☆ 4.3 Article

ACUTE INTERSTITIAL NEPHRITIS SECONDARY TO DEFERASIROX CAUSING ACUTE RENAL INJURY NEEDING SHORT-TERM DIALYSIS

NEPHROLOGY (2010)

Journal

NEPHROLOGY

Volume 15, Issue 3, Pages 377-377

Publisher

WILEY-BLACKWELL PUBLISHING, INC

DOI: 10.1111/j.1440-1797.2009.01183.x

Keywords

-

Categories

Urology & Nephrology

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Authors

I am an author on this paper

Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.3

Not enough ratings

Secondary Ratings

Novelty

-

Significance

-

Scientific rigor

-

Rate this paper

Recommended

Article Urology & Nephrology

Recurrent acute interstitial nephritis: what lies beneath

Fernando Caravaca-Fontan, Amir Shabaka, Beatriz Sanchez-Alamo, Alberto de Lorenzo, Martha Diaz, Miquel Blasco, Eva Rodriguez, Milagros Sierra-Carpio, Tamara Malek Marin, Andres Urrestarazu, Clara Corona Cases, Manuel Praga, Gema Fernandez-Juarez

Summary: Acute interstitial nephritis (AIN) is an emerging cause of acute kidney disease, with recurrent AIN (RAIN) posing a major challenge. In some cases, unclear reasons lead to the occurrence of RAIN, prompting clinicians to be cautious. Treatment strategies for the disease include corticosteroids and other medications.

CLINICAL KIDNEY JOURNAL (2021)

Add to Collection

Article Urology & Nephrology

The spectrum of biopsy-proven kidney diseases, causes, and renal outcomes in acute kidney injury patients

Zulihumaer Abuduwupuer, Qunjuan Lei, Shaoshan Liang, Feng Xu, Dandan Liang, Xue Yang, Xumeng Liu, Caihong Zeng

Summary: This study analyzed the pathological spectrum, causes, and renal outcomes of biopsied AKI patients. Results showed that most biopsied AKI patients had coexisting glomerular disease, while a small number of patients had tubular/tubulointerstitial nephropathy alone. Patients with glomerular disease mainly presented as stage 1 AKI, while tubular/tubulointerstitial nephropathy patients mainly presented as stage 3 AKI. There were differences in renal function recovery between different types of patients.

NEPHRON (2023)

Add to Collection

Article Urology & Nephrology

Prognosis of severe drug-induced acute interstitial nephritis requiring renal replacement therapy

Li Huang, Shaoshan Liang, Jianhua Dong, Wenjing Fan, Caihong Zeng, Ti Zhang, Shuiqin Cheng, Yongchun Ge

Summary: This study evaluated the prognosis of patients with severe DAIN requiring RRT and identified risk factors for progression to CKD. Higher peak cystatin C concentration and longer interval to treatment with corticosteroids were associated with worse renal outcomes in these patients.

RENAL FAILURE (2021)

Add to Collection

Article Infectious Diseases

Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis Recto: Cefiderocol causing acute interstitial nephritis

Kimberly Cipko, Alice Kizny Gordon, Suman Adhikari, Pamela Konecny

Summary: This article reports a successful salvage treatment of XDRAB and Pseudomonas aeruginosa-infected retained spinal hardware with cefiderocol, despite the development of reversible acute interstitial nephritis after 32 days of treatment.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Renal Fibrosis in Lupus Nephritis

Savino Sciascia, Martina Cozzi, Alice Barinotti, Massimo Radin, Irene Cecchi, Roberta Fenoglio, Daniele Mancardi, Georgia Wilson Jones, Daniela Rossi, Dario Roccatello

Summary: Fibrosis is a pathological process that can affect the kidney, leading to persistent inflammation or long-term injury. Recently, there has been increasing attention on interstitial fibrosis and tubular atrophy as markers of injury severity, predictors of treatment response, and prognostic factors for renal outcome in lupus nephritis (LN). This review explores the mechanisms of fibrogenesis in LN and the importance of the chronicity index in predicting treatment response and renal prognosis. Understanding the cellular and molecular pathways involved in fibrosis in LN could help identify individuals at higher risk of chronic kidney disease and develop new therapeutic strategies for lupus patients.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Add to Collection

Article Cell Biology

Spatial proteomics landscape and immune signature analysis of renal sample of lupus nephritis based on laser-captured microsection

Fengping Zheng, Donge Tang, Shanshan Li, Zhifeng Luo, Yueqi Song, Yinxin Huang, Qing Gan, Hanyong Liu, Xinzhou Zhang, Dongzhou Liu, Qingwen Wang, Zuying Xiong, Yong Dai

Summary: This study used laser capture microdissection (LCM) to analyze the kidney in lupus nephritis (LN). The glomerulus and interstitial were identified as major sites of immune disturbance and regulation. Additionally, several hub genes correlated with immune cell infiltration were identified. ALB, CTSB, LCN2, A2M, CDC42, VIM, LTF, and CD14 were suggested as candidate biomarkers based on their correlation with clinical indexes.

INFLAMMATION RESEARCH (2023)

Add to Collection

Article Rheumatology

Renal involvement in Sjogren's syndrome: predictors and impact on patient outcomes

Rudrarpan Chatterjee, Anu Balakrishnan, Rajat Kharbanda, Upendra Rathore, Latika Gupta, Durga P. Misra, Vikas Agarwal, Amita Aggarwal, Able Lawrence

Summary: This study investigated renal disease in patients with primary Sjogren's Syndrome (pSS) in India, revealing tubulointerstitial nephritis (TIN) and glomerulonephritis (GN) as the two common types of renal disease in pSS. The study highlighted the impact of renal disease on patient outcomes, including death and chronic kidney disease (CKD).

RHEUMATOLOGY INTERNATIONAL (2023)

Add to Collection

Article Virology

Caprine Arthritis Encephalitis Virus Is Associated with Renal Lesions

Brian G. Murphy, Diego Castillo, Asli Mete, Helena Vogel, Dayna Goldsmith, Marietta Barro, Omar Gonzales-Viera

Summary: The text discusses chronic inflammatory syndromes caused by Caprine arthritis encephalitis virus (CAEV) in goats, focusing on joint synovium, central nervous system tissues, pulmonary interstitium, and mammary gland. It also reports cases of CAEV-associated renal lesions in six goats, with one animal presenting with CAEV antigen-associated thrombotic arteritis.

VIRUSES-BASEL (2021)

Add to Collection

Article Transplantation

Urine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritis

Dennis G. Moledina, F. Perry Wilson, Lidiya Kukova, Wassim Obeid, Randy Luciano, Michael Kuperman, Gilbert W. Moeckel, Michael Kashgarian, Mark A. Perazella, Lloyd G. Cantley, Chirag R. Parikh

Summary: In patients with acute interstitial nephritis (AIN), urine interleukin (IL)-9 levels can predict kidney function, while corticosteroid use is associated with glomerular filtration rate at 6 months post-diagnosis, especially in patients with high urine IL-9 levels.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Renal disease in sarcoidosis patients in a German multicentric retrospective cohort study

Raoul Bergner, Stefan M. Weiner, Gabriele Kehl, Kirsten de Groot, Sandra Tielke, Thomas Asendorf, Peter Korsten

Summary: Sarcoidosis is a systemic granulomatous disease that can affect every organ system. Renal involvement, although rare, is present in approximately 27.5% of patients with sarcoidosis. The prevalence of renal sarcoidosis in this study is higher than previously reported, indicating a significant disease burden.

RESPIRATORY MEDICINE (2023)

Add to Collection

Article Urology & Nephrology

The extent of tubulointerstitial inflammation is an independent predictor of renal survival in lupus nephritis

Manuel Ferreira Gomes, Claudia Mardones, Marc Xipell, Miquel Blasco, Manel Sole, Gerard Espinosa, Adriana Garcia-Herrera, Ricard Cervera, Luis F. Quintana

Summary: A retrospective study of 166 patients with biopsy-proven LN in a Spanish referral center showed that the prevalence of tubulointerstitial lesions was 69.3%. Patients with features of tubulointerstitial inflammation had shorter renal survival. The extent of tubulointerstitial inflammation emerged as an independent predictor of renal survival after adjusting for other factors.

JOURNAL OF NEPHROLOGY (2021)

Add to Collection

Article Urology & Nephrology

Renal thrombotic microangiopathy associated to worse renal prognosis in Lupus Nephritis

Fernando Louzada Strufaldi, Precil Diego Miranda de Menezes Menezes Neves, Cristiane Bitencourt Dias, Luis Yu, Viktoria Woronik, Livia Barreira Cavalcante, Denise Maria Avancini Costa Malheiros, Lecticia Barbosa Jorge

Summary: This study evaluated the clinical and pathological aspects of patients with lupus and rTMA in kidney biopsy, finding that patients with rTMA had poorer kidney function and prognosis. The presence of rTMA was associated with significantly lower eGFR values and a higher risk of reaching the composite endpoint of eGFR < 15 mL/min/1.73m2, death, or dialysis. Additionally, rTMA patients showed higher percentages of anemia, thrombocytopenia, and low haptoglobin levels, and a higher histological activity and chronicity score, highlighting the importance of renal biopsy for prognosis assessment.

JOURNAL OF NEPHROLOGY (2021)

Add to Collection

Article Oncology

Infliximab for the treatment of patients with checkpoint inhibitor-associated acute tubular interstitial nephritis

Jamie S. Lin, Omar Mamlouk, Umut Selamet, Amanda Tchakarov, William F. Glass, Rahul A. Sheth, Rachel M. Layman, Ramona Dadu, Noha Abdelwahab, Maen Abdelrahim, Adi Diab, Cassian Yee, Ala Abudayyeh

Summary: Infliximab may be a treatment option for achieving durable and complete renal recovery in patients with CPI-ATIN, representing a potential steroid-sparing strategy in challenging cases. Rigorous clinical studies are needed to evaluate the risk-benefit analysis for infliximab usage in CPI-ATIN patients.

ONCOIMMUNOLOGY (2021)

Add to Collection

Article Oncology

Alectinib - induced acute renal failure

Elena Prado-Mel, Pablo Ciudad-Gutierrez, Almudena Sanchez-Martin, Laila Abdel-Kader Martin

Summary: This article reports a case of acute interstitial nephritis and acute tubular necrosis in a patient after treatment with Alectinib. The diagnosis was confirmed by renal biopsy. After aggressive treatment, the patient's renal function recovered.

JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2023)

Add to Collection

Article Transplantation

Development and external validation of a diagnostic model for biopsy-proven acute interstitial nephritis using electronic health record data

Dennis G. Moledina, Michael T. Eadon, Frida Calderon, Yu Yamamoto, Melissa Shaw, Mark A. Perazella, Michael Simonov, Randy Luciano, Tae-Hwi Schwantes-An, Gilbert Moeckel, Michael Kashgarian, Michael Kuperman, Wassim Obeid, Lloyd G. Cantley, Chirag R. Parikh, F. Perry Wilson

Summary: This study developed and validated a diagnostic model for identifying patients at risk of AIN. The model utilized multiple variables from the electronic health record and was validated in different cohorts. The results showed improved performance of the model after the addition of urine biomarkers.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2022)

Add to Collection

Article Urology & Nephrology

Comparison of cause of death between Australian and New Zealand Dialysis and Transplant Registry and the Australian National Death Index

Matthew P. Sypek, Kathryn B. Dansie, Phil Clayton, Angela C. Webster, Stephen Mcdonald

NEPHROLOGY (2019)

Add to Collection

Article Surgery

Quantifying lead time bias when estimating patient survival in preemptive living kidney donor transplantation

Georgina L. Irish, Steve Chadban, Stephen McDonald, Philip A. Clayton

AMERICAN JOURNAL OF TRANSPLANTATION (2019)

Add to Collection

Article Surgery

Insights into the labeling effect of Kidney Donor Performance Index reporting: The Australian experience

Matthew P. Sypek, Peter Hughes, Rhonda Holdsworth, John Kanellis, Stephen McDonald, Philip D. Clayton

AMERICAN JOURNAL OF TRANSPLANTATION (2020)

Add to Collection

Article Surgery

Development and implementation of an enhanced recovery after surgery protocol for renal transplantation

Brendan H. Dias, Abdul Ahad Muhammad Rana, Santosh A. Olakkengil, Christine H. Russell, Patrick T. H. Coates, Philip A. Clayton, Shantanu Bhattacharjya

ANZ JOURNAL OF SURGERY (2019)

Add to Collection

Article Pediatrics

Human leukocyte antigen eplet mismatches and long-term clinical outcomes in pediatric renal transplantation: A pragmatic, registry-based study

Matthew P. Sypek, Steve Hiho, Linda Cantwell, Phil Clayton, Peter Hughes, Amelia K. Le Page, Joshua Kausman

PEDIATRIC TRANSPLANTATION (2020)

Add to Collection

Article Surgery

Socio-economic disparity, access to care and patient-relevant outcomes after kidney allograft failure

Yun Hui Sheryl Wong, Germaine Wong, David W. Johnson, Stephen McDonald, Philip Clayton, Neil Boudville, Andrea K. Viecelli, Charmaine Lok, Helen Pilmore, Carmel Hawley, Matthew A. Roberts, Rachael Walker, Esther Ooi, Kevan R. Polkinghorne, Wai H. Lim

Summary: This study identified that patients with lower socio-economic status were less likely to receive repeat transplants and more likely to die during dialysis post-allograft failure.

TRANSPLANT INTERNATIONAL (2021)

Add to Collection

Article Surgery

Healthcare professional and community preferences in deceased donor kidney allocation: A best-worst scaling survey

Matthew P. Sypek, Martin Howell, Kirsten Howard, Germaine Wong, Emily Duncanson, Philip D. Clayton, Peter Hughes, Stephen McDonald

Summary: The study found that community members prioritize equity in kidney allocation, while healthcare professionals focus on maximizing utility. There are discordant views between community members and healthcare professionals, which should be taken into consideration in the design, evaluation, and implementation of deceased donor kidney allocation protocols.

AMERICAN JOURNAL OF TRANSPLANTATION (2022)

Add to Collection

Article Urology & Nephrology

Determinants of Perinatal Outcomes in Dialyzed and Transplanted Women in Australia

Erandi Hewawasam, Christopher E. Davies, Zhuoyang Li, Philip Clayton, Elizabeth Sullivan, Stephen P. McDonald, Shilpanjali Jesudason

Summary: Pregnancies of women receiving chronic kidney replacement therapy (KRT) have higher risks of adverse perinatal outcomes, including preterm birth and low birthweight. Pregnancy-induced hypertension is not the main determinant of perinatal morbidity.

KIDNEY INTERNATIONAL REPORTS (2022)

Add to Collection

Biographical-Item Medicine, General & Internal

Richard John Cook OBITUARY

Philip Clayton, Simon Lennane

BMJ-BRITISH MEDICAL JOURNAL (2022)

Add to Collection

Article Urology & Nephrology

Incidence, Risk Factors, and Outcomes of Kidney Transplant Recipients With BK Polyomavirus-Associated Nephropathy

Ryan Gately, Elasma Milanzi, Wai Lim, Armando Teixeira-Pinto, Phil Clayton, Nicole Isbel, David W. Johnson, Carmel Hawley, Scott Campbell, Germaine Wong

Summary: BK polyomavirus-associated nephropathy (BKPyVAN) is associated with an increased risk of graft dysfunction and loss in kidney transplant recipients. This cohort study in Australia and New Zealand found that BKPyVAN occurred in 3% of recipients and was linked to higher rates of graft loss, rejection, and death. Changes in immunosuppression, such as reducing tacrolimus and mycophenolate doses, were commonly made after BKPyVAN. Several factors, including gender, age, blood group, donor characteristics, transplantation era, immunosuppression use, and transplant center volume, were associated with the development of BKPyVAN. The study also found that BKPyVAN increased the risk of graft loss but not mortality. It highlights the need for interventional trials to evaluate strategies for reducing immunosuppression and minimizing adverse outcomes associated with BKPyVAN.

KIDNEY INTERNATIONAL REPORTS (2023)

Add to Collection

Article Ethics

Respecting living kidney donor autonomy: an argument for liberalising living kidney donor acceptance criteria

Alison C. Weightman, Simon Coghlan, Philip A. Clayton

Summary: The refusal of doctors to accept donations from living kidney donors with certain comorbidities is unjustified according to this paper. The paper argues for greater acceptance of such donations to address the ongoing shortage of kidney transplants.

MONASH BIOETHICS REVIEW (2023)

Add to Collection

Article Urology & Nephrology

Preeclampsia after Kidney Transplantation Rates and Association with Graft Survival and Function

Joe Lu, Erandi Hewawasam, Christopher E. Davies, Philip A. Clayton, Stephen P. McDonald, Shilpanjali Jesudason

Summary: This study aimed to determine the rates of preeclampsia in women with kidney transplants and its association with graft survival and function. The results showed that while preeclampsia is common in women with transplanted kidneys, it is not associated with worse graft survival or function.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2023)

Add to Collection

Article Urology & Nephrology

Center-Effect of Incident Hemodialysis Vascular Access Use: Analysis of a Bi-national Registry

Samantha Ng, Elaine M. Pascoe, David W. Johnson, Carmel M. Hawley, Kevan R. Polkinghorne, Stephen McDonald, Philip A. Clayton, Kannaiyan S. Rabindranath, Matthew A. Roberts, Ashley B. Irish, Andrea K. Viecelli

Summary: This study identified several patient and center factors associated with incident HD access use, yet these factors did not fully explain the substantial variability in arteriovenous access use across centers. Adjustment for center-level characteristics resulted in a 25% reduction in observed intercenter variability of arteriovenous access use at HD initiation compared with the model adjusted for only patient-level characteristics.

KIDNEY360 (2021)

Add to Collection

Meeting Abstract Urology & Nephrology

A NEGATIVE TACHYCARDIC-INDUCED CARDIAC STRESS TEST PREDICTS AGAINST 30 DAY PERI-OPERATIVE CARDIOVASCULAR MORTALITY POST RENAL TRANSPLANTATION

T. Salehi, N. J. Montarello, A. P. Bate, P. A. Clayton, M. I. Worthley, P. T. Coates

NEPHROLOGY (2020)

Add to Collection

Article Philosophy

PROSPECTS FOR PANENTHEISM AS RESEARCH PROGRAM

Philip Clayton

EUROPEAN JOURNAL FOR PHILOSOPHY OF RELIGION (2019)

Add to Collection

No Data Available

© Peeref 2019-2024. All rights reserved.