Article
Medicine, General & Internal
Fei Yang, Meixia Liao, Pusheng Wang, Yongguang Liu
Summary: The study assessed the cost-effectiveness of three renal replacement therapy (RRT) modalities and proposed changes of scheduled policies in RRT composition in Guangzhou city. It found that kidney transplantation (TX) is the most cost-effective RRT modality and suggested increasing the utilization of peritoneal dialysis (PD) and TX in China.
Article
Transplantation
Emily K. Yeung, Kevan R. Polkinghorne, Peter G. Kerr
Summary: This study demonstrates that compared with facility hemodialysis, home hemodialysis patients have a significantly lower risk of death, with comparable rates of transplantation, graft survival, and biochemical control at 6 months post-transplant.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Surgery
Catherine McManus, Aaron Oh, James A. Lee, Chin Hur, Jennifer H. Kuo
Summary: Combining cinacalcet with PTX before kidney transplant is the most cost-effective strategy for treating tertiary hyperparathyroidism in patients with end-stage renal disease.
Article
Surgery
Kristine A. Huynh, Alfred P. Yoon, Anne Seyferth, Kevin C. Chung
Summary: The study demonstrated the positive financial return on investment of implementing office-based ultrasound imaging in hand clinics, with the most critical factors being ultrasound machine cost and procedural volume.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Medicine, General & Internal
Yashika Chugh, Madhumita Premkumar, Gagandeep Singh Grover, Radha K. Dhiman, Yot Teerawattananon, Shankar Prinja
Summary: The study suggests that implementing a one-time universal screening followed by treatment for HCV infected individuals in Punjab, India, is a cost-effective strategy when compared to no screening policy. However, the budget impact of screening all individuals >= 18 years old may be unsustainable. Therefore, the recommendation is to start with screening the age cohort of 40-45 years old with rapid diagnostic tests (RDT) based on both cost-effectiveness and budget impact findings.
Article
Multidisciplinary Sciences
Tingting Zhang, Wenjing Sun, Xing Rong, Jingyi Mu
Summary: This study investigates how the home bias of senior executives affects employee social responsibility in Chinese listed companies. The findings show that home bias can enhance the fulfillment of employee social responsibility. However, the presence of home bias also incurs costs that need to be balanced with potential benefits. Moreover, the impact of senior executives' home bias on employee social responsibility is more significant in firms with less market competition, more governmental subsidies, or state-owned firms.
Article
Immunology
Francesc Lopez, Marti Catala, Clara Prats, Oriol Estrada, Irene Oliva, Nuria Prat, Mar Isnard, Roser Valles, Marc Vilar, Bonaventura Clotet, Josep Maria Argimon, Anna Aran, Jordi Ara
Summary: The study shows that the mass vaccination campaign against COVID is cost-saving, with significant savings coming from the monetization of the reduction in mortality and cases with sequelae from a social perspective. The intervention is widely cost-effective from the health system perspective as well due to the reduction in the use of resources. From an economic perspective, the vaccination campaign has high social returns.
Article
Urology & Nephrology
Dharna Gupta, Gaurav Jyani, Raja Ramachandran, Pankaj Bahuguna, Mohammed Ameel, Bharat Bhushan Dahiya, Harbir Singh Kohli, Shankar Prinja, Vivekanand Jha
Summary: The study showed that initiating kidney replacement therapy with peritoneal dialysis is a cost-saving option in the Indian context compared to haemodialysis, and becomes cost-effective only when the price of peritoneal dialysis consumables is reduced to a certain level.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Economics
Amanda W. Erbe, Dana Kendzia, Ellen Busink, Suzanne Carroll, Eline Aas
Summary: This study aimed to determine the lifetime cost-effectiveness of increasing home hemodialysis as a treatment option for patients experiencing peritoneal dialysis technique failure compared with the current standard of care. The findings suggest that increasing home hemodialysis is a more cost-effective treatment option.
Article
Transplantation
Wisam Bitar, Jaakko Helve, Eero Honkanen, Virpi Rauta, Mikko Haapio, Patrik Finne
Summary: This study compared the survival rate of patients on automated peritoneal dialysis (APD), continuous ambulatory peritoneal dialysis (CAPD), and home hemodialysis (HD). The results showed that the survival rates of patients on home HD and APD were similar, while CAPD patients had a lower survival rate.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Engineering, Environmental
O. O. Ayeleru, F. N. Okonta, F. Ntuli
Summary: The study conducted a cost-benefit analysis of establishing a waste recycling facility, finding an internal rate of return on investment of 42%, internal rate of return on equity of 98%, and a net present value of R 63,420,000 (USD$ 4646225.33). The research indicated the feasibility of the project and the potential to create around 677 jobs.
Article
Oncology
Dirk Mehrens, Marcus Unterrainer, Stefanie Corradini, Maximilian Niyazi, Farkhad Manapov, C. Benedikt Westphalen, Matthias F. Froelich, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Johannes Ruebenthaler, Wolfgang G. Kunz
Summary: The study found that for certain patients with oligometastatic cancers, local treatment with SABR can increase quality-adjusted life years and is a cost-effective treatment strategy in the medium to long term.
FRONTIERS IN ONCOLOGY
(2021)
Article
Substance Abuse
Jose Angelo Divino, Philipp Ehrl, Osvaldo Candido, Marcos Aurelio Pereira Valadao
Summary: Research shows that increasing tobacco taxes in Brazil can effectively reduce smoking and have positive economic impacts on lower-income groups. The benefits include lower medical expenses related to smoking, longer life expectancy, and increased income.
Article
Public, Environmental & Occupational Health
Stacey Orangi, John Ojal, Samuel P. C. Brand, Cameline Orlendo, Angela Kairu, Rabia Aziza, Morris Ogero, Ambrose Agweyu, George M. Warimwe, Sophie Uyoga, Edward Otieno, Lynette Ochola-Oyier, Charles N. Agoti, Kadondi Kasera, Patrick Amoth, Mercy Mwangangi, Rashid Aman, Wangari Ng'ang'a, Ifedayo M. O. Adetifa, J. Anthony G. Scott, Philip Bejon, Matt J. Keeling, Stefan Flasche, D. James Nokes, Edwine Barasa
Summary: This study conducted a cost-effectiveness analysis of COVID-19 vaccine in Kenya. The findings showed that a slow roll-out with 30% coverage was effective in reducing deaths and cost-saving, while increasing coverage to 50% and 70% had limited effectiveness and was not cost-effective. Therefore, vaccinating young adults may no longer be cost-effective in settings where prior exposure has provided partial protection.
Article
Public, Environmental & Occupational Health
Shan Jiang, Yitong Wang, Junwen Zhou, Yawen Jiang, Gordon Guo-En Liu, Jing Wu
Summary: The inclusion of future unrelated medical costs can improve the internal and external consistency of economic evaluation and the comparability of results between different jurisdictions. However, more research is needed to further explore this issue.
Article
Public, Environmental & Occupational Health
Rachael C. Walker, Sally Abel, Suetonia C. Palmer, Curtis Walker, Nayda Heays, David Tipene-Leach
Summary: This paper examines the perceptions and experiences of prejudice and racism among indigenous Maori with kidney disease and their family members and donors. The study reveals that racism exists at institutional, personal, and internal levels, contributing to inequitable outcomes for Maori requiring kidney transplantation in Aotearoa New Zealand.
JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES
(2023)
Article
Economics
Paul Mark Mitchell, Rachael L. Morton, Mickael Hiligsmann, Samantha Husbands, Joanna Coast
Summary: Substantial losses in capability wellbeing were observed during the first year of the COVID-19 pandemic in the UK, Australia, and the Netherlands. Future research is needed to understand the specific impact of different COVID-19 restrictions on individuals' capabilities.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Urology & Nephrology
Chandana Guha, Anita van Zwieten, Rabia Khalid, Siah Kim, Amanda Walker, Anna Francis, Madeleine Didsbury, Armando Teixeira-Pinto, Belinda Barton, Chanel Prestidge, Emily Lancsar, Fiona Mackie, Joseph Kwon, Kirsten Howard, Kylie-Ann Mallitt, Martin Howell, Allison Jaure, Alison Hayes, Rakhee Raghunandan, Stavros Petrou, Suncica Lah, Steven McTaggart, Jonathan C. Craig, Germaine Wong
Summary: This multi-center longitudinal cohort study aimed to assess the trajectories of health-related quality of life (HRQoL) in children with chronic kidney disease (CKD) over time. The results showed that the HRQoL scores differed between children with different CKD stages, and the transition from dialysis to transplantation was significantly associated with the improvement in HRQoL. Children with CKD stage 1-5 and transplant recipients at baseline had stable HRQoL over time.
KIDNEY INTERNATIONAL
(2023)
Article
Pediatrics
Chandana Guha, Rabia Khalid, Anita van Zwieten, Anna Francis, Carmel M. Hawley, Allison Jaure, Armando Teixeira-Pinto, Alistair R. Mallard, Amelie Bernier-Jean, David W. Johnson, Deirdre Hahn, Donna Reidlinger, Elaine M. Pascoe, Elizabeth G. Ryan, Fiona Mackie, Hugh J. McCarthy, Jonathan C. Craig, Julie Varghese, Charani Kiriwandeniya, Kirsten Howard, Nicholas G. Larkins, Luke Macauley, Amanda Walker, Martin Howell, Michelle Irving, Patrina H. Y. Caldwell, Reginald Woodleigh, Shilpanjali Jesudason, Simon A. Carter, Sean E. Kennedy, Stephen Alexander, Steven McTaggart, Germaine Wong
Summary: This study aims to evaluate the effectiveness of a patient navigator program in children with chronic kidney disease. A total of 162 patients were enrolled and randomized into immediate intervention and waitlisted groups. The results of the study will be completed by October 2022.
PEDIATRIC NEPHROLOGY
(2023)
Correction
Economics
Karan K. Shah, Melina Willson, Blaise Agresta, Rachael L. Morton
PHARMACOECONOMICS-OPEN
(2023)
Article
Rehabilitation
Marina B. Pinheiro, Leanne Hassett, Catherine Sherrington, Alison Hayes, Maayken van den Berg, Richard Lindley, Maria Crotty, Sakina Chagpar, Daniel Treacy, Heather Weber, Nicola Fairhall, Siobhan Wong, Annie McCluskey, Leanne Togher, Katharine Scrivener, Kirsten Howard
Summary: This study evaluated the cost-effectiveness of adding a tailored digitally enabled exercise intervention to usual care in improving mobility, showing that the intervention saved costs and was more effective for mobility and quality-adjusted life years compared to usual care. Decision makers willing to pay AU$50,000 per meaningful improvement in mobility or quality-adjusted life year gained had a high probability of the intervention being cost-effective.
CLINICAL REHABILITATION
(2023)
Letter
Dermatology
Yuan Ni, Caroline G. Watts, Richard A. Scolyer, Christine Madronio, Bruce K. Armstrong, Rachael L. Morton, Scott W. Menzies, Graham J. Mann, John F. Thompson, Serigne N. Lo, Anne E. Cust
Summary: This cross-sectional survey identified risk factors for developing a second primary melanoma. Patients with melanoma who had characteristics such as male sex, older age, high naevus count, or melanoma on the trunk or upper limbs had a substantially higher risk of subsequent melanoma and should therefore be more intensively monitored.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Urology & Nephrology
Mark R. Marshall, Gerald P. Waters, Christian Verger
Summary: In this study, a simple method for estimating the peritonitis rate in peritoneal dialysis (PD) was validated and found to have good agreement with gold-standard measurements in two large dialysis registries. However, the International Society of Peritoneal Dialysis (ISPD) hesitated to recommend its adoption due to concerns about potential inaccuracies. Further analysis of the data sets confirmed the accuracy of the estimating equation and showed that its use would not compromise clinical decision-making for most patients.
