Structure of an aprataxin–DNA complex with insights into AOA1 neurodegenerative disease

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation

(2010) Aaron Klug   Annual Review of Biochemistry

Aprataxin Tumor Levels Predict Response of Colorectal Cancer Patients to Irinotecan-based Treatment

(2010) H. Dopeso et al.   CLINICAL CANCER RESEARCH

Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5′ end processing during base excision repair

(2010) James M. Daley et al.   DNA REPAIR

The discovery of zinc fingers and their development for practical applications in gene regulation and genome manipulation

(2010) Aaron Klug   QUARTERLY REVIEWS OF BIOPHYSICS

Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance

(2009) Gaurang P. Deshpande et al.   DNA REPAIR

Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage

(2009) Janelle L. Harris et al.   HUMAN MOLECULAR GENETICS

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response

(2009) Olivier J. Becherel et al.   NUCLEIC ACIDS RESEARCH

Eukaryotic DNA Ligases: Structural and Functional Insights

(2008) Tom Ellenberger et al.   Annual Review of Biochemistry

Molecular Mechanism of DNA Deadenylation by the Neurological Disease Protein Aprataxin

(2008) Ulrich Rass et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defective DNA Ligation during Short-Patch Single-Strand Break Repair in Ataxia Oculomotor Apraxia 1

(2008) J. J. Reynolds et al.   MOLECULAR AND CELLULAR BIOLOGY

Single-strand break repair and genetic disease

(2008) Keith W. Caldecott   NATURE REVIEWS GENETICS