Article
Surgery
Vijaya T. Daniel, Karim Alavi, Jennifer S. Davids, Cristina R. Harnsberger, Justin A. Maykel
Summary: The study survey revealed a lack of consensus on the definition of anastomotic leaks, indicating the urgent need for standardization to impact outcomes measurement, research trials, and healthcare reimbursement.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Surgery
Medhat Aker, Alan Askari, Mohamed Rabie, Mohamed Aly, Samuel Adegbola, Krashna Patel, Chelise Currow, Rebecca Nunn, Christopher Hadjittofi, Adeline Rankin, Sonal Halai, Karim Elsamani, Sophie Bondje, Islam Mohamed, John Lee, Joshua Wong, Eve Robertson-Waters, Aaliya Uddin, James Hollingshead
Summary: This multi-centre study explored different management strategies for colorectal anastomotic leaks (AL), including conservative treatment, radiological drainage, and surgery. The findings suggest that conservative management can lead to shorter length of hospital stay, and patients with a defunctioning stoma are more likely to have successful conservative treatment. Although the majority of AL patients can be successfully managed conservatively, approximately two out of five patients still require surgery intervention.
INTERNATIONAL JOURNAL OF SURGERY
(2021)
Article
Medicine, General & Internal
Eugenia Claudia Zarnescu, Narcis Octavian Zarnescu, Radu Costea
Summary: Anastomotic leakage is a severe complication following colorectal surgery, with multiple risk factors identified. There are both nonmodifiable and modifiable risk factors associated with this complication. Different preoperative and postoperative approaches may not necessarily reduce the occurrence of anastomotic leakage.
Article
Surgery
Maxime Laydi, Alexandre Doussot, Zaher Lakkis, Pierre Mathieu, Anne Gandon, Louis Martin, Bruno Heyd, Guillaume Piessen
Summary: The presentation of anastomotic leakage after Ivor Lewis esophagectomy can vary on imaging, and these anatomical patterns may influence the management and outcomes of the leakage.
Article
Oncology
Liliana Mereu, Francesca Dalpra, Valeria Berlanda, Riccardo Pertile, Daniela Coser, Basilio Pecorino, Maria Gabriella D'Agate, Francesco Ciarleglio, Alberto Brolese, Saverio Tateo
Summary: This study evaluated the incidence, risk factors, and utility of drainage and stoma in patients undergoing intestinal surgery for ovarian cancer. The results showed that rectosigmoid resection for ovarian cancer is a standardized procedure with comparable results for anastomotic leakage (AL), and risk factors for AL are discretely homogeneous. The use of stomas and/or drains, however, was not standardized according to the literature. Therefore, further exploration is needed to verify the preventive role of protective stoma and/or intra-abdominal drains in selected and standardized situations.
Article
Surgery
Jae-Woo Ju, Ho-Jin Lee, Min Jung Kim, Seung-Bum Ryoo, Won Ho Kim, Seung-Yong Jeong, Kyu Joo Park, Ji Won Park
Summary: This study aimed to investigate the association between early postoperative NSAID use and anastomotic leakage (AL) in patients who underwent colorectal cancer surgery. The findings showed a significant association between early postoperative NSAID use and AL.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Surgery
Willem A. Bemelman, Alberto Arezzo, Tomasz Banasiewicz, Richard Brady, Eloy Espin-Basany, Omar Faiz, Rosa M. Jimenez-Rodriguez
Summary: This study aimed to establish a consensus on the optimal use of sponge-assisted endoluminal vacuum therapy (EVT) for the management of anastomotic leaks. Through a series of discussions, the expert group formulated 37 recommendations and statements, answering key questions regarding the indications and benefits of sponge-assisted EVT.
Review
Oncology
S. L. Kastora, L. L. Osborne, R. Jardine, G. Kounidas, B. Carter, P. K. Myint
Summary: This study aimed to assess the impact of NSAIDs on anastomotic leak in colorectal cancer patients and found that colocolic anastomoses were more prone to leaks. Male gender was identified as an independent confounder increasing the rate of leaks.
Article
Surgery
Lukas F. Liesenfeld, Thomas Schmidt, Christine Zhang-Hagenlocher, Peter Sauer, Markus K. Diener, Beat P. Mueller-Stich, Thilo Hackert, Markus W. Buechler, Anja Schaible
Summary: The study retrospectively analyzed patients with AL after UGI cancer surgery, confirming that SEMS is a safe and effective tool for treating AL, with treatment success rates correlated with stent length and width. It is strongly recommended to switch to alternative treatments if signs of persistent leakage are present beyond 72 hours after stent placement.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Gastroenterology & Hepatology
Li Wang, Zu-Qiang Liu, Jing-Zheng Liu, Li-Yun Ma, Xiao-Qing Li, Lu Yao, Quan-Lin Li, Ping-Hong Zhou
Summary: ESD is a safe and effective treatment for anastomotic lesions of the lower gastrointestinal tract, with favorable short-term and long-term outcomes.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Surgery
Andres R. Latorre-Rodriguez, Jasmine Huang, Lara Schaheen, Michael A. Smith, Samad Hashimi, Ross M. Bremner, Sumeet K. Mittal
Summary: The purpose of this study was to assess the incidence, diagnostic approach, and management of esophageal anastomotic leaks (ALs) after Ivor Lewis esophagectomy. The study included 145 patients who underwent the surgery from August 2016 to July 2022. Out of these, 10 patients (6.9%) developed an AL, which was diagnosed using various methods such as enteric contents in wound drains, endoscopy, CT, and contrast esophagogram.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
Article
Surgery
Richard T. Spence, Dhruvin H. Hirpara, Sachin Doshi, Fayez A. Quereshy, Sami A. Chadi
Summary: A study found that early anastomotic leaks (within three days post-surgery) were associated with a higher failure to rescue rate. Therefore, early detection algorithms and interventions are recommended to minimize the risk of failure to rescue.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Gastroenterology & Hepatology
Nicola Reeves, Irene Vogel, Arash Ghoroghi, James Ansell, Julie Cornish, Jared Torkington
Summary: This study assessed the applicability of peritoneal cytokine levels as an early predictive test of Anastomotic Leakage (AL) in postoperative colorectal cancer patients. The meta-analysis found that IL-10 was significantly raised in AL patients on postoperative day 1, suggesting its potential as an early predictor for AL in this patient population. More research is needed due to the limited range of cytokines studied and the heterogeneous nature of the existing studies.
TECHNIQUES IN COLOPROCTOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Irmina A. Elliott, Mark F. Berry, Winston Trope, Natalie S. Lui, Brandon A. Guenthart, Douglas Z. Liou, Richard I. Whyte, Leah M. Backhus, Joseph B. Shrager
Summary: This study demonstrates that the sensitivity of fluoroscopic esophagography with oral administration of contrast material to exclude anastomotic leak after esophagectomy is not well established, and the consequences of missing a leak in this setting have not been previously described. Therefore, a high index of suspicion must be maintained even after a normal esophagram result, and the common practice of using this test to triage patients for diet advancement is questioned.
ANNALS OF THORACIC SURGERY
(2023)
Article
Surgery
Massimo Carlini, Michele Grieco, Domenico Spoletini, Rosa Menditto, Vincenzo Napoleone, Gioia Brachini, Andrea Mingoli, Rosa Marcellinaro
Summary: This pilot study evaluated a novel perioperative treatment for patients undergoing laparoscopic colorectal resections for cancer. The results showed that the treatment significantly reduced the incidence of anastomotic leaks and led to shorter postoperative recovery and hospital stay.
UPDATES IN SURGERY
(2022)
