Sustained active site rigidity during synthesis by human DNA polymerase μ

Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism

(2013) Jérôme Gouge et al.   JOURNAL OF MOLECULAR BIOLOGY

The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure

(2012) Christopher C. Valley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA-binding determinants promoting NHEJ by human Polµ

(2012) Maria Jose Martin et al.   NUCLEIC ACIDS RESEARCH

The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ

(2012) Rajendrakumar A. Gosavi et al.   NUCLEIC ACIDS RESEARCH

The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

(2011) Eugene Y. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Insights into DNA Polymerase Deterrents for Ribonucleotide Insertion

(2011) Nisha A. Cavanaugh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis

(2011) Ajay Ummat et al.   JOURNAL OF MOLECULAR BIOLOGY

Replication infidelity via a mismatch with Watson–Crick geometry

(2011) Katarzyna Bebenek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Modeling DNA Polymerase μ Motions: Subtle Transitions before Chemistry

(2010) Yunlang Li et al.   BIOPHYSICAL JOURNAL

Lack of DNA polymerase μ affects the kinetics of DNA double-strand break repair and impacts on cellular senescence

(2010) Romain Chayot et al.   DNA REPAIR

Structure and mechanism of human DNA polymerase η

(2010) Christian Biertümpfel et al.   NATURE

Loop 1 modulates the fidelity of DNA polymerase  

(2010) K. Bebenek et al.   NUCLEIC ACIDS RESEARCH

DNA Polymerase β Substrate Specificity

(2009) William A. Beard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conferring a template-dependent polymerase activity to terminal deoxynucleotidyltransferase by mutations in the Loop1 region

(2009) Félix Romain et al.   NUCLEIC ACIDS RESEARCH

Limited terminal transferase in human DNA polymerase   defines the required balance between accuracy and efficiency in NHEJ

(2009) P. Andrade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered Hematopoiesis in Mice Lacking DNA Polymerase μ Is Due to Inefficient Double-Strand Break Repair

(2009) Daniel Lucas et al.   PLoS Genetics

A comparison of BRCT domains involved in nonhomologous end-joining: Introducing the solution structure of the BRCT domain of polymerase lambda

(2008) Geoffrey A. Mueller et al.   DNA REPAIR

Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III α-Subunit

(2008) Richard A. Wing et al.   JOURNAL OF MOLECULAR BIOLOGY

A Role for DNA Polymerase   in the Emerging DJH Rearrangements of the Postgastrulation Mouse Embryo

(2008) B. Gozalbo-Lopez et al.   MOLECULAR AND CELLULAR BIOLOGY

Structures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during Misincorporation

(2008) Vinod K. Batra et al.   MOLECULAR CELL

End-bridging is required for pol μ to efficiently promote repair of noncomplementary ends by nonhomologous end joining

(2008) Bryan J. Davis et al.   NUCLEIC ACIDS RESEARCH