Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study

Relationship between whole-body tumor burden, clinical phenotype, and quality of life in patients with neurofibromatosis

(2014) Vanessa L. Merker et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas

(2014) B. C. Widemann et al.   NEURO-ONCOLOGY

Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas

(2014) Brigitte C. Widemann et al.   PEDIATRIC BLOOD & CANCER

Sirolimus Improves Pain in NF1 Patients With Severe Plexiform Neurofibromas

(2014) C. Hua et al.   PEDIATRICS

Patient-reported outcomes in neurofibromatosis and schwannomatosis clinical trials

(2013) P. L. Wolters et al.   NEUROLOGY

Population Pharmacokinetics of Sirolimus in Pediatric Patients With Neurofibromatosis Type 1

(2013) Jeffrey R. Scott et al.   THERAPEUTIC DRUG MONITORING

Deconvoluting mTOR biology

(2012) Jason D. Weber et al.   CELL CYCLE

Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial

(2012) Kent A Robertson et al.   LANCET ONCOLOGY

Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice

(2012) J. Halloran et al.   NEUROSCIENCE

18-fluorodeoxyglucose-positron emission tomography (FDG-PET) evaluation of nodular lesions in patients with neurofibromatosis type 1 and plexiform neurofibromas (PN) or malignant peripheral nerve sheath tumors (MPNST)

(2012) Holly Meany et al.   PEDIATRIC BLOOD & CANCER

Quantitative Assessment of Whole-Body Tumor Burden in Adult Patients with Neurofibromatosis

(2012) Scott R. Plotkin et al.   PLoS One

Adult hippocampal neurogenesis and related neurotrophic factors

(2011) Eu-Gene Lee et al.   BMB Reports

Preclinicalin vivoevaluation of rapamycin in human malignant peripheral nerve sheath explant xenograft

(2009) Priya Bhola et al.   INTERNATIONAL JOURNAL OF CANCER

Characteristics of children enrolled in treatment trials for NF1-related plexiform neurofibromas

(2009) A. Kim et al.   NEUROLOGY

Immunosuppression Using the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus: Pilot Study Shows Significant Cognitive and Affective Improvement

(2009) U.E. Lang et al.   TRANSPLANTATION PROCEEDINGS

Preclinical Cancer Therapy in a Mouse Model of Neurofibromatosis-1 Optic Glioma

(2008) B. Hegedus et al.   CANCER RESEARCH

Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors

(2008) G. Johansson et al.   MOLECULAR CANCER THERAPEUTICS