Shaping the nervous system: role of the core planar cell polarity genes

Axon tracts guide zebrafish facial branchiomotor neuron migration through the hindbrain

(2013) S. J. Wanner et al.   DEVELOPMENT

C. elegans fmi-1/flamingo and Wnt pathway components interact genetically to control the anteroposterior neurite growth of the VD GABAergic neurons

(2013) Elvis Huarcaya Najarro et al.   DEVELOPMENTAL BIOLOGY

Vangl2, the planner cell polarity protein, is complexed with postsynaptic density protein PSD-95

(2013) Toshinori Yoshioka et al.   FEBS LETTERS

Planar cell polarity genes control the connectivity of enteric neurons

(2013) Valentina Sasselli et al.   JOURNAL OF CLINICAL INVESTIGATION

Atypical Cadherins Celsr1-3 Differentially Regulate Migration of Facial Branchiomotor Neurons in Mice

(2013) Y. Qu et al.   JOURNAL OF NEUROSCIENCE

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

(2013) Luc G T Morris et al.   NATURE GENETICS

Responses of hair follicle-associated structures to loss of planar cell polarity signaling

(2013) H. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting planar cell polarity in the inner ear

(2013) Jérôme Ezan et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

(2013) Yusong Guo et al.   eLife

Role of the planar cell polarity gene CELSR1 in neural tube defects and caudal agenesis

(2012) Redouane Allache et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects

(2012) Diana M. Juriloff et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Coordinated Ciliary Beating Requires Odf2-Mediated Polarization of Basal Bodies via Basal Feet

(2012) Koshi Kunimoto et al.   CELL

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

(2012) Tamako Nishimura et al.   CELL

PTK7 Regulates Myosin II Activity to Orient Planar Polarity in the Mammalian Auditory Epithelium

(2012) Jianyi Lee et al.   CURRENT BIOLOGY

Planar Polarity Specification through Asymmetric Subcellular Localization of Fat and Dachsous

(2012) Amy Brittle et al.   CURRENT BIOLOGY

Microtubules Enable the Planar Cell Polarity of Airway Cilia

(2012) Eszter K. Vladar et al.   CURRENT BIOLOGY

Propagation of Dachsous-Fat Planar Cell Polarity

(2012) Abhijit A. Ambegaonkar et al.   CURRENT BIOLOGY

Establishment of Global Patterns of Planar Polarity during Growth of the Drosophila Wing Epithelium

(2012) Andreas Sagner et al.   CURRENT BIOLOGY

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity

(2012) S. Saburi et al.   DEVELOPMENT

Separating planar cell polarity and Hippo pathway activities of the protocadherins Fat and Dachsous

(2012) H. Matakatsu et al.   DEVELOPMENT

Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear

(2012) A. P. Giese et al.   DEVELOPMENT

The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled

(2012) Derrick M. Glasco et al.   DEVELOPMENTAL BIOLOGY

DrosophilaCK1-γ,gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking

(2012) William J. Gault et al.   JOURNAL OF CELL BIOLOGY

Caenorhabditis elegans Flamingo Cadherin fmi-1 Regulates GABAergic Neuronal Development

(2012) E. H. Najarro et al.   JOURNAL OF NEUROSCIENCE

A Role for Atypical Cadherin Celsr3 in Hippocampal Maturation and Connectivity

(2012) J. Feng et al.   JOURNAL OF NEUROSCIENCE

Mechanical Control of Morphogenesis by Fat/Dachsous/Four-Jointed Planar Cell Polarity Pathway

(2012) F. Bosveld et al.   SCIENCE

Planar Cell Polarity and the Developmental Control of Cell Behavior in Vertebrate Embryos

(2011) John B. Wallingford   Annual Review of Cell and Developmental Biology

Vertebrate Segmentation: From Cyclic Gene Networks to Scoliosis

(2011) Olivier Pourquié   CELL

Intertissue Mechanical Stress Affects Frizzled-Mediated Planar Cell Polarity in the Drosophila Notum Epidermis

(2011) Patricio Olguín et al.   CURRENT BIOLOGY

Cell flow and tissue polarity patterns

(2011) Suzanne Eaton et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Principles of planar polarity in animal development

