Autophagy: a new target or an old strategy for the treatment of Crohn's disease?
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Autophagy: a new target or an old strategy for the treatment of Crohn's disease?
Authors
Keywords
-
Journal
Nature Reviews Gastroenterology & Hepatology
Volume 10, Issue 7, Pages 395-401
Publisher
Springer Nature
Online
2013-04-16
DOI
10.1038/nrgastro.2013.66
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- P668 ATG16L1 genotype is associated with response to anti-TNF in vitro
- (2013) M. Wildenberg et al. Journal of Crohns & Colitis
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- mTOR and metabolic pathways in T cell quiescence and functional activation
- (2013) Kai Yang et al. SEMINARS IN IMMUNOLOGY
- Autophagy and the Immune System
- (2012) Petric Kuballa et al. Annual Review of Immunology
- Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage
- (2012) Jing Han et al. Autophagy
- Autophagy in tumorigenesis and cancer therapy: Dr. Jekyll or Mr. Hyde?
- (2012) Shengtao Zhou et al. CANCER LETTERS
- Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway
- (2012) Robert O. Watson et al. CELL
- Is the Autophagy Induced by Thiopurines Beneficial or Deleterious?
- (2012) Luis G. Guijarro et al. CURRENT DRUG METABOLISM
- Pharmacological Control of Autophagy: Therapeutic Perspectives in Inflammatory Bowel Disease and Colorectal Cancer
- (2012) Sofia Garcia-Maurino et al. CURRENT PHARMACEUTICAL DESIGN
- Curcumin and Inflammatory Bowel Disease: Biological Mechanisms and Clinical Implication
- (2012) Tauseef Ali et al. DIGESTION
- New Drug Therapies on the Horizon for IBD
- (2012) Clémentine Perrier et al. DIGESTIVE DISEASES
- Towards a Novel Molecular Classification of IBD
- (2012) Severine Vermeire DIGESTIVE DISEASES
- Second-Generation Corticosteroids for the Treatment of Crohns Disease and Ulcerative Colitis: More Effective and Less Side Effects?
- (2012) Chiara De Cassan et al. DIGESTIVE DISEASES
- Intestinal Epithelial Cells with Impaired Autophagy Lose Their Adhesive Capacity in the Presence of TNF-α
- (2012) Masaya Saito et al. DIGESTIVE DISEASES AND SCIENCES
- Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury
- (2012) Shunsaku Nakagawa et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Autophagy Attenuates the Adaptive Immune Response by Destabilizing the Immunologic Synapse
- (2012) Manon E. Wildenberg et al. GASTROENTEROLOGY
- The contribution of autophagy to lymphocyte survival and homeostasis
- (2012) Ian X. McLeod et al. IMMUNOLOGICAL REVIEWS
- Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion
- (2012) Teresa L. M. Thurston et al. NATURE
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Regulation of inflammasome signaling
- (2012) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
- (2012) Chong-Shan Shi et al. NATURE IMMUNOLOGY
- Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
- (2012) E. F. Castillo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis
- (2012) I. D. Iliev et al. SCIENCE
- TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts
- (2012) Alison M Connor et al. ARTHRITIS RESEARCH & THERAPY
- Paradoxical Aspects of Rapamycin Immunobiology in Transplantation
- (2011) I. R. Ferrer et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- SNP-guided microRNA maps (MirMaps) of 16 common human disorders identify a clinically accessible therapy reversing transcriptional aberrations of nuclear import and inflammasome pathways
- (2011) Gennadi V. Glinsky CELL CYCLE
- Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors
- (2011) Vojo Deretic CURRENT OPINION IN IMMUNOLOGY
- Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
- (2011) Nicolas Dupont et al. EMBO JOURNAL
- Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2
- (2011) T. S. Plantinga et al. GUT
- Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
- (2011) James Harris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan
- (2011) Silvestre Alavez et al. NATURE
- Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
- (2011) M. Michaud et al. SCIENCE
- A Family of IFN- -Inducible 65-kD GTPases Protects Against Bacterial Infection
- (2011) B.-H. Kim et al. SCIENCE
- Management of Inflammatory Bowel Disease with Infliximab and Other Anti-Tumor Necrosis Factor Alpha Therapies
- (2010) Fernando Magro et al. BIODRUGS
- Autophagy Protects against Sindbis Virus Infection of the Central Nervous System
- (2010) Anthony Orvedahl et al. Cell Host & Microbe
- Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties
- (2010) Marisa Ponpuak et al. IMMUNITY
- Genetic variation in the autophagy gene ULK1 and risk of Crohnʼs disease
- (2010) Liesbet Henckaerts et al. INFLAMMATORY BOWEL DISEASES
- Use of complementary and alternative medicine by patients with inflammatory bowel disease
- (2010) Robert J. Hilsden et al. INFLAMMATORY BOWEL DISEASES
- TNF-α Induces Macroautophagy and Regulates MHC Class II Expression in Human Skeletal Muscle Cells
- (2010) Christian W. Keller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Unconventional secretion ofPichia pastorisAcb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation
- (2010) Ravi Manjithaya et al. JOURNAL OF CELL BIOLOGY
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
- (2010) Andre Franke et al. NATURE GENETICS
- The potential for disease modification in Crohn's disease
- (2010) G. Van Assche et al. Nature Reviews Gastroenterology & Hepatology
- Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease
- (2010) Jean Frédéric Colombel et al. NEW ENGLAND JOURNAL OF MEDICINE
- The genetics of inflammatory bowel disease: diagnostic and therapeutic implications
- (2010) Carmen Cuffari World Journal of Pediatrics
- Effect of Cyclodextrin Complexation of Curcumin on its Solubility and Antiangiogenic and Anti-inflammatory Activity in Rat Colitis Model
- (2009) Vivek R. Yadav et al. AAPS PHARMSCITECH
- Shigella Phagocytic Vacuolar Membrane Remnants Participate in the Cellular Response to Pathogen Invasion and Are Regulated by Autophagy
- (2009) Nicolas Dupont et al. Cell Host & Microbe
- Chloroquine and its analogs: A new promise of an old drug for effective and safe cancer therapies
- (2009) V. Raja Solomon et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Biological Therapies for Inflammatory Bowel Diseases
- (2009) Paul Rutgeerts et al. GASTROENTEROLOGY
- Listeria monocytogenes ActA-mediated escape from autophagic recognition
- (2009) Yuko Yoshikawa et al. NATURE CELL BIOLOGY
- Genetic Association Analysis of the Functional c.714T>G Polymorphism and Mucosal Expression of Dectin-1 in Inflammatory Bowel Disease
- (2009) Hilbert S. de Vries et al. PLoS One
- Using genetic information for the identification, classification and treatment of Crohn’s disease: are we there yet?
- (2009) Rinse K Weersma et al. Expert Review of Gastroenterology & Hepatology
- A Multicenter, Randomized, Double-Blind Trial of EverolimusVersusAzathioprine and Placebo to Maintain Steroid-Induced Remission in Patients With Moderate-to-Severe Active Crohn's Disease
- (2008) Walter Reinisch et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Toll-like receptors control autophagy
- (2008) Mónica A Delgado et al. EMBO JOURNAL
- Use of sirolimus (rapamycin) to treat refractory Crohn's disease
- (2008) D C O Massey et al. GUT
- Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
- (2008) Bharat B. Aggarwal et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages
- (2008) Chong-Shan Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
- Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
- (2008) Jelena Nedjic et al. NATURE
- Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
- (2008) Tatsuya Saitoh et al. NATURE
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
- Thiopurine S-methyltransferase pharmacogenetics: autophagy as a mechanism for variant allozyme degradation
- (2008) Fang Li et al. Pharmacogenetics and Genomics
- Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study
- (2007) G A W Bruyn et al. ANNALS OF THE RHEUMATIC DISEASES
- Plasmodium falciparum: Erythrocytic stages die by autophagic-like cell death under drug pressure
- (2007) Paulo Renato Rivas Totino et al. EXPERIMENTAL PARASITOLOGY
- Differential toxic effects of azathioprine, 6-mercaptopurine and 6-thioguanine on human hepatocytes
- (2007) Elise Petit et al. TOXICOLOGY IN VITRO
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More