Pharmacogenetics: implications for therapy in rheumatic diseases

Estrogens interfere with leflunomide modulation of cytokine production by human activated monocytes

(2010) Paola Montagna et al.   Annals of the New York Academy of Sciences

Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients

(2010) L. R. Coulthard et al.   ANNALS OF THE RHEUMATIC DISEASES

Associations between the C677T and A1298C Polymorphisms of MTHFR and the Efficacy and Toxicity of Methotrexate in Rheumatoid Arthritis

(2010) Young Ho Lee et al.   CLINICAL DRUG INVESTIGATION

Associations Between Tumor Necrosis Factor-  (TNF- ) -308 and -238 G/A Polymorphisms and Shared Epitope Status and Responsiveness to TNF-  Blockers in Rheumatoid Arthritis: A Metaanalysis Update

(2010) Y. H. LEE et al.   JOURNAL OF RHEUMATOLOGY

Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response

(2010) Catherine Potter et al.   Pharmacogenetics and Genomics

Conference Scene: The great debate: genome-wide association studies in pharmacogenetics research, good or bad?

(2010) Kent R Bailey et al.   PHARMACOGENOMICS

Are patients with intermediate TPMT activity at increased risk of myelosuppression when taking thiopurine medications?

(2010) Jenny E Higgs et al.   PHARMACOGENOMICS

Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis

(2010) Wouter M Kooloos et al.   PHARMACOGENOMICS

The effect ofESR1andESR2gene polymorphisms on the outcome of rheumatoid arthritis treatment with leflunomide

(2010) Violetta Dziedziejko et al.   PHARMACOGENOMICS

Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis

(2009) P B. Grabar et al.   ANNALS OF THE RHEUMATIC DISEASES

Monoclonal anti-CD20 antibodies: Mechanisms of action and monitoring of biological effects

(2009) Yves Renaudineau et al.   JOINT BONE SPINE

Sex hormones modulate the effects of Leflunomide on cytokine production by cultures of differentiated monocyte/macrophages and synovial macrophages from rheumatoid arthritis patients

(2009) Maurizio Cutolo et al.   JOURNAL OF AUTOIMMUNITY

Metaanalysis of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms Affecting Methotrexate Toxicity

(2009) M. C. FISHER et al.   JOURNAL OF RHEUMATOLOGY

The effect of exon (19C>A) dihydroorotate dehydrogenase gene polymorphism on rheumatoid arthritis treatment with leflunomide

(2009) Andrzej Pawlik et al.   PHARMACOGENOMICS

Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients

(2008) Petra Bohanec Grabar et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Azathioprine-induced fatal myelosuppression in systemic lupus erythematosus patient carrying TPMT*3C polymorphism

(2008) U. Boonsrirat et al.   LUPUS