Journal
NATURE REVIEWS NEPHROLOGY
Volume 9, Issue 12, Pages 700-702Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrneph.2013.212
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In a recent study using transgenic mice with inducible podocyte-specific expression of tagged albumin, Tenten and colleagues report transtubular transport of albumin, possibly mediated by the neonatal Fc receptor. This study raises several questions about the physiological importance of this potential pathway and the implications for albuminuria in renal disease.
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