Article
Surgery
Hisham Hussan, Samuel Akinyeye, Maria Mihaylova, Eric McLaughlin, ChienWei Chiang, Steven K. Clinton, David Lieberman
Summary: Sex differences exist in the associations between obesity and colorectal cancer risk after bariatric surgery. This study found that males have an increased risk of colorectal cancer after bariatric surgery, while females have a decreased risk after Roux-en-Y gastric bypass surgery.
Review
Nutrition & Dietetics
Andrea Chierici, Paolo Amoretti, Celine Drai, Serena De Fatico, Jerome Barriere, Luigi Schiavo, Antonio Iannelli
Summary: A meta-analysis found that bariatric surgery significantly reduces the incidence of colorectal cancer in individuals with obesity, regardless of gender and surgical procedure. Further large-scale studies are needed to confirm these findings.
Article
Surgery
Noam Peleg, Shimon Sapoznikov, Zohar Levi, Iris Dotan, Steven Shamah
Summary: The incidence of colorectal adenomas after bariatric surgery is higher in patients with super morbid obesity (SMO) compared to obese and morbidly obese individuals. Pre-operative BMI should be taken into consideration in the post-operative screening plan for this population.
Article
Oncology
Hisham Hussan, Eric Mclaughlin, Chienwei Chiang, Joseph G. Marsano, David Lieberman
Summary: Obesity is a risk factor for colorectal cancer, and bariatric surgery can mitigate the effect of obesity on the risk of colorectal polyps. However, men still have a higher risk of colorectal cancer compared to women.
Article
Nutrition & Dietetics
Carrie-Anne Lewis, Emma J. Osland, Susan de Jersey, George Hopkins, Matthew Seymour, Lindsey Webb, Mark D. Chatfield, Ingrid J. Hickman
Summary: Bariatric surgery may increase the risk of micronutrient deficiencies. A study in two Australian public hospitals found that preoperative deficiencies were common, and although there was an increase in supplementation after surgery, most nutrients were still below the target dose. Some nutrients had higher deficiency rates after surgery, while others were associated with inflammation or improved glycaemic control.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Gastroenterology & Hepatology
Hisham Hussan, Steven K. Clinton, Elizabeth M. Grainger, Maxine Webb, Cankun Wang, Amy Webb, Bradley Needleman, Sabrena Noria, Jiangjiang Zhu, Fouad Choueiry, Maciej Pietrzak, Michael T. Bailey
Summary: This study suggests that the patterns of gut microbiota may be associated with the risk of colorectal cancer (CRC) after Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) surgeries. Post-surgery patients had higher abundance of sulfide-reducing bacteria and lower abundance of butyrate-producing bacteria compared to pre-surgery subjects.
Article
Multidisciplinary Sciences
Magdalena Taube, Markku Peltonen, Kajsa Sjoeholm, Richard Palmqvist, Johanna C. Andersson-Assarsson, Peter Jacobson, Per-Arne Svensson, Lena M. S. Carlsson
Summary: The impact of bariatric surgery on colorectal cancer risk in obesity patients remains controversial, with conflicting results from studies highlighting the need for more long-term research. In a prospective study, bariatric surgery was not found to be associated with altered risk of colorectal cancer.
Article
Surgery
Joonas H. Kauppila, Giola Santoni, Wenjing Tao, Elsebeth Lynge, Jussi Jokinen, Laufey Tryggvadottir, Eivind Ness-Jensen, Eero Pukkala, My Von Euler-Chelpin, Jesper Lagergren
Summary: This study identified risk factors for suicide after bariatric surgery, including gender, surgery type, and psychiatric disorders. Female patients had a lower risk of suicide compared to males, while gastric bypass surgery had a lower risk compared to other types of bariatric surgery. Patients with a history of depression or anxiety, mania, bipolar disorder, psychosis, schizophrenia, or substance use were at an increased risk of suicide.
Article
Surgery
Omar Suhail Alsaed, Abdul-Wahab Al-Allaf, Isra Elgenaied, Rawand Abdelnaser Jebril, Sreethish Sasi, Ashraf Omer Ahmed, Rabab Boussarsar, Mohamed Izham Mohamed Ibrahim, Ibrahim Abdulmomen, Wahiba Elhag, Samar A. Al Razaq Alemadi
Summary: The study indicates that patients who undergo bariatric surgery have a higher risk of fractures, mainly affecting the feet and hands, and fractures tend to occur earlier compared to controls.
Article
Nutrition & Dietetics
Zainab Akhter, Nicola Heslehurst, Dries Ceulemans, Judith Rankin, Roger Ackroyd, Roland Devlieger
Summary: Prior bariatric surgery is a significant risk factor for delivering small for gestational age (SGA) babies, with factors such as gestational weight gain, receiving nutritional advice, and weight management playing significant roles in influencing the risk of SGA babies.
Article
Surgery
Shao Nan Khor, S. H. X. Cheok, Rehena Sultana, Emile Kwong Wei Tan
Summary: This study compares the incidence of incisional hernias between laparoscopic and open surgery, and identifies risk factors associated with incisional hernias among Asian patients who have undergone major resection for colorectal cancer. The results show that there is no significant difference in the incidence of incisional hernias between laparoscopic and open surgery in Asian patients.
ASIAN JOURNAL OF SURGERY
(2023)
Review
Oncology
Edward R. Sauter, Brandy Heckman-Stoddard
Summary: Metabolic (bariatric) surgery provides significant weight loss and improvement in type 2 diabetes mellitus and cardiovascular risk in morbidly obese individuals. There is emerging evidence that MBS may also impact cancer risk, although the specific factors influencing this and the underlying mechanisms are still unclear.
Review
Surgery
Sara D'Amato, Maria Sofia, Marcello Agosta, Giorgia Litrico, Iacopo Sarva, Gaetano La Greca, Saverio Latteri
Summary: Obesity is a risk factor for different types of cancer. Bariatric surgery can reduce cancer risk, but its impact on colorectal cancer risk is controversial. Changes in gut microbiota and bile acid concentrations caused by bariatric surgery may increase the risk of colorectal cancer.
SURGERY FOR OBESITY AND RELATED DISEASES
(2023)
Review
Medicine, General & Internal
Roberta Maselli, Matteo Fiacca, Gaia Pellegatta, Roberto de Sire, Federico De Blasio, Antonio Capogreco, Piera Alessia Galtieri, Davide Massimi, Manuela Trotta, Cesare Hassan, Alessandro Repici
Summary: This article investigates the potential connection between bariatric surgery and the subsequent occurrence of achalasia. The study finds that peroral endoscopic myotomy (POEM) is a technically viable and safe intervention for achalasia in the bariatric surgery population.
Article
Obstetrics & Gynecology
E. Nilsson-Condori, K. Mattsson, A. Thurin-Kjellberg, J. L. Hedenbro, B. Friberg
Summary: Previous bariatric surgery does not significantly affect the cumulative live birth rate in IVF, despite a lower number of retrieved oocytes and frozen embryos in the surgery group, as well as a lower birth weight in children born to mothers with previous surgery.
HUMAN REPRODUCTION
(2022)
Article
Gastroenterology & Hepatology
Mark Lawler, Deborah Alsina, Richard A. Adams, Annie S. Anderson, Gina Brown, Nicola S. Fearnhead, Stephen W. Fenwick, Stephen P. Halloran, Daniel Hochhauser, Mark A. Hull, Viktor H. Koelzer, Angus G. K. McNair, Kevin J. Monahan, Inke Nathke, Christine Norton, Marco R. Novelli, Robert J. C. Steele, Anne L. Thomas, Lisa M. Wilde, Richard H. Wilson, Ian Tomlinson
Article
Gastroenterology & Hepatology
Nicholas E. Burr, Chris Smith, Robert West, Mark A. Hull, Venkataraman Subramanian
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2018)
Article
Nutrition & Dietetics
Mark A. Hull
Summary: Preventability estimate for colorectal cancer (CRC) is approximately 50%, with evidence that dietary factors affect CRC risk, though limited public health impact. Chemoprevention using supplements may provide an effective approach.
PROCEEDINGS OF THE NUTRITION SOCIETY
(2021)
Letter
Gastroenterology & Hepatology
Andrea C. Masi, Sara Koo, Christopher A. Lamb, Mark A. Hull, Linda Sharp, Andrew Nelson, James S. Hampton, Colin J. Rees, Christopher J. Stewart
Article
Gastroenterology & Hepatology
Mark A. Hull, Colin J. Rees, Linda Sharp, Sara Koo
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
(2020)
Article
Gastroenterology & Hepatology
Joanna Aldoori, Andrew J. Cockbain, Giles J. Toogood, Mark A. Hull
Summary: Experimental studies have shown that marine omega-3 polyunsaturated fatty acids have anti-inflammatory and anticancer properties. Clinical data suggest that the activity of O3FAs in colorectal cancer depends on host and tumor characteristics, and further investigation is needed on the effect of O3FAs on gut microbiota for optimal prevention and treatment of CRC.
Article
Genetics & Heredity
Rachel Moon, J. Bernadette Moore, Mark A. Hull, Michael A. Zulyniak
Summary: Blood levels of ARA do not associate with colorectal polyp incidence in a general healthy population.
LIFESTYLE GENOMICS
(2022)
Article
Gastroenterology & Hepatology
Amy Downing, Hayley Fenton, Claire Nickerson, Paul M. Loadman, Elizabeth A. Williams, Colin J. Rees, Louise C. Brown, Eva J. A. Morris, Mark A. Hull
Summary: This study investigates the risk of colorectal polyps after short-term aspirin use. The results show that individuals who received aspirin demonstrated increased colorectal polyp risk during post-trial surveillance. This has important implications for aspirin cessation driven by age-related bleeding risk.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Oncology
Ge Sun, Harriett Fuller, Hayley Fenton, Amanda D. Race, Amy Downing, Elizabeth A. Williams, Colin J. Rees, Louise C. Brown, Paul M. Loadman, Mark A. Hull
Summary: Urinary levels of PGE-M and 11-d-TXB2 are reduced by aspirin and EPA, and high levels of 11-d-TXB2 predict increased risk of colorectal polyps.
INTERNATIONAL JOURNAL OF CANCER
(2023)
