Protective autoantibodies in the rheumatic diseases: lessons for therapy

Natural antibody to apoptotic cell membranes inhibits the proinflammatory properties of lupus autoantibody immune complexes

(2012) Jaya Vas et al.   ARTHRITIS AND RHEUMATISM

How apoptotic cells aid in the removal of their own cold dead bodies

(2012) G Wickman et al.   CELL DEATH AND DIFFERENTIATION

IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE

(2012) Caroline Grönwall et al.   CLINICAL IMMUNOLOGY

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

(2012) Ulrike Harre et al.   JOURNAL OF CLINICAL INVESTIGATION

Natural IgM in Immune Equilibrium and Harnessing Their Therapeutic Potential

(2012) S. V. Kaveri et al.   JOURNAL OF IMMUNOLOGY

Carotid Atherosclerosis, Disease Measures, Oxidized Low-density Lipoproteins, and Atheroprotective Natural Antibodies for Cardiovascular Disease in Early Rheumatoid Arthritis -- An Inception Cohort Study

(2012) S. AJEGANOVA et al.   JOURNAL OF RHEUMATOLOGY

MAPK phosphatase-1 is required for regulatory natural autoantibody-mediated inhibition of TLR responses

(2012) C. Gronwall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

(2011) Yury I. Miller et al.   CIRCULATION RESEARCH

Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−

(2011) Daniel O. Griffin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Natural IgM Is Required for Suppression of Inflammatory Arthritis by Apoptotic Cells

(2011) C. A. Notley et al.   JOURNAL OF IMMUNOLOGY

The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia

(2010) L. A. van de Stadt et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor α production

(2010) Ming-Chi Lu et al.   ARTHRITIS AND RHEUMATISM

Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor

(2010) Jeremy Sokolove et al.   ARTHRITIS AND RHEUMATISM

Regulatory natural autoantibodies to apoptotic cells: Pallbearers and protectors

(2010) Gregg J. Silverman   ARTHRITIS AND RHEUMATISM

The Absence of Serum IgM Enhances the Susceptibility of Mice to Pulmonary Challenge with Cryptococcus neoformans

(2010) K. S. Subramaniam et al.   JOURNAL OF IMMUNOLOGY

Preclinical Rheumatoid Arthritis: Identification, Evaluation, and Future Directions for Investigation

(2010) Kevin D. Deane et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Low Levels of Antibodies Against Phosphorylcholine Predict Development of Stroke in a Population-Based Study From Northern Sweden

(2010) Roland Fiskesund et al.   STROKE

"Go upstream, young man": lessons learned from the p38 saga

(2009) D Hammaker et al.   ANNALS OF THE RHEUMATIC DISEASES

Definition of human autoimmunity — autoantibodies versus autoimmune disease

(2009) Ana Lleo et al.   AUTOIMMUNITY REVIEWS

Immunoglobulin M Is Required for Protection Against Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

(2009) Myles J. Lewis et al.   CIRCULATION

Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis

(2009) Natalia Wegner et al.   IMMUNOLOGICAL REVIEWS

Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: Effects on uptake of oxidized LDL in macrophages as a potential mechanism

(2009) Ulf de Faire et al.   JOURNAL OF AUTOIMMUNITY

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

(2009) Meng-Yun Chou et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of Dendritic Cells and Macrophages by an Anti-Apoptotic Cell Natural Antibody that Suppresses TLR Responses and Inhibits Inflammatory Arthritis

(2009) Y. Chen et al.   JOURNAL OF IMMUNOLOGY

IgM Antibodies to Apoptosis-Associated Determinants Recruit C1q and Enhance Dendritic Cell Phagocytosis of Apoptotic Cells

(2009) Yifang Chen et al.   JOURNAL OF IMMUNOLOGY

C1q Differentially Modulates Phagocytosis and Cytokine Responses during Ingestion of Apoptotic Cells by Human Monocytes, Macrophages, and Dendritic Cells

(2009) D. A. Fraser et al.   JOURNAL OF IMMUNOLOGY

Interleukin 17 (IL-17) Increases the Expression of Toll-like Receptor-2, 4, and 9 by Increasing IL-1  and IL-6 Production in Autoimmune Arthritis

(2009) J.-H. LEE et al.   JOURNAL OF RHEUMATOLOGY

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

(2009) D. M. Czajkowsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunity to Citrullinated Proteins in Rheumatoid Arthritis

(2008) Lars Klareskog et al.   Annual Review of Immunology

Genetic imprinting of autoantibody repertoires in systemic lupus erythematosus patients

(2008) G. J. Silverman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Dual role for B-1a cells in immunity to influenza virus infection

(2008) Youn Soo Choi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The innate immune system in SLE: type I interferons and dendritic cells

(2008) L Rönnblom et al.   LUPUS

Natural antibodies against phosphorylcholine as potential protective factors in SLE

(2008) J. Su et al.   RHEUMATOLOGY

Inhibiting complement activation on cells at the step of C3 cleavage

(2008) M. Kathryn Liszewski et al.   VACCINE

Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis

(2008) Xiaoyan Zhao et al.   ARTHRITIS RESEARCH & THERAPY

Nature and functions of autoantibodies

(2008) Keith Elkon et al.   Nature clinical practice. Rheumatology