GENERAL PRACTICE
(2014)
Article
Clinical Neurology
Kjersti G. Vetvik, E. Anne MacGregor, Christofer Lundqvist, Michael B. Russell
Article
Clinical Neurology
Kjersti Aaseth, Ragnhild Berling Grande, Christofer Lundqvist, Michael Bjorn Russell
JOURNAL OF HEADACHE AND PAIN
(2014)
Article
Clinical Neurology
Kjersti Grotta Vetvik, E. Anne MacGregor, Christofer Lundqvist, Michael Bjorn Russell
JOURNAL OF HEADACHE AND PAIN
(2014)
Article
Clinical Neurology
Christofer Lundqvist, Antonie Giaever Beiske, Ola Reiertsen, Ivar Sonbo Kristiansen
JOURNAL OF NEUROLOGY
(2014)
Article
Clinical Neurology
Espen Saxhaug Kristoffersen, Jorund Straand, Kjersti Grotta Vetvik, Jurate Saltyte Benth, Michael Bjorn Russell, Christofer Lundqvist
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2015)
Article
Psychiatry
Espen Saxhaug Kristoffersen, Christofer Lundqvist, Michael Bjorn Russell
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2019)
Article
Clinical Neurology
Siri Hylleraas Bo, Christofer Lundqvist
JOURNAL OF NEUROLOGY
(2020)
Article
Critical Care Medicine
Viktoriia Chaban, Espen R. Nakstad, Henrik Staer-Jensen, Camilla Schjalm, Ingebjorg Seljeflot, Jarle Vaage, Christofer Lundqvist, Jurate Altyte Benth, Kjetil Sunde, Tom Eirik Mollnes, Geir O. Andersen, Soren Erik Pischke
Summary: The study revealed that complement system activation in out-of-hospital cardiac arrest patients, reflected by sC5b-9 at admission, was associated with poor outcomes. Endothelial cell activation markers were also elevated in patients with poor outcomes, particularly sE-selectin and thrombomodulin, which correlated with sCD14 and sC5b-9/C3bc, respectively.
Article
Clinical Neurology
Maria Torheim Bjelkaroy, Socheat Cheng, Tahreem Ghazal Siddiqui, Jurate Saltyte Benth, Ramune Grambaite, Espen Saxhaug Kristoffersen, Christofer Lundqvist
Summary: For older patients with long-term use of CNSD medications, there is a strong positive association between pain intensity and prolonged use of these medications. The most common pain sites were the back and lower extremities, with patients experiencing pain in these areas reporting higher overall pain intensity.
SCANDINAVIAN JOURNAL OF PAIN
(2022)
Article
Multidisciplinary Sciences
Tahreem Ghazal Siddiqui, Maria Torheim Bjelkaroy, Socheat Cheng, Espen Saxhaug Kristoffersen, Ramune Grambaite, Christofer Lundqvist
Summary: The study found that older patients with reduced cognitive function and prolonged use of Central Nervous System Depressants (CNSD) during hospitalization had higher mortality rates two years after discharge.
Article
Medicine, General & Internal
Tahreem Ghazal Siddiqui, Socheat Cheng, Michael Gossop, Espen Saxhaug Kristoffersen, Ramune Grambaite, Christofer Lundqvist
Review
Pharmacology & Pharmacy
Espen Saxhaug Kristoffersen, Christofer Lundqvist
THERAPEUTIC ADVANCES IN DRUG SAFETY
(2014)