Paradigm shifts in thyroid hormone replacement therapies for hypothyroidism

Combined therapy with L-Thyroxine and L-Triiodothyronine compared to L-Thyroxine alone in the treatment of primary hypothyroidism

(2014) Valentine Fadeyev et al.   Hormones-International Journal of Endocrinology and Metabolism

Clinical practice guidelines for the management of hypothyroidism

(2013) Gabriela Brenta et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Patient-reported outcomes in adequately treated hypothyroidism – insights from the German versions of ThyDQoL, ThySRQ and ThyTSQ

(2013) Eva M Quinque et al.   Health and Quality of Life Outcomes

The Dynamic Pituitary Response to Escalating-Dose TRH Stimulation Test in Hypothyroid Patients Treated With Liothyronine or Levothyroxine Replacement Therapy

(2013) Sahzene Yavuz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Desiccated Thyroid Extract Compared With Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-Blind, Crossover Study

(2013) Thanh D. Hoang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Peripheral markers of thyroid function: the effect of T4 monotherapy vs T4/T3 combination therapy in hypothyroid subjects in a randomized crossover study

(2013) Ulla Schmidt et al.   Endocrine Connections

TSH-suppressive doses of levothyroxine are required to achieve preoperative native serum triiodothyronine levels in patients who have undergone total thyroidectomy

(2012) Mitsuru Ito et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Fatigue and fatigue-related symptoms in patients treated for different causes of hypothyroidism

(2012) Marloes Louwerens et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Is pituitary TSH an adequate measure of thyroid hormone-controlled homoeostasis during thyroxine treatment?

(2012) Rudolf Hoermann et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Combination Treatment with T4and T3: Toward Personalized Replacement Therapy in Hypothyroidism?

(2012) Bernadette Biondi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Generation of functional thyroid from embryonic stem cells

(2012) Francesco Antonica et al.   NATURE

Clinical Practice Guidelines for Hypothyroidism in Adults: Cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association

(2012) Jeffrey R. Garber et al.   THYROID

A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement

(2011) Peter N Taylor et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels

(2011) Marco Medici et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Metabolic Effects of Liothyronine Therapy in Hypothyroidism: A Randomized, Double-Blind, Crossover Trial of LiothyronineVersusLevothyroxine

(2011) Francesco S. Celi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients

(2011) Damiano Gullo et al.   PLoS One

Prevalence and Relative Risk of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease

(2010) Kristien Boelaert et al.   AMERICAN JOURNAL OF MEDICINE

The pharmacodynamic equivalence of levothyroxine and liothyronine: a randomized, double blind, cross-over study in thyroidectomized patients

(2010) Francesco S. Celi et al.   CLINICAL ENDOCRINOLOGY

Diseases associated with thyroid autoimmunity: explanations for the expanding spectrum

(2010) A. P. Weetman   CLINICAL ENDOCRINOLOGY

Hashimoto's Thyroiditis Affects Symptom Load and Quality of Life Unrelated to Hypothyroidism: A Prospective Case–Control Study in Women Undergoing Thyroidectomy for Benign Goiter

(2010) Johannes Ott et al.   THYROID

Are Individuals With an Autoimmune Disease at Higher Risk of a Second Autoimmune Disorder?

(2009) E. C. Somers et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Trends in thyroid hormone prescribing and consumption in the UK

(2009) Anna L Mitchell et al.   BMC PUBLIC HEALTH

A paradoxical difference in relationship between anxiety, depression and thyroid function in subjects on and not on T4: findings from the HUNT study

(2009) Vijay Panicker et al.   CLINICAL ENDOCRINOLOGY

Effect of combination therapy with thyroxine (T4) and 3,5,3′-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study

(2009) Birte Nygaard et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Do we need still more trials on T4 and T3 combination therapy in hypothyroidism?

(2009) Wilmar M Wiersinga   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Phosphodiesterase 8B Gene Polymorphism Is Associated with Subclinical Hypothyroidism in Pregnancy

(2009) Beverley M. Shields et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Common Variation in theDIO2Gene Predicts Baseline Psychological Well-Being and Response to Combination Thyroxine Plus Triiodothyronine Therapy in Hypothyroid Patients

(2009) Vijay Panicker et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

For Some,l-Thyroxine Replacement Might Not Be Enough: A Genetic Rationale

(2009) Brian W. Kim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Serum Thyroid-Stimulating Hormone Concentration and Morbidity from Cardiovascular Disease and Fractures in Patients on Long-Term Thyroxine Therapy

(2009) Robert W. Flynn et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Novel insights into thyroid hormones from the study of common genetic variation

(2009) Colin M. Dayan et al.   Nature Reviews Endocrinology

Thyroxine alone or thyroxine plus triiodothyronine replacement therapy for hypothyroidism

(2009) Ma Chao et al.   NUCLEAR MEDICINE COMMUNICATIONS

Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function

(2008) Lisette Arnaud-Lopez et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polymorphisms in the brain-specific thyroid hormone transporter OATP1C1 are associated with fatigue and depression in hypothyroid patients

(2008) Wendy M. van der Deure et al.   CLINICAL ENDOCRINOLOGY

The effect of genetic variation in the type 1 deiodinase gene on the interindividual variation in serum thyroid hormone levels: an investigation in healthy Danish twins

(2008) Wendy M. van der Deure et al.   CLINICAL ENDOCRINOLOGY

Thr92Ala polymorphism in the type 2 deiodinase is not associated with T4 dose in athyroid patients or patients with Hashimoto thyroiditis

(2008) K. A. Heemstra et al.   CLINICAL ENDOCRINOLOGY

Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling1

(2008) Balázs Gereben et al.   ENDOCRINE REVIEWS

Triiodothyronine Levels in Athyreotic Individuals During Levothyroxine Therapy

(2008) Jacqueline Jonklaas   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Common Variation in Deiodinase 1 GeneDIO1Is Associated with the Relative Levels of Free Thyroxine and Triiodothyronine

(2008) Vijay Panicker et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Free Triiodothyronine Has a Distinct Circadian Rhythm That Is Delayed but Parallels Thyrotropin Levels

(2008) W. Russell et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Type 2 Deiodinase Polymorphism (Threonine 92 Alanine) Predictsl-Thyroxine Dose to Achieve Target Thyrotropin Levels in Thyroidectomized Patients

(2007) Massimo Torlontano et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Psychological wellbeing in patients

(2003) Paul W. Ladenson   CLINICAL ENDOCRINOLOGY