Article
Transplantation
Luke Pickup, Charalampos Loutradis, Jonathan P. Law, Julia J. Arnold, Indranil Dasgupta, Pantelis Sarafidis, Jonathan N. Townend, Paul Cockwell, Charles J. Ferro
Summary: This study evaluated the incidence of acute kidney injury using pre-admission and admission creatinine levels and found that even minor increases in creatinine levels were associated with increased mortality. This can help clinicians identify patients at higher risk for adverse outcomes.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Urology & Nephrology
Yeon Joo Lee, Young Seo Park, Seong Jong Park, Won Kyoung Jhang
Summary: This study evaluates the accuracy of different methods for estimating baseline creatinine values in pediatric patients with acute kidney injury. The results suggest that the minimum values of serum creatinine measured within 7 days after hospital admission have the best agreement with creatinine measured within 3 months before admission, indicating their potential use as a baseline when baseline data are unavailable.
KIDNEY RESEARCH AND CLINICAL PRACTICE
(2022)
Article
Medicine, General & Internal
Pier Luigi Palma, Stefano Guarino, Anna Di Sessa, Giulio Rivetti, Annalisa Barlaba, Federica Scaglione, Daniela Capalbo, Alfonso Papparella, Emanuele Miraglia del Giudice, Pierluigi Marzuillo
Summary: Three new equations for estimating basal serum creatinine in hospitalized children have been developed and tested for diagnosing AKI in children with type 1 diabetes mellitus. The ABC-cr and ABC-advanced formulas showed good diagnostic performance for AKI identification.
Review
Urology & Nephrology
Sidar Copur, Abdullah Yildiz, Carlo Basile, Katherine R. Tuttle, Mehmet Kanbay
Summary: SGLT2 inhibitors have shown additional beneficial effects on body weight, serum uric acid levels, blood pressure, and cardiac and renal function. Despite conflicting data, extensive research has demonstrated that SGLT2 inhibitors are safe for the kidney and do not predispose to acute kidney injury (AKI).
JOURNAL OF NEPHROLOGY
(2023)
Article
Gastroenterology & Hepatology
Kavish R. Patidar, Mobasshir A. Naved, Ananth Grama, Mohammad Adibuzzaman, Arzina Aziz Ali, James E. Slaven, Archita P. Desai, Marwan S. Ghabril, Lauren Nephew, Naga Chalasani, Eric S. Orman
Summary: This study investigated hospitalized patients with cirrhosis and acute kidney injury in the US and found that acute kidney disease developed in 1 in 3 patients, which was associated with worse survival and chronic kidney disease.
JOURNAL OF HEPATOLOGY
(2022)
Article
Forestry
Roger Prodon
Summary: The study reveals that recurrent wildfires have an impact on the resilience of a Mediterranean ecosystem, but do not necessarily lead to cumulative degradation. Post-fire avifauna succession is mainly influenced by canopy regeneration and bird species colonization, with recovery of vegetation and bird assemblages taking approximately 15 years.
Review
Urology & Nephrology
Greg Guthrie, Bruce Guthrie, Heather Walker, Matthew T. James, Nicholas M. Selby, Marcello Tonelli, Samira Bell
Summary: This study examined the variation in defining acute kidney injury (AKI) for research using health care data and aimed to achieve consensus. The current methods for defining AKI using routinely collected data are inconsistent and poorly described. Experts could not achieve consensus for many aspects of defining AKI and describing its sequelae. The KDIGO guidelines should be extended to include a standardized definition for AKI when using routinely collected data.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Review
Urology & Nephrology
Deborah Mattinzoli, Paolo Molinari, Gregorio Romero-Gonzalez, Jordi Bover, Elisa Cicero, Francesco Pesce, Matteo Abinti, Costanza Conti, Giuseppe Castellano, Carlo Alfieri
Summary: Cardio-renal syndrome is a well-defined clinical condition that involves interactions between the heart and kidney. Acute kidney injury can lead to chronic cardiovascular events and the progression of kidney disease. The role of bone in this relationship, as well as the impact on long-term outcomes, is an important topic of research.
CLINICAL KIDNEY JOURNAL
(2023)
Article
Transplantation
Rouvick M. Gama, Katherine Clark, Mahua Bhaduri, Amanda Clery, Kelly Wright, Priscilla Smith, Hayley Martin, Royce P. Vincent, Satish Jayawardene, Kate Bramham
Summary: The study found that approximately 1 in 40 pregnancies are affected by Pr-AKI, with common causes being infection, preeclampsia, and hemorrhage. While most women experienced recovery of renal function, about 10% did not recover. The research suggests the need for better understanding of the long-term impacts of Pr-AKI on pregnancy and renal outcomes.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Geriatrics & Gerontology
Libin Xu, Yanhua Wu, Yuanhan Chen, Ruiying Li, Zhiqiang Wang, Zhilian Li, Guoping Liu, Lei Yu, Wei Shi, Xinling Liang
Summary: The study found that the incidence of AKI in older adults showed a U-shaped curve with age, with a significantly higher incidence in those aged 75 and above. However, AKI risk did not increase with age, and the association between AKI and in-hospital death did not increase in an age-dependent manner in older adults.
Article
Biochemistry & Molecular Biology
Sandra M. Sancho-Martinez, Maria Herrero, Miguel Fontecha-Barriuso, Joana Mercado-Hernandez, Francisco J. Lopez-Hernandez
Summary: Urinary injury biomarkers may not necessarily reflect the extent of underlying tissue injury in individual rats, as they show weak correlation and high interindividual variability with tubular damage.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Urology & Nephrology
Erina Ghosh, Larry Eshelman, Stephanie Lanius, Emma Schwager, Kalyan S. Pasupathy, Erin F. Barreto, Kianoush Kashani
Summary: Using a regression-based machine learning model, baseline serum creatinine can be predicted with higher accuracy compared to estimating it through the MDRD equation. The model performed better in terms of error and correlation in both the Mayo Clinic cohort and the MIMIC III cohort, using features such as chronic kidney disease, weight, height, and age.
AMERICAN JOURNAL OF NEPHROLOGY
(2021)
Article
Food Science & Technology
Alexandra Silva, Andre Pereira, Liliana Silva, Angelina Pena
Summary: This study evaluated the inorganic arsenic content of Portuguese rice samples and found that some samples exceeded the maximum residue limit for infant consumption. The estimated arsenic intake for children may exceed the safe threshold, but other sources of arsenic exposure should also be considered.
Article
Chemistry, Multidisciplinary
Alvaro Lobato, Miguel A. Salvado, J. Manuel Recio, Mercedes Taravillo, Valentin G. Baonza
Summary: This study examines the stability boundaries of diatomic bonds, which are found to correlate with topological descriptors of electron density fields. By utilizing chemical databases and quantum-mechanical calculations, a comprehensive analysis of diatomic bonds in the s-p main block of atoms was conducted, with a focus on the impact of substituents in C-C covalent bonds.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Transplantation
Masatoshi Nishimoto, Miho Murashima, Maiko Kokubu, Masaru Matsui, Masahiro Eriguchi, Ken-Ichi Samejima, Yasuhiro Akai, Kazuhiko Tsuruya
Summary: The relationship between kidney function at 3 months after acute kidney injury (AKI) and kidney function prognosis was examined in this study. The study found that AKI patients had a faster decline in estimated glomerular filtration rate (eGFR) after 3 months postoperatively and were associated with incident chronic kidney disease (CKD) and a decline in eGFR >= 30%. The findings suggest the importance of evaluating kidney function beyond 3 months after surgery or using other indicators such as cystatin C values.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)