(2011) L. V. Goodrich et al.   DEVELOPMENT

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development

(2011) Y. Mao et al.   DEVELOPMENT

Defective neuroepithelial cell cohesion affects tangential branchiomotor neuron migration in the zebrafish neural tube

(2011) P. Stockinger et al.   DEVELOPMENT

Planar polarity pathway and Nance-Horan syndrome-like 1b have essential cell-autonomous functions in neuronal migration

(2011) G. S. Walsh et al.   DEVELOPMENT

Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements

(2011) D. S. Sepich et al.   DEVELOPMENT

Wnt/PCP proteins regulate stereotyped axon branch extension in Drosophila

(2011) J. Ng   DEVELOPMENT

The core planar cell polarity gene prickle interacts with flamingo to promote sensory axon advance in the Drosophila embryo

(2011) Eli M. Mrkusich et al.   DEVELOPMENTAL BIOLOGY

Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity

(2011) Ryan S. Gray et al.   DEVELOPMENTAL CELL

Vangl2 Promotes Wnt/Planar Cell Polarity-like Signaling by Antagonizing Dvl1-Mediated Feedback Inhibition in Growth Cone Guidance

(2011) Beth Shafer et al.   DEVELOPMENTAL CELL

The roles of the cadherins Fat and Dachsous in planar polarity specification inDrosophila

(2011) Chloe Thomas et al.   DEVELOPMENTAL DYNAMICS

The seven-pass transmembrane cadherin Flamingo controls dendritic self-avoidance via its binding to a LIM domain protein, Espinas, in Drosophila sensory neurons

(2011) D. Matsubara et al.   GENES & DEVELOPMENT

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia

(2011) J. B. Wallingford et al.   GENES & DEVELOPMENT

FZD6is a novel gene for human neural tube defects

(2011) Patrizia De Marco et al.   HUMAN MUTATION

Mutations in the planar cell polarity genesCELSR1andSCRIBare associated with the severe neural tube defect craniorachischisis

(2011) Alexis Robinson et al.   HUMAN MUTATION

Identification and characterization of novel rare mutations in the planar cell polarity genePRICKLE1in human neural tube defects

(2011) Ciprian M. Bosoi et al.   HUMAN MUTATION

Prickle2 is localized in the postsynaptic density and interacts with PSD-95 and NMDA receptors in the brain

(2011) Y. Hida et al.   JOURNAL OF BIOCHEMISTRY

Actin and microtubules drive differential aspects of planar cell polarity in multiciliated cells

(2011) Michael E. Werner et al.   JOURNAL OF CELL BIOLOGY

The Wnt5/Planar Cell Polarity Pathway Regulates Axonal Development of the Drosophila Mushroom Body Neuron

(2011) K. Shimizu et al.   JOURNAL OF NEUROSCIENCE

Regulation of basal body and ciliary functions by Diversin

(2011) Takayuki Yasunaga et al.   MECHANISMS OF DEVELOPMENT

Mitotic internalization of planar cell polarity proteins preserves tissue polarity

(2011) Danelle Devenport et al.   NATURE CELL BIOLOGY

Golden Goal collaborates with Flamingo in conferring synaptic-layer specificity in the visual system

(2011) Satoko Hakeda-Suzuki et al.   NATURE NEUROSCIENCE

Control of Neuronal Morphology by the Atypical Cadherin Fat3

(2011) Michael R. Deans et al.   NEURON

Translating cell polarity into tissue elongation

(2011) Athea Vichas et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Fifteen formins for an actin filament: A molecular view on the regulation of human formins

(2010) André Schönichen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila

(2010) Benoît Aigouy et al.   CELL

Planar cell polarity signaling, cilia and polarized ciliary beating

(2010) John B Wallingford   CURRENT OPINION IN CELL BIOLOGY

Planar cell polarity signaling in neural development

(2010) Fadel Tissir et al.   CURRENT OPINION IN NEUROBIOLOGY

Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II

(2010) Y. Hirota et al.   DEVELOPMENT

When whorls collide: the development of hair patterns in frizzled 6 mutant mice

(2010) Y. Wang et al.   DEVELOPMENT

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

(2010) C. Wansleeben et al.   DEVELOPMENT

The Flamingo ortholog FMI-1 controls pioneer-dependent navigation of follower axons in C. elegans

(2010) A. Steimel et al.   DEVELOPMENT

The Fz-Dsh Planar Cell Polarity Pathway Induces Oriented Cell Division via Mud/NuMA in Drosophila and Zebrafish

(2010) Marion Ségalen et al.   DEVELOPMENTAL CELL

Prickle1b mediates interpretation of migratory cues during zebrafish facial branchiomotor neuron migration

(2010) Oni M. Mapp et al.   DEVELOPMENTAL DYNAMICS

Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation

(2010) J. Singh et al.   GENES & DEVELOPMENT

Cilia Organize Ependymal Planar Polarity

(2010) Z. Mirzadeh et al.   JOURNAL OF NEUROSCIENCE

Wnt/Planar Cell Polarity Signaling Controls the Anterior-Posterior Organization of Monoaminergic Axons in the Brainstem

(2010) A. G. Fenstermaker et al.   JOURNAL OF NEUROSCIENCE

Basal enrichment within neuroepithelia suggests novel function(s) for Celsr1 protein

(2010) Caroline J. Formstone et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

(2010) Hai Song et al.   NATURE

Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia

(2010) Boris Guirao et al.   NATURE CELL BIOLOGY

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

(2010) Fadel Tissir et al.   NATURE NEUROSCIENCE

The PCP Pathway Instructs the Planar Orientation of Ciliated Cells in the Xenopus Larval Skin

(2009) Brian Mitchell et al.   CURRENT BIOLOGY

Phosphorylation of the Tumor Suppressor Fat Is Regulated by Its Ligand Dachsous and the Kinase Discs Overgrown

(2009) Richelle Sopko et al.   CURRENT BIOLOGY

Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain

(2009) Blue B. Lake et al.   JOURNAL OF CELL BIOLOGY

Inactivation of Chibby affects function of motile airway cilia

(2009) Vera A. Voronina et al.   JOURNAL OF CELL BIOLOGY

Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse

(2009) Aurélia Ravni et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Protocadherin Gene Celsr3 Is Required for Interneuron Migration in the Mouse Forebrain

(2009) G. Ying et al.   MOLECULAR AND CELLULAR BIOLOGY

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

(2009) Janna Merte et al.   NATURE CELL BIOLOGY

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q– syndrome

(2009) Jillian L Barlow et al.   NATURE MEDICINE

Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases

(2009) Valerie Vivancos et al.   Neural Development

Development of the vertebrate central nervous system: formation of the neural tube

(2009) Nicholas D. E. Greene et al.   PRENATAL DIAGNOSIS

Cell division orientation and planar cell polarity pathways

(2009) Marion Segalen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-Recessive Progressive Myoclonus Epilepsy-Ataxia Syndrome

(2008) Alexander G. Bassuk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cilia orientation and the fluid mechanics of development

(2008) Wallace F Marshall et al.   CURRENT OPINION IN CELL BIOLOGY

The atypical cadherin Flamingo is required for sensory axon advance beyond intermediate target cells

(2008) Martin C. Steinel et al.   DEVELOPMENTAL BIOLOGY

Mutations inHydinimpair ciliary motility in mice

(2008) Karl-Ferdinand Lechtreck et al.   JOURNAL OF CELL BIOLOGY

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

(2008) Danelle Devenport et al.   NATURE CELL BIOLOGY

Do the protocadherins Fat and Dachsous link up to determine both planar cell polarity and the dimensions of organs?

(2008) Peter A. Lawrence et al.   NATURE CELL BIOLOGY

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease

(2008) Sakura Saburi et al.   NATURE GENETICS

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

(2008) Tae Joo Park et al.   NATURE GENETICS

The Cadherin Flamingo Mediates Level-Dependent Interactions that Guide Photoreceptor Target Choice in Drosophila

(2008) Pei-Ling Chen et al.   NEURON

The stumpy gene is required for mammalian ciliogenesis

(2008) T. Town et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Four-jointed Is a Golgi Kinase That Phosphorylates a Subset of Cadherin Domains

(2008) H. O. Ishikawa et al.   SCIENCE

Early Forebrain Wiring: Genetic Dissection Using Conditional Celsr3 Mutant Mice

(2008) L. Zhou et al.   SCIENCE