ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair

Mre11–Rad50–Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks

(2010) Gareth J. Williams et al.   DNA REPAIR

Involvement of F1296 and N1303 of CFTR in induced-fit conformational change in response to ATP binding at NBD2

(2010) Andras Szollosi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Turning enzymes ON with small molecules

(2010) Julie A Zorn et al.   Nature Chemical Biology

FoXS: a web server for rapid computation and fitting of SAXS profiles

(2010) D. Schneidman-Duhovny et al.   NUCLEIC ACIDS RESEARCH

Human RAD50 Deficiency in a Nijmegen Breakage Syndrome-like Disorder

(2009) Regina Waltes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

(2009) R. Scott Williams et al.   CELL

Structure and flexibility within proteins as identified through small angle X-ray scattering

(2009) M. Pelikan et al.   GENERAL PHYSIOLOGY AND BIOPHYSICS

Molecular disruption of RAD50 sensitizes human tumor cells to cisplatin-based chemotherapy

(2009) Waleed M. Abuzeid et al.   JOURNAL OF CLINICAL INVESTIGATION

Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)

(2009) Greg L Hura et al.   NATURE METHODS

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The P. furiosus Mre11/Rad50 Complex Promotes 5′ Strand Resection at a DNA Double-Strand Break

(2008) Ben B. Hopkins et al.   CELL

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

(2008) R. Scott Williams et al.   CELL

A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex

(2008) Aude Dupré et al.   Nature Chemical Biology

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

(2008) Elsa D Garcin et al.   Nature Chemical Biology