RNA viruses and the host microRNA machinery

C. elegans piRNAs Mediate the Genome-wide Surveillance of Germline Transcripts

(2012) Heng-Chi Lee et al.   CELL

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

piRNAs Can Trigger a Multigenerational Epigenetic Memory in the Germline of C. elegans

(2012) Alyson Ashe et al.   CELL

piRNAs Initiate an Epigenetic Memory of Nonself RNA in the C. elegans Germline

(2012) Masaki Shirayama et al.   CELL

Degradation of Host MicroRNAs by Poxvirus Poly(A) Polymerase Reveals Terminal RNA Methylation as a Protective Antiviral Mechanism

(2012) Simone Backes et al.   Cell Host & Microbe

Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines

(2012) H. Ishizu et al.   GENES & DEVELOPMENT

Influenza A Virus Infection of Human Respiratory Cells Induces Primary MicroRNA Expression

(2012) William A. Buggele et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA Targeting of Neurotropic Flavivirus: Effective Control of Virus Escape and Reversion to Neurovirulent Phenotype

(2012) B. L. Heiss et al.   JOURNAL OF VIROLOGY

RNA-guided genetic silencing systems in bacteria and archaea

(2012) Blake Wiedenheft et al.   NATURE

Oncolytic virotherapy

(2012) Stephen J Russell et al.   NATURE BIOTECHNOLOGY

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors

(2012) Jun Xie et al.   NATURE METHODS

High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries

(2012) Gavriel Mullokandov et al.   NATURE METHODS

An alternative mode of microRNA target recognition

(2012) Sung Wook Chi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex

(2012) T. Shimakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA virus microRNA that mimics a B-cell oncomiR

(2012) R. P. Kincaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses

(2012) Ryan A. Langlois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for a cytoplasmic microprocessor of pri-miRNAs

(2012) J. S. Shapiro et al.   RNA

Replication in Cells of Hematopoietic Origin Is Necessary for Dengue Virus Dissemination

(2012) Alissa M. Pham et al.   PLoS Pathogens

Degradation of Cellular miR-27 by a Novel, Highly Abundant Viral Transcript Is Important for Efficient Virus Replication In Vivo

(2012) Lisa Marcinowski et al.   PLoS Pathogens

Transgenerational Inheritance of an Acquired Small RNA-Based Antiviral Response in C. elegans

(2011) Oded Rechavi et al.   CELL

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

(2011) Frederick Anokye-Danso et al.   Cell Stem Cell

Viruses and microRNAs: RISCy interactions with serious consequences

(2011) B. R. Cullen   GENES & DEVELOPMENT

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay

(2011) Christof Fellmann et al.   MOLECULAR CELL

MicroRNA-sensitive Oncolytic Measles Viruses for Cancer-specific Vector Tropism

(2011) Mathias F Leber et al.   MOLECULAR THERAPY

In Vivo Delivery of Cytoplasmic RNA Virus-derived miRNAs

(2011) Ryan A Langlois et al.   MOLECULAR THERAPY

PIWI-interacting small RNAs: the vanguard of genome defence

(2011) Mikiko C. Siomi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels

(2011) Yamina Bennasser et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells

(2011) M. Hussain et al.   NUCLEIC ACIDS RESEARCH

Masking the 5' terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex

(2011) E. S. Machlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target

(2011) V. Libri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome Half-Life Dynamics in Living Human Cells

(2011) E. Eden et al.   SCIENCE

Integrative Deep Sequencing of the Mouse Lung Transcriptome Reveals Differential Expression of Diverse Classes of Small RNAs in Response to Respiratory Virus Infection

(2011) X. Peng et al.   mBio

Herpesvirus microRNAs: phenotypes and functions

(2011) Bryan R Cullen   Current Opinion in Virology

Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver

(2010) Dirk Grimm et al.   JOURNAL OF CLINICAL INVESTIGATION

Insertion of MicroRNA Targets into the Flavivirus Genome Alters Its Highly Neurovirulent Phenotype

(2010) B. L. Heiss et al.   JOURNAL OF VIROLOGY

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

(2010) Chanseok Shin et al.   MOLECULAR CELL

CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea

(2010) Luciano A. Marraffini et al.   NATURE REVIEWS GENETICS

Functional microRNA generated from a cytoplasmic RNA virus

(2010) Harald Rouha et al.   NUCLEIC ACIDS RESEARCH

Engineered RNA viral synthesis of microRNAs

(2010) A. Varble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza A virus-generated small RNAs regulate the switch from transcription to replication

(2010) J. T. Perez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noncanonical cytoplasmic processing of viral microRNAs

(2010) J. S. Shapiro et al.   RNA

Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA

(2010) D. Cazalla et al.   SCIENCE

Target RNA-Directed Trimming and Tailing of Small Silencing RNAs

(2010) S. L. Ameres et al.   SCIENCE

Six RNA Viruses and Forty-One Hosts: Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems

(2010) Poornima Parameswaran et al.   PLoS Pathogens

Small silencing RNAs: State-of-the-art

(2009) Dirk Grimm   ADVANCED DRUG DELIVERY REVIEWS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Coherent but overlapping expression of microRNAs and their targets during vertebrate development

(2009) A. Shkumatava et al.   GENES & DEVELOPMENT

Attenuation of Vesicular Stomatitis Virus Encephalitis through MicroRNA Targeting

(2009) E. J. Kelly et al.   JOURNAL OF VIROLOGY

Low-level shRNA Cytotoxicity Can Contribute to MYC-induced Hepatocellular Carcinoma in Adult Mice

(2009) Shelly Beer et al.   MOLECULAR THERAPY

Antiviral immunity in Drosophila requires systemic RNA interference spread

(2009) Maria-Carla Saleh et al.   NATURE

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Embryonic stem cell–specific microRNAs promote induced pluripotency

(2009) Robert L Judson et al.   NATURE BIOTECHNOLOGY

MicroRNA-mediated species-specific attenuation of influenza A virus

(2009) Jasmine T Perez et al.   NATURE BIOTECHNOLOGY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

(2009) Aimee L. Jackson et al.   NATURE REVIEWS DRUG DISCOVERY

Harnessing Endogenous miRNAs to Control Virus Tissue Tropism as a Strategy for Developing Attenuated Virus Vaccines

(2008) Dwight Barnes et al.   Cell Host & Microbe

Position-Dependent Function for a Tandem MicroRNA miR-122-Binding Site Located in the Hepatitis C Virus RNA Genome

(2008) Catherine L. Jopling et al.   Cell Host & Microbe

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Engineered lentiviral vector targeting astrocytesIn vivo

(2008) Angélique Colin et al.   GLIA

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A let-7 MicroRNA-sensitive Vesicular Stomatitis Virus Demonstrates Tumor-specific Replication

(2008) Robert E Edge et al.   MOLECULAR THERAPY

Artificial MicroRNAs as siRNA Shuttles: Improved Safety as Compared to shRNAs In vitro and In vivo

(2008) Ryan L Boudreau et al.   MOLECULAR THERAPY

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

(2008) Mark E. Kleinman et al.   NATURE

Stable knockdown of microRNA in vivo by lentiviral vectors

(2008) Bernhard Gentner et al.   NATURE METHODS

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

(2008) J. L. McBride et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

(2008) M. Landthaler et al.   RNA

Merkel cell polyomavirus encodes a microRNA with the ability to autoregulate viral gene expression

(2008) Gil Ju Seo et al.   VIROLOGY