Etiology of osteoarthritis: genetics and synovial joint development

Skin Problems of the Stump in Lower Limb Amputees: 1. A Clinical Study

(2016) H Meulenbelt et al.   ACTA DERMATO-VENEREOLOGICA

Evaluation of a fibrillin 2 gene haplotype associated with hip dysplasia and incipient osteoarthritis in dogs

(2011) Steven G. Friedenberg et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

Osteoarthritis susceptibility genes influence the association between hip morphology and osteoarthritis

(2011) J. H. Waarsing et al.   ARTHRITIS AND RHEUMATISM

Distribution and Progression of Chondrocyte Damage in a Whole-Organ Model of Human Ankle Intra-Articular Fracture

(2011) Yuki Tochigi et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

(2011) Ingrid M B H van de Laar et al.   NATURE GENETICS

Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus

(2011) A.W. Dodd et al.   OSTEOARTHRITIS AND CARTILAGE

Association of the D repeat polymorphism in the ASPN gene with developmental dysplasia of the hip: a case-control study in Han Chinese

(2011) Dongquan Shi et al.   ARTHRITIS RESEARCH & THERAPY

Knee osteoarthritis, lumbar-disc degeneration and developmental dysplasia of the hip - an emerging genetic overlap

(2011) John Loughlin   ARTHRITIS RESEARCH & THERAPY

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

(2010) E. Evangelou et al.   ANNALS OF THE RHEUMATIC DISEASES

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

(2010) K. Panoutsopoulou et al.   ANNALS OF THE RHEUMATIC DISEASES

Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes

(2010) Ana M. Valdes et al.   ARTHRITIS AND RHEUMATISM

GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women

(2010) F. M. K. Williams et al.   ARTHRITIS AND RHEUMATISM

To Seek Shelter from the Wnt in Osteoarthritis? Wnt-Signaling as a Target for Osteoarthritis Therapy

(2010) Arjen B. Blom et al.   CURRENT DRUG TARGETS

The anatomical basis for a novel classification of osteoarthritis and allied disorders

(2010) Dennis McGonagle et al.   JOURNAL OF ANATOMY

Cloning and characterization of the osteoarthritis-associated gene DVWA

(2010) Masahiro Nakajima et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Evidence of association between GDF5 polymorphisms and congenital dislocation of the hip in a Caucasian population

(2010) K. Rouault et al.   OSTEOARTHRITIS AND CARTILAGE

Serum and urinary biochemical markers for knee and hip-osteoarthritis: a systematic review applying the consensus BIPED criteria

(2010) W.E. van Spil et al.   OSTEOARTHRITIS AND CARTILAGE

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium

(2010) H.J.M. Kerkhof et al.   OSTEOARTHRITIS AND CARTILAGE

Differential Genetic Regulation of Canine Hip Dysplasia and Osteoarthritis

(2010) Zhengkui Zhou et al.   PLoS One

Prediction model for knee osteoarthritis based on genetic and clinical information

(2010) Hiroshi Takahashi et al.   ARTHRITIS RESEARCH & THERAPY

Large-scale analysis of association betweenGDF5andFRZBvariants and osteoarthritis of the hip, knee, and hand

(2009) Evangelos Evangelou et al.   ARTHRITIS AND RHEUMATISM

Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development

(2009) C. B. Little et al.   ARTHRITIS AND RHEUMATISM

The Otto Aufranc Award: Identification of a 4 Mb Region on Chromosome 17q21 Linked to Developmental Dysplasia of the Hip in One 18-member, Multigeneration Family

(2009) George Feldman et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

The genetics of chronic inflammatory diseases

(2009) G. A. Heap et al.   HUMAN MOLECULAR GENETICS

Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations

(2009) I. Meulenbelt et al.   HUMAN MOLECULAR GENETICS

A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium

(2009) G Zhai et al.   JOURNAL OF MEDICAL GENETICS

The knee osteoarthritis susceptibility locus DVWA on chromosome 3p24.3 is the 5′ part of the split COL6A4 gene

(2009) Raimund Wagener et al.   MATRIX BIOLOGY

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE

Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis

(2009) Frank Echtermeyer et al.   NATURE MEDICINE

Do HOXB9 and COL1A1 genes play a role in congenital dislocation of the hip? Study in a Caucasian population

(2009) K. Rouault et al.   OSTEOARTHRITIS AND CARTILAGE

The association of proximal femoral shape and incident radiographic hip OA in elderly women

(2009) J.A. Lynch et al.   OSTEOARTHRITIS AND CARTILAGE

Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis

(2009) M. Blagojevic et al.   OSTEOARTHRITIS AND CARTILAGE

C/EBPβ Promotes Transition from Proliferation to Hypertrophic Differentiation of Chondrocytes through Transactivation of p57Kip2

(2009) Makoto Hirata et al.   PLoS One

An Expressed Fgf4 Retrogene Is Associated with Breed-Defining Chondrodysplasia in Domestic Dogs

(2009) H. G. Parker et al.   SCIENCE

Primary Osteoarthritis No Longer Primary: Three Subsets with Distinct Etiological, Clinical, and Therapeutic Characteristics

(2009) Gabriel Herrero-Beaumont et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Association of the Asporin D14 Allele with Lumbar-Disc Degeneration in Asians

(2008) You-Qiang Song et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide Association Scan Identifies a Prostaglandin-Endoperoxide Synthase 2 Variant Involved in Risk of Knee Osteoarthritis

(2008) Ana M. Valdes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study

(2008) R B A Vaes et al.   ANNALS OF THE RHEUMATIC DISEASES

Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations

(2008) A M Valdes et al.   ANNALS OF THE RHEUMATIC DISEASES

Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse

(2008) Benjamin D. Ward et al.   ARTHRITIS AND RHEUMATISM

Nonspherical femoral head shape (pistol grip deformity), neck shaft angle, and risk of hip osteoarthritis: A case-control study

(2008) Michael Doherty et al.   ARTHRITIS AND RHEUMATISM

Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis

(2008) Francesco Dell'Accio et al.   ARTHRITIS AND RHEUMATISM

Exclusion of COL2A1 and VDR as Developmental Dysplasia of the Hip Genes

(2008) Michele Rubini et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

New insights into osteoarthritis: early developmental features of an ageing-related disease

(2008) Steffan Daniël Bos et al.   CURRENT OPINION IN RHEUMATOLOGY

A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility

(2008) K. Chapman et al.   HUMAN MOLECULAR GENETICS

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

(2008) Ingrid Meulenbelt et al.   HUMAN MOLECULAR GENETICS

Hip Disease in the Young Adult: Current Concepts of Etiology and Surgical Treatment*

(2008) John C Clohisy et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Single high-energy impact load causes posttraumatic OA in young rabbits via a decrease in cellular metabolism

(2008) Joseph Borrelli et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis

(2008) Yoshinari Miyamoto et al.   NATURE GENETICS

Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians

(2008) U. Atif et al.   OSTEOARTHRITIS AND CARTILAGE

Prevalence of bone attrition on knee radiographs and MRI in a community-based cohort

(2008) S. Reichenbach et al.   OSTEOARTHRITIS AND CARTILAGE

A novel in vivo murine model of cartilage regeneration. Age and strain-dependent outcome after joint surface injury

(2008) N.M. Eltawil et al.   OSTEOARTHRITIS AND CARTILAGE

Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study

(2008) Jin Dai et al.   ARTHRITIS RESEARCH & THERAPY

The additive effect of individual genes in predicting risk of knee osteoarthritis

(2007) A M Valdes et al.   ANNALS OF THE RHEUMATIC DISEASES