The GABA Synapse as a Target for Antiepileptic Drugs: A Historical Overview Focused on GABA Transporters

Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile

(2013) Bolette Kragholm et al.   BIOCHEMICAL PHARMACOLOGY

Stiripentol in Dravet syndrome: Results of a retrospective U.S. study

(2013) Elaine C. Wirrell et al.   EPILEPSIA

Selective mGAT2 (BGT-1) GABA Uptake Inhibitors: Design, Synthesis, and Pharmacological Characterization

(2013) Stine B. Vogensen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?

(2013) Joeri Van Liefferinge et al.   Frontiers in Cellular Neuroscience

Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA

(2013) Arne Schousboe et al.   Frontiers in Endocrinology

Molecular pathways controlling inhibitory receptor expression

(2012) Heidi L. Grabenstatter et al.   EPILEPSIA

Glutamate and GABA synthesis, release, transport and metabolism as targets for seizure control

(2012) Nicole M. Rowley et al.   NEUROCHEMISTRY INTERNATIONAL

Concentrations of Stiripentol in Children and Adults With Epilepsy

(2012) Theodor W. May et al.   THERAPEUTIC DRUG MONITORING

The effects of stiripentol on GABAA receptors

(2011) Janet L. Fisher   EPILEPSIA

Deletion of the betaine–GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

(2011) A.C. Lehre et al.   EPILEPSY RESEARCH

Interactions between modulators of the GABAA receptor: Stiripentol and benzodiazepines

(2011) Janet L. Fisher   EUROPEAN JOURNAL OF PHARMACOLOGY

Selective GABA Transporter Inhibitors Tiagabine and EF1502 Exhibit Mechanistic Differences in Their Ability to Modulate the Ataxia and Anticonvulsant Action of the Extrasynaptic GABAA Receptor Agonist Gaboxadol

(2011) K. K. Madsen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Synaptic and extrasynaptic GABA transporters as targets for anti-epileptic drugs

(2009) Karsten K. Madsen et al.   JOURNAL OF NEUROCHEMISTRY

Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs

(2009) Karsten K. Madsen et al.   PHARMACOLOGY & THERAPEUTICS

The anti-convulsant stiripentol acts directly on the GABAA receptor as a positive allosteric modulator

(2008) Janet L. Fisher   NEUROPHARMACOLOGY