Roles of Glutamine Synthetase Inhibition in Epilepsy

Why does the brain (not) have glycogen?

(2011) Mauro DiNuzzo et al.   BIOESSAYS

The role of the glutathione system in seizures induced by diphenyl diselenide in rat pups

(2011) Marina Prigol et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Redistribution of astrocytic glutamine synthetase in the hippocampus of chronic epileptic rats

(2011) Ismini E. Papageorgiou et al.   GLIA

Astrocytic energy metabolism and glutamate formation — relevance for 13C-NMR spectroscopy and importance of cytosolic/mitochondrial trafficking

(2011) Leif Hertz   MAGNETIC RESONANCE IMAGING

Natural course of glutamine synthetase deficiency in a 3year old patient

(2011) Johannes Häberle et al.   MOLECULAR GENETICS AND METABOLISM

Roles of glutamine in neurotransmission

(2011) Jan Albrecht et al.   Neuron Glia Biology

Contribution of astrocyte glycogen stores to progression of spreading depression and related events in hippocampal slices

(2011) J.L. Seidel et al.   NEUROSCIENCE

13C MRS studies of neuroenergetics and neurotransmitter cycling in humans

(2011) Douglas L. Rothman et al.   NMR IN BIOMEDICINE

Neurotransmitter transporters expressed in glial cells as regulators of synapse function

(2010) Volker Eulenburg et al.   BRAIN RESEARCH REVIEWS

Do astrocytes really exocytose neurotransmitters?

(2010) Nicola B. Hamilton et al.   NATURE REVIEWS NEUROSCIENCE

Astrocyte glutamine synthetase: Importance in hyperammonemic syndromes and potential target for therapy

(2010) Saul W. Brusilow et al.   Neurotherapeutics

Epilepsy, Regulation of Brain Energy Metabolism and Neurotransmission

(2009) Jean-Francois Cloix et al.   CURRENT MEDICINAL CHEMISTRY

The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats

(2009) Yue Wang et al.   EXPERIMENTAL NEUROLOGY

Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression

(2009) Adolfo Sequeira et al.   PLoS One

Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats

(2008) T. Eid et al.   BRAIN

System A Transporter SAT2 Mediates Replenishment of Dendritic Glutamate Pools Controlling Retrograde Signaling by Glutamate

(2008) Monica Jenstad et al.   CEREBRAL CORTEX

Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients

(2008) Idil Cavus et al.   EPILEPSIA

Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design

(2007) Wojciech W. Krajewski et al.   JOURNAL OF MOLECULAR BIOLOGY