Chromatin and the genome integrity network

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

(2012) Martijn S Luijsterburg et al.   EMBO JOURNAL

Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination

(2012) F. R. Neumann et al.   GENES & DEVELOPMENT

SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication

(2012) R. Betous et al.   GENES & DEVELOPMENT

The Saccharomyces cerevisiae Chromatin Remodeler Fun30 Regulates DNA End Resection and Checkpoint Deactivation

(2012) V. V. Eapen et al.   MOLECULAR AND CELLULAR BIOLOGY

Replisome Stability at Defective DNA Replication Forks Is Independent of S Phase Checkpoint Kinases

(2012) Giacomo De Piccoli et al.   MOLECULAR CELL

The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends

(2012) Xuefeng Chen et al.   NATURE

Intrinsic coupling of lagging-strand synthesis to chromatin assembly

(2012) Duncan J. Smith et al.   NATURE

Increased chromosome mobility facilitates homology search during recombination

(2012) Judith Miné-Hattab et al.   NATURE CELL BIOLOGY

Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery

(2012) Vincent Dion et al.   NATURE CELL BIOLOGY

Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1

(2012) N. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair

(2011) Irene Chiolo et al.   CELL

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4

(2011) Triantaffyllos Gkikopoulos et al.   EMBO JOURNAL

ATP-Dependent Chromatin Remodeling Factors Tune S Phase Checkpoint Activity

(2011) T. J. Au et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination

(2011) Kyosuke Nakamura et al.   MOLECULAR CELL

Maintenance of Silent Chromatin through Replication Requires SWI/SNF-like Chromatin Remodeler SMARCAD1

(2011) Samuel P. Rowbotham et al.   MOLECULAR CELL

Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks

(2011) Lilach Moyal et al.   MOLECULAR CELL

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

(2011) Huadong Pei et al.   NATURE

Condensin association with histone H2A shapes mitotic chromosomes

(2011) Kenji Tada et al.   NATURE

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

(2011) Beat Fierz et al.   Nature Chemical Biology

Centromeres: unique chromatin structures that drive chromosome segregation

(2011) Jolien S. Verdaasdonk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role for hACF1 in the G2/M damage checkpoint

(2011) Sara Sánchez-Molina et al.   NUCLEIC ACIDS RESEARCH

Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors

(2011) H Ogiwara et al.   ONCOGENE

The FUN30 Chromatin Remodeler, Fft3, Protects Centromeric and Subtelomeric Domains from Euchromatin Formation

(2011) Annelie Strålfors et al.   PLoS Genetics

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

Roles of human INO80 chromatin remodeling enzyme in DNA replication and chromosome segregation suppress genome instability

(2010) Shin-Kyoung Hur et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Saccharomyces cerevisiae RAD9, RAD17 and RAD24 genes are required for suppression of mutagenic post-replicative repair during chronic DNA damage

(2010) Akiko Murakami-Sekimata et al.   DNA REPAIR

High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

(2010) Jason S Iacovoni et al.   EMBO JOURNAL

A cooperative activation loop among SWI/SNF, γ-H2AX and H3 acetylation for DNA double-strand break repair

(2010) Han-Sae Lee et al.   EMBO JOURNAL

Loss of H3 K79 Trimethylation Leads to Suppression of Rtt107-dependent DNA Damage Sensitivity through the Translesion Synthesis Pathway

(2010) Nancy Lévesque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

(2010) Ye Xu et al.   JOURNAL OF CELL BIOLOGY

MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair

(2010) G. G. Sharma et al.   MOLECULAR AND CELLULAR BIOLOGY

MOF and H4 K16 Acetylation Play Important Roles in DNA Damage Repair by Modulating Recruitment of DNA Damage Repair Protein Mdc1

(2010) X. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

A Role for Gcn5 in Replication-Coupled Nucleosome Assembly

(2010) Rebecca J. Burgess et al.   MOLECULAR CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes

(2010) Beth A. Helmink et al.   NATURE

Histone variants — ancient wrap artists of the epigenome

(2010) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

(2010) Kyle M Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

(2010) D. M. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Histone Marks Establish the Inner Centromere and Chromosome Bi-Orientation

(2010) Yuya Yamagishi et al.   SCIENCE

Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B

(2010) Alexander E. Kelly et al.   SCIENCE

H3 phosphorylation: dual role in mitosis and interphaseThis paper is one of a selection of papers published in this Special Issue entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference and has undergone the Journal’s usual peer review process.

(2009) Beatriz Pérez-Cadahía et al.   Biochemistry and Cell Biology

Recombinational Repair within Heterochromatin Requires ATP-Dependent Chromatin Remodeling

(2009) Manisha Sinha et al.   CELL

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

Aurora B-Mediated Abscission Checkpoint Protects against Tetraploidization

(2009) Patrick Steigemann et al.   CELL

The checkpoint response to replication stress

(2009) Dana Branzei et al.   DNA REPAIR

INO80-dependent chromatin remodeling regulates early and late stages of mitotic homologous recombination

(2009) Toyoko Tsukuda et al.   DNA REPAIR

HARPing on about the DNA damage response during replication

(2009) R. Driscoll et al.   GENES & DEVELOPMENT

The annealing helicase HARP protects stalled replication forks

(2009) J. Yuan et al.   GENES & DEVELOPMENT

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart

(2009) A. Ciccia et al.   GENES & DEVELOPMENT

The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks

(2009) C. E. Bansbach et al.   GENES & DEVELOPMENT

The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA

(2009) T. Yusufzai et al.   GENES & DEVELOPMENT

Cooperation between the INO80 Complex and Histone Chaperones Determines Adaptation of Stress Gene Transcription in the Yeast Saccharomyces cerevisiae

(2009) E. Klopf et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromosome-wide Rad51 Spreading and SUMO-H2A.Z-Dependent Chromosome Fixation in Response to a Persistent DNA Double-Strand Break

(2009) Marian Kalocsay et al.   MOLECULAR CELL

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

(2009) Peter J. Cook et al.   NATURE

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

(2009) Kok Lung Chan et al.   NATURE CELL BIOLOGY

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

(2009) Susannah L Hewitt et al.   NATURE IMMUNOLOGY

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

(2009) Karina B Falbo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

(2009) Hyun-Soo Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phosphorylation of H2A by Bub1 Prevents Chromosomal Instability Through Localizing Shugoshin

(2009) S. A. Kawashima et al.   SCIENCE

Chromatin dynamics during repair of chromosomal DNA double-strand breaks

(2009) Manisha Sinha et al.   Epigenomics

Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome Assembly

(2008) Qing Li et al.   CELL

Acetylated Lysine 56 on Histone H3 Drives Chromatin Assembly after Repair and Signals for the Completion of Repair

(2008) Chin-Chuan Chen et al.   CELL

Ino80 Chromatin Remodeling Complex Promotes Recovery of Stalled Replication Forks

(2008) Kenji Shimada et al.   CURRENT BIOLOGY

PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint

(2008) Shinichiro Nakada et al.   EMBO REPORTS

Role of Dot1 in the Response to Alkylating DNA Damage in Saccharomyces cerevisiae: Regulation of DNA Damage Tolerance by the Error-Prone Polymerases Pol /Rev1

(2008) F. Conde et al.   GENETICS

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

(2008) Andrew Xiao et al.   NATURE

ATP-dependent chromatin remodeling shapes the DNA replication landscape

(2008) Jack A Vincent et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Ino80 chromatin-remodeling enzyme regulates replisome function and stability

(2008) Manolis Papamichos-Chronakis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HARP Is an ATP-Driven Annealing Helicase

(2008) T. Yusufzai et al.   SCIENCE

Making copies of chromatin: the challenge of nucleosomal organization and epigenetic information

(2008) Armelle Corpet et al.   TRENDS IN CELL BIOLOGY