Targeting Notch pathway induces growth inhibition and differentiation of neuroblastoma cells

Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane

(2010) Mariagioia Zampagni et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53

(2009) Rajiv Janardhanan et al.   BIOCHEMICAL PHARMACOLOGY

Inhibition of γ-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells

(2009) S Rasul et al.   BRITISH JOURNAL OF CANCER

Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells

(2009) S. S. Rao et al.   CANCER RESEARCH

Hypoxia-Regulated Delta-like 1 Homologue Enhances Cancer Cell Stemness and Tumorigenicity

(2009) Y. Kim et al.   CANCER RESEARCH

Notch signalling in cancer stem cells

(2009) Victoria Bolós et al.   Clinical & Translational Oncology

The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain

(2009) Xudong Zhao et al.   DEVELOPMENTAL CELL

Notch activation induces neurite remodeling and functional modifications in SH-SY5Y neuronal cells

(2009) Giulia Ferrari-Toninelli et al.   Developmental Neurobiology

New therapeutic targets for the treatment of high-risk neuroblastoma

(2009) Lars M. Wagner et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis

(2008) Y. Funahashi et al.   CANCER RESEARCH

Activity of γ -Secretase on Substrates Other than APP

(2008) Alberto D.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

In vitro validation of  -secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia

(2008) K. De Keersmaecker et al.   HAEMATOLOGICA

γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

(2008) Pedro J Real et al.   NATURE MEDICINE

Microtubule stabilizing effect of notch activation in primary cortical neurons

(2008) G. Ferrari-Toninelli et al.   NEUROSCIENCE

Rational targeting of Notch signaling in cancer

(2008) P Rizzo et al.   ONCOGENE

Notch signaling regulates tumor angiogenesis by diverse mechanisms

(2008) J Dufraine et al.   ONCOGENE

High risk neuroblastoma: A persistent therapeutic challenge

(2008) Alberto Garaventa et al.   PEDIATRIC BLOOD & CANCER

Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation

(2008) C. K. Hahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

(2008) C. Sahlgren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein

(2008) Ting Yang et al.   Molecular Brain

The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta–Notch pathway in neuroblastoma

(2007) Ingrid Revet et al.   EXPERIMENTAL CELL RESEARCH

Progenitor cell maintenance and neurogenesis in sympathetic ganglia involves Notch signaling

(2007) Konstantina Tsarovina et al.   MOLECULAR AND CELLULAR NEUROSCIENCE