First-line therapy in adult Crohn's disease: who should receive anti-TNF agents?

943c ACCELERATED STEP-CARE THERAPY WITH EARLY AZATHIOPRINE (AZA) VS. CONVENTIONAL STEP-CARE THERAPY IN CROHN'S DISEASE. A RANDOMIZED STUDY.

(2015) J. Cosnes et al.   GASTROENTEROLOGY

A systematic review and economic evaluation of the use of tumour necrosis factor-alpha (TNF-α) inhibitors, adalimumab and infliximab, for Crohn’s disease

(2014) J Dretzke et al.   HEALTH TECHNOLOGY ASSESSMENT

Clinical Risk Factors for Complicated Disease: How Reliable Are They?

(2013) Camille Zallot et al.   DIGESTIVE DISEASES

Review article: the natural history of postoperative Crohn's disease recurrence

(2012) A. Buisson et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

A Pooled Analysis of Infections, Malignancy and Mortality in Infliximab- and Immunomodulator-Treated Adult Patients With Inflammatory Bowel Disease

(2012) Gary R Lichtenstein et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

T-Cell Non-Hodgkin's Lymphomas Reported to the FDA AERS With Tumor Necrosis Factor-Alpha (TNF-α) Inhibitors: Results of the REFURBISH Study

(2012) Parakkal Deepak et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Development of the Paris Definition of Early Crohn's Disease for Disease-Modification Trials: Results of an International Expert Opinion Process

(2012) Laurent Peyrin-Biroulet et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Diagnosis, prevention and treatment of postoperative Crohn's disease recurrence

(2012) Anthony Buisson et al.   DIGESTIVE AND LIVER DISEASE

Immunosuppression-Related Lymphomas and Cancers in IBD: How Can They Be Prevented?

(2012) Laurent Beaugerie   DIGESTIVE DISEASES

Adalimumab Induces and Maintains Mucosal Healing in Patients With Crohn's Disease: Data From the EXTEND Trial

(2012) Paul Rutgeerts et al.   GASTROENTEROLOGY

Mucosal healing—EXTENDing our knowledge in Crohn's disease

(2012) Silvio Danese et al.   Nature Reviews Gastroenterology & Hepatology

Increased Risk for Nonmelanoma Skin Cancers in Patients Who Receive Thiopurines for Inflammatory Bowel Disease

(2011) Laurent Peyrin–Biroulet et al.   GASTROENTEROLOGY

Development of the first disability index for inflammatory bowel disease based on the international classification of functioning, disability and health

(2011) Laurent Peyrin-Biroulet et al.   GUT

Surgery for adult Crohn's disease: what is the actual risk?

(2011) G. Bouguen et al.   GUT

Early use of immunosuppressives or TNF antagonists for the treatment of Crohn's disease: time for a change

(2011) I. Ordas et al.   GUT

Impact of azathioprine and tumour necrosis factor antagonists on the need for surgery in newly diagnosed Crohn's disease

(2011) L. Peyrin-Biroulet et al.   GUT

Results from the 2nd Scientific Workshop of the ECCO (I): Impact of mucosal healing on the course of inflammatory bowel disease

(2011) Laurent Peyrin-Biroulet et al.   Journal of Crohns & Colitis

Canadian cost-utility analysis of initiation and maintenance treatment with anti-TNF-α drugs for refractory Crohn's disease

(2011) Gord Blackhouse et al.   Journal of Crohns & Colitis

Costs of care for Crohn’s disease following the introduction of infliximab: a single-centre UK experience

(2010) M. B. Sprakes et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Frequency and Risk Factors for Extraintestinal Manifestations in the Swiss Inflammatory Bowel Disease Cohort

(2010) Stephan R Vavricka et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Increased Response and Remission Rates in Short-Duration Crohn's Disease With Subcutaneous Certolizumab Pegol: An Analysis of PRECiSE 2 Randomized Maintenance Trial Data

(2010) Stefan Schreiber et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Advanced Age Is an Independent Risk Factor for Severe Infections and Mortality in Patients Given Anti–Tumor Necrosis Factor Therapy for Inflammatory Bowel Disease

(2010) Mario Cottone et al.   Clinical Gastroenterology and Hepatology

A Systematic Review of Factors That Contribute to Hepatosplenic T-Cell Lymphoma in Patients With Inflammatory Bowel Disease

(2010) David S. Kotlyar et al.   Clinical Gastroenterology and Hepatology

Risk Factors Associated With Progression to Intestinal Complications of Crohn's Disease in a Population-Based Cohort

(2010) Kelvin T. Thia et al.   GASTROENTEROLOGY

Early Crohn disease: a proposed definition for use in disease-modification trials

(2010) L. Peyrin-Biroulet et al.   GUT

Optimizing thiopurine therapy in inflammatory bowel disease

(2010) Jean-Baptiste Chevaux et al.   INFLAMMATORY BOWEL DISEASES

Development of the Crohnʼs disease digestive damage score, the Lémann score

(2010) Benjamin Pariente et al.   INFLAMMATORY BOWEL DISEASES

Long-term complications, extraintestinal manifestations, and mortality in adult Crohnʼs disease in population-based cohorts

(2010) Laurent Peyrin-Biroulet et al.   INFLAMMATORY BOWEL DISEASES

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management

(2010) A. Dignass et al.   Journal of Crohns & Colitis

Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease

(2010) Jean Frédéric Colombel et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Natural History of Adult Crohn's Disease in Population-Based Cohorts

(2009) Laurent Peyrin-Biroulet et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Management of Crohn's Disease in Adults

(2009) Gary R Lichtenstein et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Risk of Lymphoma Associated With Combination Anti–Tumor Necrosis Factor and Immunomodulator Therapy for the Treatment of Crohn's Disease: A Meta-Analysis

(2009) Corey A. Siegel et al.   Clinical Gastroenterology and Hepatology

Adalimumab for the treatment of fistulas in patients with Crohn's disease

(2009) J-F Colombel et al.   GUT

Adalimumab safety in global clinical trials of patients with Crohnʼs disease

(2009) Jean-Frédéric Colombel et al.   INFLAMMATORY BOWEL DISEASES

Disability in inflammatory bowel diseases: Developing ICF core sets for patients with inflammatory bowel diseases based on the international classification of functioning, disability, and health

(2009) Laurent Peyrin-Biroulet et al.   INFLAMMATORY BOWEL DISEASES

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations

(2009) Gert Van Assche et al.   Journal of Crohns & Colitis

Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study

(2009) Laurent Beaugerie et al.   LANCET

Clinical implications of mucosal healing for the management of IBD

(2009) Guillaume Pineton de Chambrun et al.   Nature Reviews Gastroenterology & Hepatology

Efficacy and Safety of Tumor Necrosis Factor Antagonists in Crohn's Disease: Meta-Analysis of Placebo-Controlled Trials

(2008) Laurent Peyrin–Biroulet et al.   Clinical Gastroenterology and Hepatology

Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort study

(2008) H Fidder et al.   GUT

Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial

(2008) Geert D'Haens et al.   LANCET

Are we giving azathioprine too late? The case for early immunomodulation in inflammatory bowel disease

(2008) María Josefina Etchevers et al.   WORLD JOURNAL OF GASTROENTEROLOGY