PERITONEAL DIALYSIS INTERNATIONAL
(2023)
Article
Medicine, Research & Experimental
Mabel K. Yan, Anne E. Cust, H. Peter Soyer, Monika Janda, Katja Loewe, Gabrielle Byars, Paul Fishburn, Paul White, Rashidul Alam Mahumud, Robyn P. M. Saw, Alan Herschtal, Pablo Fernandez-Penas, Pascale Guitera, Rachael L. Morton, John Kelly, Rory Wolfe, Victoria J. Mar
Summary: This study aims to evaluate the clinical impact and cost-effectiveness of using Melanoma surveillance photography (MSP) for individuals at ultra-high or high risk of melanoma. The study is a randomized controlled trial (RCT) conducted over 3 years, with 580 participants from three Australian states. The primary outcome measure is the number of unnecessary biopsies, and secondary outcomes include health economic outcomes, quality of life, and patient acceptability. The results of this study will contribute to policy decision-making and the clinical application of MSP.
Review
Economics
Joseph Kwon, Sarah Smith, Rakhee Raghunandan, Martin Howell, Elisabeth Huynh, Sungwook Kim, Thomas Bentley, Nia Roberts, Emily Lancsar, Kirsten Howard, Germaine Wong, Jonathan Craig, Stavros Petrou
Summary: This study conducted a systematic review of psychometric evidence for generic childhood MAUIs and provides comprehensive evidence on their performance. It assists in selecting instruments based on scientific rigor and identifies gaps and methodological issues for future research.
APPLIED HEALTH ECONOMICS AND HEALTH POLICY
(2023)
Review
Pediatrics
Zoe Wei, Yasmin Gilbert, Arabhi Thananjeyan, James Cope, Rachael L. Morton, Annie Li, Cecile T. Pham, Meredith Ward, Ju Lee Oei
Summary: This systematic review evaluated the quality and availability of clinical practice guidelines for neonatal abstinence syndrome. The findings suggest that the majority of guidelines are of insufficient quality, highlighting the need for more high-quality research to guide clinical practice and improve care.
Article
Health Care Sciences & Services
Ann Livingstone, Kirsten Howard, Alexander M. Menzies, Georgina V. Long, Martin R. Stockler, Rachael L. Morton
Summary: This study aimed to quantify adult preferences for adjuvant immunotherapy for resected melanoma and the influence of varying levels of key attributes and baseline characteristics. The study found that 70% of respondents chose adjuvant immunotherapy over no adjuvant immunotherapy, preferring treatment that improved efficacy and safety. The importance of this study is rated 8 out of 10.
PATIENT-PATIENT CENTERED OUTCOMES RESEARCH
(2023)
Article
Health Care Sciences & Services
Abby Haynes, Kirsten Howard, Liam Johnson, Gavin Williams, Kelly Clanchy, Sean Tweedy, Adam Scheinberg, Sakina Chagpar, Belinda Wang, Gabrielle Vassallo, Rhys Ashpole, Catherine Sherrington, Leanne Hassett
Summary: This study successfully developed a discrete choice experiment survey tool through discussions and interviews with patients with moderate-to-severe traumatic brain injury. The tool aimed to understand the preferences for physical activity among these patients and improve the World Health Organization guidelines for physical activity in traumatic brain injury. The formative co-development process significantly improved the relevance and comprehensibility of the survey tool.
PATIENT-PATIENT CENTERED OUTCOMES RESEARCH
(2023)
Review
Economics
Tessa Peasgood, Martin Howell, Rakhee Raghunandan, Amber Salisbury, Marcus Sellars, Gang Chen, Joanna Coast, Jonathan C. Craig, Nancy J. Devlin, Kirsten Howard, Emily Lancsar, Stavros Petrou, Julie Ratcliffe, Rosalie Viney, Germaine Wong, Richard Norman, Cam Donaldson
Summary: This study aimed to synthesize knowledge on the social value of child and adult health and found that the majority of studies supported prioritizing children. However, not all studies were consistent with this view, and there are research gaps in understanding the value of health gains for very young children and the motivations behind the public's views.