Structural basis of the filamin A actin-binding domain interaction with F-actin

Thoracic aortic aneurysm in patients with loss of function Filamin A mutations: Clinical characterization, genetics, and recommendations

(2018) Ming Hui Chen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The actin filament twist changes abruptly at boundaries between bare and cofilin-decorated segments

(2018) Andrew Huehn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing

(2018) Ahmet Mentes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Actin Cytoskeleton and Actin-Based Motility

(2018) Tatyana Svitkina   Cold Spring Harbor Perspectives in Biology

Differential regulation of two FLNA transcripts explains some of the phenotypic heterogeneity in the loss-of-function filaminopathies

(2017) Zandra A Jenkins et al.   HUMAN MUTATION

Helical reconstruction in RELION

(2017) Shaoda He et al.   JOURNAL OF STRUCTURAL BIOLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation

(2017) Adam W. Avery et al.   Nature Communications

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Actin and Actin-Binding Proteins

(2016) Thomas D. Pollard   Cold Spring Harbor Perspectives in Biology

Automatic estimation and correction of anisotropic magnification distortion in electron microscopes

(2015) Timothy Grant et al.   JOURNAL OF STRUCTURAL BIOLOGY

ChEBI in 2016: Improved services and an expanding collection of metabolites

(2015) Janna Hastings et al.   NUCLEIC ACIDS RESEARCH

Structural Insights into Ca 2+ -Calmodulin Regulation of Plectin 1a-Integrin β4 Interaction in Hemidesmosomes

(2015) Jae-Geun Song et al.   STRUCTURE

Exome sequencing identifies a mutation in the ACTN2 gene in a family with idiopathic ventricular fibrillation, left ventricular noncompaction, and sudden death

(2014) Richard D Bagnall et al.   BMC Medical Genetics

Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy

(2014) Rafael Valdés-Mas et al.   Nature Communications

ACTN1 Mutations Cause Congenital Macrothrombocytopenia

(2013) Shinji Kunishima et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ASB2α, an E3 Ubiquitin Ligase Specificity Subunit, Regulates Cell Spreading and Triggers Proteasomal Degradation of Filamins by Targeting the Filamin Calponin Homology 1 Domain

(2013) Ziba Razinia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

One number does not fit all: Mapping local variations in resolution in cryo-EM reconstructions

(2013) Giovanni Cardone et al.   JOURNAL OF STRUCTURAL BIOLOGY

Optimization of protein purification and characterization using Thermofluor screens

(2013) Stephane Boivin et al.   PROTEIN EXPRESSION AND PURIFICATION

Filamins in Mechanosensing and Signaling

(2012) Ziba Razinia et al.   Annual Review of Biophysics

Arg/Abl2 Modulates the Affinity and Stoichiometry of Binding of Cortactin to F-Actin

(2012) Stacey M. MacGrath et al.   BIOCHEMISTRY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Utrophin ABD binds to F-actin in an open conformation

(2012) Mike J.F. Broderick et al.   FEBS Open Bio

The E3 ubiquitin ligase specificity subunit ASB2  targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain

(2011) Z. Razinia et al.   JOURNAL OF CELL SCIENCE

Large-scale opening of utrophin's tandem calponin homology (CH) domains upon actin binding by an induced-fit mechanism

(2011) A. Y. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The filamins

(2011) Fumihiko Nakamura et al.   Cell Adhesion & Migration

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Opening of tandem calponin homology domains regulates their affinity for F-actin

(2010) Vitold E Galkin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the human filamin A actin-binding domain

(2009) Salla Ruskamo et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

electronic Ligand Builder and Optimization Workbench(eLBOW): a tool for ligand coordinate and restraint generation

(2009) Nigel W. Moriarty et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders†

(2009) Alice R. Clark et al.   HUMAN MOLECULAR GENETICS

Plectin Isoform-dependent Regulation of Keratin-Integrin α6β4 Anchorage via Ca2+/Calmodulin

(2009) Julius Kostan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disease-associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains

(2009) Gregory M. Sawyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Bilateral periventricular nodular heterotopia in France: frequency of mutations in FLNA, phenotypic heterogeneity and spectrum of mutations

(2009) G Sole et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

ASB2 targets filamins A and B to proteasomal degradation

(2008) M. L. Heuze et al.   BLOOD

Novel structural insights into F-actin-binding and novel functions of calponin homology domains

(2008) Björn Sjöblom et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

High-resolution cryo-EM structure of the F-actin-fimbrin/plastin ABD2 complex

(2008) V. E. Galkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA