The true core of RNA silencing revealed

The N domain of Argonaute drives duplex unwinding during RISC assembly

(2012) Pieter Bas Kwak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An alternative mode of microRNA target recognition

(2012) Sung Wook Chi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Crystal Structure of Human Argonaute2

(2012) N. T. Schirle et al.   SCIENCE

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

(2011) Eric Huntzinger et al.   NATURE REVIEWS GENETICS

Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein

(2011) A. Boland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain

(2011) Lei Zeng et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Recognition of 2′-O-Methylated 3′-End of piRNA by the PAZ Domain of a Piwi Protein

(2011) Bernd Simon et al.   STRUCTURE

Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein

(2010) Andreas Boland et al.   EMBO REPORTS

Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes

(2010) Shintaro Iwasaki et al.   MOLECULAR CELL

In Vitro Assembly of Plant RNA-Induced Silencing Complexes Facilitated by Molecular Chaperone HSP90

(2010) Taichiro Iki et al.   MOLECULAR CELL

Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2

(2010) Filipp Frank et al.   NATURE

Allosteric regulation of Argonaute proteins by miRNAs

(2010) Sergej Djuranovic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phosphorylation of human Argonaute proteins affects small RNA binding

(2010) Sabine Rüdel et al.   NUCLEIC ACIDS RESEARCH

Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains

(2010) Y. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

Enhancement of the Seed-Target Recognition Step in RNA Silencing by a PIWI/MID Domain Protein

(2009) James S. Parker et al.   MOLECULAR CELL

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

(2009) Yanli Wang et al.   NATURE

Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway

(2009) K. Miyoshi et al.   RNA

A C-terminal silencing domain in GW182 is essential for miRNA function

(2009) A. Eulalio et al.   RNA

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE

Structure of the guide-strand-containing argonaute silencing complex

(2008) Yanli Wang et al.   NATURE

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

(2008) Ana Eulalio et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY