Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways

Redox signaling loops in the unfolded protein response

(2012) Arisa Higa et al.   CELLULAR SIGNALLING

Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide

(2012) Stella Sun et al.   JOURNAL OF NEURO-ONCOLOGY

Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells

(2012) Caroline Happold et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of CLIC4 Enhances Autophagy and Triggers Mitochondrial and ER Stress-Induced Apoptosis in Human Glioma U251 Cells under Starvation

(2012) Jiateng Zhong et al.   PLoS One

Stressed to Death: Targeting Endoplasmic Reticulum Stress Response Induced Apoptosis in Gliomas

(2011) Guyla G. Johnson et al.   CURRENT PHARMACEUTICAL DESIGN

Preclinical Development of Novel Anti-Glioma Drugs Targeting the Endoplasmic Reticulum Stress Response

(2011) Axel H. Schonthal et al.   CURRENT PHARMACEUTICAL DESIGN

Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines

(2011) Stella Sun et al.   JOURNAL OF NEURO-ONCOLOGY

The nonsteroidal anti-inflammatory drug celecoxib suppresses the growth and induces apoptosis of human glioblastoma cells via the NF-κB pathway

(2011) Gangadhara Reddy Sareddy et al.   JOURNAL OF NEURO-ONCOLOGY

Protein disulfide isomerase knockdown-induced cell death is cell-line-dependent and involves apoptosis in MCF-7 cells

(2011) Tomoyo Hashida et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Overexpression of GRP78 protects glial cells from endoplasmic reticulum stress

(2011) Kaori Suyama et al.   NEUROSCIENCE LETTERS

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Bacitracin is not a specific inhibitor of protein disulfide isomerase

(2010) Anna-Riikka Karala et al.   FEBS Journal

Acquisition of Temozolomide Chemoresistance in Gliomas Leads to Remodeling of Mitochondrial Electron Transport Chain

(2010) Claudia R. Oliva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomics of Hepatocellular Carcinoma: Serum Vimentin As a Surrogate Marker for Small Tumors (≤2 cm)

(2010) Stella Sun et al.   JOURNAL OF PROTEOME RESEARCH

Hypoxia and the Malignant Glioma Microenvironment: Regulation and Implications for Therapy

(2010) L. Oliver et al.   Current Molecular Pharmacology

Protein Disulfide Isomerase: A Critical Evaluation of Its Function in Disulfide Bond Formation

(2009) Feras Hatahet et al.   ANTIOXIDANTS & REDOX SIGNALING

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib

(2009) J. Kern et al.   BLOOD

Acquired Resistance to Combination Treatment with Temozolomide and ABT-888 Is Mediated by Both Base Excision Repair and Homologous Recombination DNA Repair Pathways

(2009) X. Liu et al.   MOLECULAR CANCER RESEARCH

Increasing Melanoma Cell Death Using Inhibitors of Protein Disulfide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress

(2008) P. E. Lovat et al.   CANCER RESEARCH

Phase I Trial Using Proteasome Inhibitor Bortezomib and Concurrent Temozolomide and Radiotherapy for Central Nervous System Malignancies

(2008) Gregory J. Kubicek et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS