Journal
NEPHROLOGY DIALYSIS TRANSPLANTATION
Volume 25, Issue 8, Pages 2397-2399Publisher
OXFORD UNIV PRESS
DOI: 10.1093/ndt/gfq358
Keywords
behavioural abnormalities; children; nephrotic syndrome
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Behaviour and psychosocial adjustment are impaired in children with steroid-sensitive idiopathic nephrotic syndrome (SSNS). Both illness-related variables and family climate play a role. Steroid treatment-both short- and long-term-is an important contributor among other determinants. The exact mechanisms by which steroids lead to behavioural alterations in humans is unclear. Optimizing the benefit/risk ratio of steroid treatment in children with SSNS is a constant goal.
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