Internal motions prime cIAP1 for rapid activation

Macromolecular juggling by ubiquitylation enzymes

(2013) Sonja Lorenz et al.   BMC BIOLOGY

An integrated high-throughput data acquisition system for biological solution X-ray scattering studies

(2012) Anne Martel et al.   JOURNAL OF SYNCHROTRON RADIATION

Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

(2012) Jonathan N. Pruneda et al.   MOLECULAR CELL

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

(2012) Anna Plechanovová et al.   NATURE

Targeting IAP proteins for therapeutic intervention in cancer

(2012) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

(2011) Matthew L Bentley et al.   EMBO JOURNAL

Smac Mimetics Activate the E3 Ligase Activity of cIAP1 Protein by Promoting RING Domain Dimerization

(2011) Rebecca Feltham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GUARDD: user-friendly MATLAB software for rigorous analysis of CPMG RD NMR data

(2011) Ian R. Kleckner et al.   JOURNAL OF BIOMOLECULAR NMR

CARD-Mediated Autoinhibition of cIAP1's E3 Ligase Activity Suppresses Cell Proliferation and Migration

(2011) Juanita Lopez et al.   MOLECULAR CELL

Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination

(2011) E. C. Dueber et al.   SCIENCE

Preparation of Distinct Ubiquitin Chain Reagents of High Purity and Yield

(2011) Ken C. Dong et al.   STRUCTURE

An introduction to NMR-based approaches for measuring protein dynamics

(2010) Ian R. Kleckner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Small-molecule pan-IAP antagonists: a patent review

(2010) John A Flygare et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation

(2008) Eugene Varfolomeev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment

(2008) Peter D. Mace et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL