Nrf2 implicated as a novel therapeutic target for renal regeneration after acute kidney injury

Nrf2 signalling promotes ex vivo tubular epithelial cell survival and regeneration via murine double minute (MDM)-2

(2013) Jan H. Hagemann et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Nrf2–keap1 system versus NF-κB: The good and the evil in chronic kidney disease?

(2012) Liliana Magnago Pedruzzi et al.   BIOCHIMIE

Crosstalk between Nrf2 and the proteasome: Therapeutic potential of Nrf2 inducers in vascular disease and aging

(2012) Sarah J. Chapple et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice

(2012) Shrikant R. Mulay et al.   KIDNEY INTERNATIONAL

Family Portrait

(2011) Paola Romagnani   AMERICAN JOURNAL OF PATHOLOGY

Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2

(2011) Aram You et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1 

(2011) T.-H. Kim et al.   CANCER RESEARCH

Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

(2011) Hongting Zheng et al.   DIABETES

Cellular pathophysiology of ischemic acute kidney injury

(2011) Joseph V. Bonventre et al.   JOURNAL OF CLINICAL INVESTIGATION

Nutritional influences on epigenetics and age-related disease

(2011) Lara K. Park et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

The influence of sulforaphane on vascular health and its relevance to nutritional approaches to prevent cardiovascular disease

(2011) Paul C. Evans   EPMA Journal

HIF-1α signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells

(2010) Viktor Malec et al.   FREE RADICAL BIOLOGY AND MEDICINE

HIF-1 Induction Attenuates Nrf2-Dependent IL-8 Expression in Human Endothelial Cells

(2009) Agnieszka Loboda et al.   ANTIOXIDANTS & REDOX SIGNALING

Sulforaphane protects against cisplatin-induced nephrotoxicity

(2009) Carlos Enrique Guerrero-Beltrán et al.   TOXICOLOGY LETTERS

Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme

(2008) Ha-Yong Yoon et al.   BIOCHEMICAL PHARMACOLOGY

An overview of drug-induced acute kidney injury

(2008) Neesh Pannu et al.   CRITICAL CARE MEDICINE

Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney

(2008) C. Rosenberger et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION