Impact of aggregate formation on the viscosity of protein solutions

A multiscale view of therapeutic protein aggregation: A colloid science perspective

(2015) Lucrèce Nicoud et al.   Biotechnology Journal

A multiscale view of therapeutic protein aggregation: A colloid science perspective

(2015) Lucrèce Nicoud et al.   Biotechnology Journal

Protein aggregation, particle formation, characterization & rheology

(2014) Samiul Amin et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Kinetic Analysis of the Multistep Aggregation Mechanism of Monoclonal Antibodies

(2014) Lucrèce Nicoud et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Do Clustering Monoclonal Antibody Solutions Really Have a Concentration Dependence of Viscosity?

(2013) Jai A. Pathak et al.   BIOPHYSICAL JOURNAL

Monoclonal Antibody Self-Association, Cluster Formation, and Rheology at High Concentrations

(2013) Wayne G. Lilyestrom et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Both protein adsorption and aggregation contribute to shear yielding and viscosity increase in protein solutions

(2013) Maria Monica Castellanos et al.   Soft Matter

Shear rheology of hard-sphere, dispersed, and aggregated suspensions, and filler-matrix composites

(2012) Diego B. Genovese   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Weak Interactions Govern the Viscosity of Concentrated Antibody Solutions: High-Throughput Analysis Using the Diffusion Interaction Parameter

(2012) Brian D. Connolly et al.   BIOPHYSICAL JOURNAL

Population Balance Modeling of Antibodies Aggregation Kinetics

(2012) Paolo Arosio et al.   JOURNAL OF PHYSICAL CHEMISTRY B

What's fueling the biotech engine—2011 to 2012

(2012) Saurabh Aggarwal   NATURE BIOTECHNOLOGY

Viscosity measurements of antibody solutions by photon correlation spectroscopy: an indirect approach – limitations and applicability for high-concentration liquid protein solutions

(2012) Michael Wagner et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Aggregates in monoclonal antibody manufacturing processes

(2011) María Vázquez-Rey et al.   BIOTECHNOLOGY AND BIOENGINEERING

Thermally induced inactivation and aggregation of urease: Experiments and population balance modelling

(2011) Peter Grancic et al.   CHEMICAL ENGINEERING SCIENCE

Predicting solution aggregation rates for therapeutic proteins: Approaches and challenges

(2011) Christopher J. Roberts et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Viscosity Behavior of High-Concentration Protein Mixtures

(2011) William J. Galush et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effect of Sugar Molecules on the Viscosity of High Concentration Monoclonal Antibody Solutions

(2011) Feng He et al.   PHARMACEUTICAL RESEARCH

Diffusion and Sedimentation Interaction Parameters for Measuring the Second Virial Coefficient and Their Utility as Predictors of Protein Aggregation

(2010) Atul Saluja et al.   BIOPHYSICAL JOURNAL

High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions

(2009) Feng He et al.   ANALYTICAL BIOCHEMISTRY

The critical role of mobile phase composition in size exclusion chromatography of protein pharmaceuticals

(2009) Tsutomu Arakawa et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Generation and Geometrical Analysis of Dense Clusters with Variable Fractal Dimension

(2009) Lyonel Ehrl et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Long- and Short-Range Electrostatic Interactions Affect the Rheology of Highly Concentrated Antibody Solutions

(2009) Ravi Chari et al.   PHARMACEUTICAL RESEARCH

Average protein density is a molecular-weight-dependent function

(2004) Hannes Fischer et al.   PROTEIN SCIENCE