Biologic agents in rheumatology: unmet issues after 200 trials and $200 billion sales

Outcome Reporting Among Drug Trials Registered in ClinicalTrials.gov

(2013) Florence T. Bourgeois   ANNALS OF INTERNAL MEDICINE

Mega-Trials for Blockbusters

(2013) John P. A. Ioannidis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Therapies for Active Rheumatoid Arthritis after Methotrexate Failure

(2013) James R. O'Dell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical study reports of randomised controlled trials: an exploratory review of previously confidential industry reports

(2013) Peter Doshi et al.   BMJ Open

Comparative effect sizes in randomised trials from less developed and more developed countries: meta-epidemiological assessment

(2013) O. A. Panagiotou et al.   BMJ-British Medical Journal

Lack of Head-to-head Trials and Fair Control Arms

(2012) Candice Estellat   ARCHIVES OF INTERNAL MEDICINE

Association of industry funding with the outcome and quality of randomized controlled trials of drug therapy for rheumatoid arthritis

(2012) Nasim A. Khan et al.   ARTHRITIS AND RHEUMATISM

Risk of Malignancies in Patients With Rheumatoid Arthritis Treated With Biologic Therapy

(2012) Maria A. Lopez-Olivo et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Indirect Treatment Comparison of Abatacept with Methotrexate Versus Other Biologic Agents for Active Rheumatoid Arthritis Despite Methotrexate Therapy in the United Kingdom

(2012) P. GUYOT et al.   JOURNAL OF RHEUMATOLOGY

Incomplete reporting of recruitment information in clinical trials of biologic agents for the treatment of rheumatoid arthritis: A review

(2012) Ismail Simsek et al.   ARTHRITIS CARE & RESEARCH

The First 2 Years of the European Medicines Agency's Policy on Access to Documents: Secret No Longer

(2012) Peter Doshi et al.   JAMA Internal Medicine

Tumor necrosis factor therapy and the risk of serious infection and malignancy in patients with early rheumatoid arthritis: A meta-analysis of randomized controlled trials

(2011) Andrew E. Thompson et al.   ARTHRITIS AND RHEUMATISM

Clinical trials in rheumatoid arthritis: a status report from the ClinicalTrials.gov website

(2011) Jisna R. Paul et al.   RHEUMATOLOGY INTERNATIONAL

The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Methodological Report Phase I

(2010) J. Funovits et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Recommendations for an update of 2003 European regulatory requirements for registration of drugs to be used in the treatment of RA

(2010) Josef S. Smolen et al.   CURRENT MEDICAL RESEARCH AND OPINION

What outcomes from pharmacologic treatments are important to people with rheumatoid arthritis? Creating the basis of a patient core set

(2010) T. Sanderson et al.   ARTHRITIS CARE & RESEARCH

Industry sponsorship and selection of comparators in randomized clinical trials

(2009) D. N. Lathyris et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The safety of anti-tumour necrosis factor treatments in rheumatoid arthritis: meta and exposure-adjusted pooled analyses of serious adverse events

(2008) J P Leombruno et al.   ANNALS OF THE RHEUMATIC DISEASES

Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations

(2008) D. Aletaha et al.   ARTHRITIS AND RHEUMATISM

Poor reporting of search strategy and conflict of interest in over 250 narrative and systematic reviews of two biologic agents in arthritis: A systematic review

(2008) Aimee Kendall Roundtree et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias

(2008) Kerry Dwan et al.   PLoS One