Genome–virome interactions: examining the role of common viral infections in complex disease

Filoviruses are ancient and integrated into mammalian genomes

(2011) Derek J Taylor et al.   BMC EVOLUTIONARY BIOLOGY

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Enterovirus Infection and Progression From Islet Autoimmunity to Type 1 Diabetes: The Diabetes and Autoimmunity Study in the Young (DAISY)

(2010) L. C. Stene et al.   DIABETES

The changing epidemiology of type 1 diabetes: why is it going through the roof?

(2010) Kendra Vehik et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Virus/Allergen Interactions and Exacerbations of Asthma

(2010) Kirsten M. Kloepfer et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

New Human Rhinovirus Species and Their Significance in Asthma Exacerbation and Airway Remodeling

(2010) E. Kathryn Miller   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Weekly monitoring of children with asthma for infections and illness during common cold seasons

(2010) Jaime P. Olenec et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The ABCs of Rhinoviruses, Wheezing, and Asthma

(2010) J. E. Gern   JOURNAL OF VIROLOGY

Decreased activation of inflammatory networks during acute asthma exacerbations is associated with chronic airflow obstruction

(2010) A Bosco et al.   Mucosal Immunology

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

(2010) Matthias Heinig et al.   NATURE

Endogenous non-retroviral RNA virus elements in mammalian genomes

(2010) Masayuki Horie et al.   NATURE

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Allergic sensitization is associated with rhinovirus-, but not other virus-, induced wheezing in children

(2010) T. Jartti et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes

(2010) Kate Downes et al.   PLoS One

Enteroviruses and type 1 diabetes: towards a better understanding of the relationship

(2010) Hela Jaïdane et al.   REVIEWS IN MEDICAL VIROLOGY

Enteroviruses in the pathogenesis of type 1 diabetes

(2010) Sisko Tauriainen et al.   Seminars in Immunopathology

Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-  in bronchial epithelial cells from donors with asthma

(2010) L. Uller et al.   THORAX

Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium

(2010) Louise Slater et al.   PLoS Pathogens

Redefining Chronic Viral Infection

(2009) Herbert W. Virgin et al.   CELL

Multiplex Molecular Detection of Respiratory Pathogens in Children With Asthma Exacerbation

(2009) Ting Fan Leung et al.   CHEST

Genetics and epidemiology: asthma and infection

(2009) Nathan W Bartlett et al.   Current Opinion in Allergy and Clinical Immunology

Gene–environmental interaction in the development of atopic asthma: new developments

(2009) Peter N Le Souëf   Current Opinion in Allergy and Clinical Immunology

Asthma genetics and genomics 2009

(2009) Scott T Weiss et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Molecular Detection of Murine Norovirus from Experimentally and Spontaneously Infected Mice

(2009) Kazuo GOTO et al.   EXPERIMENTAL ANIMALS

Rethinking the Pathogenesis of Asthma

(2009) Stephen T. Holgate et al.   IMMUNITY

Innate Cells and T Helper 2 Cell Immunity in Airway Inflammation

(2009) Nora A. Barrett et al.   IMMUNITY

Predictors of sub-clinical enterovirus infections in infants: a prospective cohort study

(2009) Elisabet Witsø et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Identification of Loss of Function Mutations in Human Genes Encoding RIG-I and MDA5

(2009) Taeko Shigemoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Double-Stranded RNA Pattern Recognition Receptors in Rhinovirus-Induced Airway Epithelial Cell Responses

(2009) Q. Wang et al.   JOURNAL OF IMMUNOLOGY

A virus–gene collaboration

(2009) Matthias von Herrath   NATURE

Autophagy genes in immunity

(2009) Herbert W Virgin et al.   NATURE IMMUNOLOGY

Influence of microbial environment on autoimmunity

(2009) Alexander V Chervonsky   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Genetics of Type 1A Diabetes

(2009) Patrick Concannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diversity in the bronchial epithelial cell response to infection with different rhinovirus strains

(2009) Peter A.B. WARK et al.   RESPIROLOGY

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

The complete genome of klassevirus - a novel picornavirus in pediatric stool

(2009) Alexander L Greninger et al.   Virology Journal

Wheezing Rhinovirus Illnesses in Early Life Predict Asthma Development in High-Risk Children

(2008) Daniel J. Jackson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

Rhinovirus and the initiation of asthma

(2008) James E Gern   Current Opinion in Allergy and Clinical Immunology

IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

(2008) S. Liu et al.   HUMAN MOLECULAR GENETICS

Rhinovirus Transmission within Families with Children: Incidence of Symptomatic and Asymptomatic Infections

(2008) Ville Peltola et al.   JOURNAL OF INFECTIOUS DISEASES

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

(2008) Edy Y Kim et al.   NATURE MEDICINE

Concordance for Islet Autoimmunity among Monozygotic Twins

(2008) Maria J. Redondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Respiratory Viruses in Asymptomatic Subjects

(2008) Tuomas Jartti et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

(2008) S. D. Message et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA