Identifying dysfunctional miRNA-mRNA regulatory modules by inverse activation, cofunction, and high interconnection of target genes: A case study of glioblastoma

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

A novel computational framework for simultaneous integration of multiple types of genomic data to identify microRNA-gene regulatory modules

(2011) Shihua Zhang et al.   BIOINFORMATICS

Identification of microRNA-mRNA modules using microarray data

(2011) Vivek Jayaswal et al.   BMC GENOMICS

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

(2011) Konstantinos J Mavrakis et al.   NATURE GENETICS

Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer

(2011) M Musumeci et al.   ONCOGENE

Identifying functional miRNA–mRNA regulatory modules with correspondence latent dirichlet allocation

(2010) Bing Liu et al.   BIOINFORMATICS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

The Role of Notch Signaling Pathway in Epithelial-Mesenchymal Transition (EMT) During Development and Tumor Aggressiveness

(2010) Zhiwei Wang et al.   CURRENT DRUG TARGETS

microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma

(2010) Julja Burchard et al.   Molecular Systems Biology

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

MiRNA–miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features

(2010) Juan Xu et al.   NUCLEIC ACIDS RESEARCH

Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells

(2010) F Yu et al.   ONCOGENE

MiR-30 family and EMT in human fetal pancreatic islets

(2010) Sabire Özcan   Islets

IDENTIFYING CO-REGULATING MICRORNA GROUPS

(2010) JIYUAN AN et al.   Journal of Bioinformatics and Computational Biology

Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers

(2009) Xinxia Peng et al.   BMC GENOMICS

Clustered microRNAs' coordination in regulating protein-protein interaction network

(2009) Xiongying Yuan et al.   BMC Systems Biology

Identification and Functional Characterization of microRNAs Involved in the Malignant Progression of Gliomas

(2009) Bastian Malzkorn et al.   BRAIN PATHOLOGY

MiR-15a and MiR-16 Control Bmi-1 Expression in Ovarian Cancer

(2009) R. Bhattacharya et al.   CANCER RESEARCH

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

(2009) Junfang Ji et al.   HEPATOLOGY

MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells

(2009) Teng Xu et al.   HEPATOLOGY

Discovery of functional miRNA–mRNA regulatory modules with computational methods

(2009) Bing Liu et al.   JOURNAL OF BIOMEDICAL INFORMATICS

miR-21 and 221 upregulation and miR-181b downregulation in human grade II–IV astrocytic tumors

(2009) Alfredo Conti et al.   JOURNAL OF NEURO-ONCOLOGY

DIANA-microT web server: elucidating microRNA functions through target prediction

(2009) M. Maragkakis et al.   NUCLEIC ACIDS RESEARCH

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis

(2009) Haihao Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of microRNA regulatory modules in Arabidopsis via a probabilistic graphical model

(2008) Je-Gun Joung et al.   BIOINFORMATICS

hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

(2008) Lei Shi et al.   BRAIN RESEARCH

MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G

(2008) Yang Chen et al.   CANCER LETTERS

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

(2008) B. Kefas et al.   CANCER RESEARCH

miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells

(2008) Lin Xia et al.   INTERNATIONAL JOURNAL OF CANCER

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

Human Protein Reference Database--2009 update

(2008) T. S. Keshava Prasad et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

(2008) F. Pichiorri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA