The molecular and cellular heterogeneity of pancreatic ductal adenocarcinoma

An Effective Personalized Approach to a Rare Tumor: Prolonged Survival in Metastatic Pancreatic Acinar Cell Carcinoma Based on Genetic Analysis and Cell Line Development

(2012) Matthew D. Armstrong et al.   Journal of Cancer

Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin

(2011) S Rachagani et al.   BRITISH JOURNAL OF CANCER

Pancreatic Ductal Adenocarcinoma Mice Lacking Mucin 1 Have a Profound Defect in Tumor Growth and Metastasis

(2011) D. M. Besmer et al.   CANCER RESEARCH

Genome-Wide Analysis of Promoter Methylation Associated with Gene Expression Profile in Pancreatic Adenocarcinoma

(2011) A. Vincent et al.   CLINICAL CANCER RESEARCH

Somatic variation and cancer: therapies lost in the mix

(2011) Andrew V. Biankin et al.   HUMAN GENETICS

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

(2011) Ignacio Varela et al.   NATURE

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

(2011) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

GATA6 Activates Wnt Signaling in Pancreatic Cancer by Negatively Regulating the Wnt Antagonist Dickkopf-1

(2011) Yi Zhong et al.   PLoS One

Exploring the Genomes of Cancer Cells: Progress and Promise

(2011) M. R. Stratton   SCIENCE

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Frequent genomic copy number gain and overexpression of GATA-6 in pancreatic carcinoma

(2010) Baojin Fu et al.   CANCER BIOLOGY & THERAPY

A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells

(2010) Oliver A. Kent et al.   CANCER BIOLOGY & THERAPY

Stromal biology and therapy in pancreatic cancer

(2010) A. Neesse et al.   GUT

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

(2010) M. C. Villarroel et al.   MOLECULAR CANCER THERAPEUTICS

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

(2010) Peter J. Campbell et al.   NATURE

International network of cancer genome projects

(2010) Thomas J. Hudson (Chairperson) et al.   NATURE

The molecular pathology of cancer

(2010) Timothy J. R. Harris et al.   Nature Reviews Clinical Oncology

Pancreatic cancer: understanding and overcoming chemoresistance

(2010) Zhiwei Wang et al.   Nature Reviews Gastroenterology & Hepatology

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway

(2009) Z. Wang et al.   CANCER RESEARCH

Linking somatic genetic alterations in cancer to therapeutics

(2009) Darrin Stuart et al.   CURRENT OPINION IN CELL BIOLOGY

CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells

(2009) Sung Pil Hong et al.   INTERNATIONAL JOURNAL OF CANCER

DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer

(2009) Christine A. Iacobuzio-Donahue et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular predictors of response to trastuzumab and lapatinib in breast cancer

(2009) Francisco J. Esteva et al.   Nature Reviews Clinical Oncology

Pancreatic cancer: molecular pathogenesis and new therapeutic targets

(2009) Han H. Wong et al.   Nature Reviews Gastroenterology & Hepatology

Proteomics of Pancreatic Cancer

(2009) Ilona Gräntzdörffer et al.   PANCREAS

Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

(2009) S. Jones et al.   SCIENCE

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Pancreatic Cancer

(2008) Anirban Maitra et al.   Annual Review of Pathology-Mechanisms of Disease

Hoxb7 Inhibits Transgenic HER-2/neu-Induced Mouse Mammary Tumor Onset but Promotes Progression and Lung Metastasis

(2008) H. Chen et al.   CANCER RESEARCH

Identification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridization

(2008) Ayako Suzuki et al.   CANCER SCIENCE

MicroRNA-21 is Overexpressed in Pancreatic Cancer and a Potential Predictor of Survival

(2008) Mary Dillhoff et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Molecular Genetics of Pancreatic Ductal Adenocarcinomas and Recent Implications for Translational Efforts

(2008) Georg Feldmann et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Genome-Wide Analysis of Pancreatic Cancer Using Microarray-Based Techniques

(2008) Tomohiko Harada et al.   PANCREATOLOGY

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis

(2008) Yuqing Zhang et al.   WORLD JOURNAL OF SURGERY