The microbiology of asthma

Pulmonary Surfactant Protein A Regulates TLR Expression and Activity in Human Macrophages

(2014) L. N. Henning et al.   JOURNAL OF IMMUNOLOGY

Evidence for a Causal Relationship between Allergic Sensitization and Rhinovirus Wheezing in Early Life

(2011) Daniel J. Jackson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity

(2011) Huihui Chen et al.   CELL

IL-28A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease

(2011) Ourania Koltsida et al.   EMBO Molecular Medicine

Treatment with the TLR7 agonist R848 induces regulatory T-cell-mediated suppression of established asthma symptoms

(2011) Linh Pham Van et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4–dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways

(2011) De-Quan Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthma

(2011) Theresa W. Guilbert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C

(2011) Yury A Bochkov et al.   NATURE MEDICINE

Exposure to Environmental Microorganisms and Childhood Asthma

(2011) Markus J. Ege et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Randomized Trial of Omalizumab (Anti-IgE) for Asthma in Inner-City Children

(2011) William W. Busse et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial-induced protection against allergic inflammation through a multicomponent immunoregulatory mechanism

(2011) C. Nembrini et al.   THORAX

Viruses and bacteria in acute asthma exacerbations - A GA2LEN-DARE* systematic review

(2010) N. G. Papadopoulos et al.   ALLERGY

Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren

(2010) Mitsuyoshi Urashima et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Toll-like Receptor 7–triggered Immune Response in the Lung Mediates Acute and Long-Lasting Suppression of Experimental Asthma

(2010) Charoula Xirakia et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

(2010) H. Okada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Potentially pathogenic bacteria cultured from the sputum of stable asthmatics are associated with increased 8-isoprostane and airway neutrophilia

(2010) Lisa G. Wood et al.   FREE RADICAL RESEARCH

TSLP from RSV-stimulated rat airway epithelial cells activates myeloid dendritic cells

(2010) Jianou Qiao et al.   IMMUNOLOGY AND CELL BIOLOGY

The effect of respiratory syncytial virus on subsequent recurrent wheezing in atopic and nonatopic children

(2010) Eric A.F. Simões et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study

(2010) John M. Brehm et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

(2010) Yvonne J. Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NK Cell Deficiency Predisposes to Viral-Induced Th2-Type Allergic Inflammation via Epithelial-Derived IL-25

(2010) G. E. Kaiko et al.   JOURNAL OF IMMUNOLOGY

Rhinovirus Infection of Allergen-Sensitized and -Challenged Mice Induces Eotaxin Release from Functionally Polarized Macrophages

(2010) D. R. Nagarkar et al.   JOURNAL OF IMMUNOLOGY

Randomized placebo-controlled trial of lactobacillus on asthmatic children with allergic rhinitis

(2010) Yue-Sheng Chen et al.   PEDIATRIC PULMONOLOGY

Risk Factors for Invasive Pneumococcal Disease in Children in the Era of Conjugate Vaccine Use

(2010) T. Pilishvili et al.   PEDIATRICS

Disordered Microbial Communities in Asthmatic Airways

(2010) Markus Hilty et al.   PLoS One

Rhinovirus infection induces expression of airway remodelling factors in vitro and in vivo

(2010) Curtis KUO et al.   RESPIROLOGY

Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-  in bronchial epithelial cells from donors with asthma

(2010) L. Uller et al.   THORAX

Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life

(2010) N. Sigurs et al.   THORAX

Risk of invasive pneumococcal infections among working age adults with asthma

(2010) P. Klemets et al.   THORAX

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of skin prick tests with specific serum immunoglobulin E in the diagnosis of fungal sensitization in patients with severe asthma

(2009) B. R. O'Driscoll et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Pneumococcal carriage is more common in asthmatic than in non-asthmatic young men

(2009) Ulla Jounio et al.   Clinical Respiratory Journal

The severity-dependent relationship of infant bronchiolitis on the risk and morbidity of early childhood asthma

(2009) Kecia N. Carroll et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects

(2009) Nilceia Lopez-Souza et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbeAcinetobacter lwoffiiF78

(2009) Melanie L. Conrad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma

(2009) Y A Bochkov et al.   Mucosal Immunology

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Surface hydrophobin prevents immune recognition of airborne fungal spores

(2009) Vishukumar Aimanianda et al.   NATURE

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

The Burden of Respiratory Syncytial Virus Infection in Young Children

(2009) Caroline Breese Hall et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and tolerability of montelukast in placebo-controlled pediatric studies and their open-label extensions

(2009) Hans Bisgaard et al.   PEDIATRIC PULMONOLOGY

The effects of antifungal therapy on severe asthma with fungal sensitization and allergic bronchopulmonary aspergillosis

(2009) Alessandro C. PASQUALOTTO et al.   RESPIROLOGY

Sequencing and Analyses of All Known Human Rhinovirus Genomes Reveal Structure and Evolution

(2009) Ann C. Palmenberg et al.   SCIENCE

Genetic association study for RSV bronchiolitis in infancy at the 5q31 cytokine cluster

(2009) J T Forton et al.   THORAX

T-cell activation during exacerbations: a longitudinal study in refractory asthma

(2008) E. Mamessier et al.   ALLERGY

Human Rhinovirus 1B Exposure Induces Phosphatidylinositol 3-Kinase–dependent Airway Inflammation in Mice

(2008) Dawn C. Newcomb et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Wheezing Rhinovirus Illnesses in Early Life Predict Asthma Development in High-Risk Children

(2008) Daniel J. Jackson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interleukin-10/Interleukin-5 Responses at Birth Predict Risk for Respiratory Infections in Children with Atopic Family History

(2008) Guicheng Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Randomized Controlled Trial of Oral Antifungal Treatment for Severe Asthma with Fungal Sensitization

(2008) David W. Denning et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bioluminescent Aspergillus fumigatus, a New Tool for Drug Efficiency Testing and In Vivo Monitoring of Invasive Aspergillosis

(2008) M. Brock et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Diversity and seasonal dynamics of bacterial community in indoor environment

(2008) Helena Rintala et al.   BMC MICROBIOLOGY

Respiratory syncytial virus infection provokes airway remodelling in allergen-exposed mice in absence of prior allergen sensitization

(2008) S. Tourdot et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Predominance of Gram-positive bacteria in house dust in the low-allergy risk Russian Karelia

(2008) Jaakko Pakarinen et al.   ENVIRONMENTAL MICROBIOLOGY

Global strategy for asthma management and prevention: GINA executive summary

(2008) E. D. Bateman et al.   EUROPEAN RESPIRATORY JOURNAL

The effects of meteorological factors on airborne fungal spore concentration in two areas differing in urbanisation level

(2008) M. Oliveira et al.   INTERNATIONAL JOURNAL OF BIOMETEOROLOGY

Toll-like receptor heterodimer variants protect from childhood asthma

(2008) Michael S.D. Kormann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Virus-specific IgE enhances airway responsiveness on reinfection with respiratory syncytial virus in newborn mice

(2008) Azzeddine Dakhama et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Polymorphisms in Toll‐Like Receptor Genes and Susceptibility to Pulmonary Aspergillosis

(2008) A. Carvalho et al.   JOURNAL OF INFECTIOUS DISEASES

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

(2008) Aurelien Trompette et al.   NATURE

A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

(2008) Robert J Snelgrove et al.   NATURE IMMUNOLOGY

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

(2008) Nathan W Bartlett et al.   NATURE MEDICINE

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

(2008) S. D. Message et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of a soluble TNF  receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial

(2008) J B Morjaria et al.   THORAX

IRF-1Gene Variations Influence IgE Regulation and Atopy

(2007) Michaela Schedel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MUC1 Mucin Is a Negative Regulator of Toll-Like Receptor Signaling

(2007) Keiko Ueno et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY