XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining
Authors
Keywords
-
Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Nature America, Inc
Online
2018-09-29
DOI
10.1038/s41594-018-0133-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN
- (2017) Nausica Arnoult et al. NATURE
- Non-homologous DNA end joining and alternative pathways to double-strand break repair
- (2017) Howard H. Y. Chang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination
- (2016) H. IJspeert et al. BLOOD
- An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex
- (2016) Michal Hammel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Two-Stage Synapsis of DNA Ends during Non-homologous End Joining
- (2016) Thomas G.W. Graham et al. MOLECULAR CELL
- Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA
- (2016) Ineke Brouwer et al. NATURE
- PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF
- (2016) Satish K. Tadi et al. Cell Reports
- Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair
- (2015) Dylan A. Reid et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
- (2015) T. Ochi et al. SCIENCE
- DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1/2 that promotes efficient DNA repair
- (2015) Brittany J Belin et al. eLife
- One ring to bring them all—The role of Ku in mammalian non-homologous end joining
- (2014) Gabrielle J. Grundy et al. DNA REPAIR
- Identification and Functional Characterization of a Ku-binding Motif in Aprataxin Polynucleotide Kinase/Phosphatase-like Factor (APLF)
- (2013) Purnata Shirodkar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
- (2013) Sébastien Britton et al. JOURNAL OF CELL BIOLOGY
- A noncatalytic function of the ligation complex during nonhomologous end joining
- (2013) Jessica Cottarel et al. JOURNAL OF CELL BIOLOGY
- Video-rate nanoscopy using sCMOS camera–specific single-molecule localization algorithms
- (2013) Fang Huang et al. NATURE METHODS
- Protein analysis by time-resolved measurements with an electro-switchable DNA chip
- (2013) Andreas Langer et al. Nature Communications
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Exploiting structure similarity in refinement: automated NCS and target-structure restraints inBUSTER
- (2012) Oliver S. Smart et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Non-homologous end-joining partners in a helical dance: structural studies of XLF–XRCC4 interactions
- (2012) Qian Wu et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Advances in X-ray scattering: from solution SAXS to achievements with coherent beams
- (2012) Javier Pérez et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- APLF promotes the assembly and activity of non-homologous end joining protein complexes
- (2012) Gabrielle J Grundy et al. EMBO JOURNAL
- New developments in theATSASprogram package for small-angle scattering data analysis
- (2012) Maxim V. Petoukhov et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- A human XRCC4–XLF complex bridges DNA
- (2012) Sara N. Andres et al. NUCLEIC ACIDS RESEARCH
- Correlation Functions Quantify Super-Resolution Images and Estimate Apparent Clustering Due to Over-Counting
- (2012) Sarah L. Veatch et al. PLoS One
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Live cell imaging of XLF and XRCC4 reveals a novel view of protein assembly in the non-homologous end-joining pathway
- (2011) Ken-ichi Yano et al. CELL CYCLE
- Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF
- (2011) Ken-ichi Yano et al. FEBS LETTERS
- XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair
- (2011) Michal Hammel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Correct End Use during End Joining of Multiple Chromosomal Double Strand Breaks Is Influenced by Repair Protein RAD50, DNA-dependent Protein Kinase DNA-PKcs, and Transcription Context
- (2011) Amanda Gunn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
- (2011) Qiao Cheng et al. NUCLEIC ACIDS RESEARCH
- Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining
- (2011) V. Ropars et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MultiBac: expanding the research toolbox for multiprotein complexes
- (2011) Christoph Bieniossek et al. TRENDS IN BIOCHEMICAL SCIENCES
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
- (2010) Michael R. Lieber Annual Review of Biochemistry
- Small-angle X-ray and neutron scattering as a tool for structural systems biology
- (2010) Dmitri I. Svergun BIOLOGICAL CHEMISTRY
- Roles of Werner syndrome protein in protection of genome integrity
- (2010) Marie L. Rossi et al. DNA REPAIR
- Delineation of the Xrcc4-interacting Region in the Globular Head Domain of Cernunnos/XLF
- (2010) Laurent Malivert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- XLF Regulates Filament Architecture of the XRCC4·Ligase IV Complex
- (2010) Michal Hammel et al. STRUCTURE
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structural and Functional Interaction between the Human DNA Repair Proteins DNA Ligase IV and XRCC4
- (2009) P.-Y. Wu et al. MOLECULAR AND CELLULAR BIOLOGY
- Limiting the Persistence of a Chromosome Break Diminishes Its Mutagenic Potential
- (2009) Nicole Bennardo et al. PLoS Genetics
- APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation
- (2008) Chloe J. Macrae et al. DNA REPAIR
- The C-Terminal Domain of Cernunnos/XLF Is Dispensable for DNA Repair In Vivo
- (2008) L. Malivert et al. MOLECULAR AND CELLULAR BIOLOGY
- APLF (C2orf13) Is a Novel Component of Poly(ADP-Ribose) Signaling in Mammalian Cells
- (2008) S. L. Rulten et al. MOLECULAR AND CELLULAR BIOLOGY
- Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
- (2008) Ivan Ahel et al. NATURE
- Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair
- (2008) Nicole Bennardo et al. PLoS Genetics
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started