Quantifying factors for the success of stratified medicine

2010 Alzheimer's disease facts and figures

(2010)   Alzheimers & Dementia

Targeting the Mitogen-Activated Protein Kinase Pathway: Physiological Feedback and Drug Response

(2010) C. A. Pratilas et al.   CLINICAL CANCER RESEARCH

Crizotinib inALK-Rearranged Inflammatory Myofibroblastic Tumor

(2010) James E. Butrynski et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

(2010) Eunice L. Kwak et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Path to Personalized Medicine

(2010) Margaret A. Hamburg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter‐Related Infection: 2009 Update by the Infectious Diseases Society of America

(2009) Leonard A. Mermel et al.   CLINICAL INFECTIOUS DISEASES

Predictive Biomarkers in the Development of Oncology Drugs: A Therapeutic Industry Perspective

(2009) BM Fine et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment

(2009) Niklas Mattsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical Trial Designs for Predictive Biomarker Validation: Theoretical Considerations and Practical Challenges

(2009) Sumithra J. Mandrekar et al.   JOURNAL OF CLINICAL ONCOLOGY

Adjuvant Chemotherapy for Non–Small-Cell Lung Cancer: It Does Not Always Fade With Time

(2009) Jean-Yves Douillard   JOURNAL OF CLINICAL ONCOLOGY

Use of CSF biomarkers in Alzheimer’s disease clinical trials

(2009) K. Blennow et al.   Journal of Nutrition Health & Aging

Use of Archived Specimens in Evaluation of Prognostic and Predictive Biomarkers

(2009) R. M. Simon et al.   JNCI-Journal of the National Cancer Institute

A Perspective on Challenges and Issues in Biomarker Development and Drug and Biomarker Codevelopment

(2009) S. E. Taube et al.   JNCI-Journal of the National Cancer Institute

Developing tools for stratified medicine

(2009) Bethan Hughes   NATURE REVIEWS DRUG DISCOVERY

The microeconomics of personalized medicine: today's challenge and tomorrow's promise

(2009) Jerel C. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

Genomic Alterations of Anaplastic Lymphoma Kinase May Sensitize Tumors to Anaplastic Lymphoma Kinase Inhibitors

(2008) U. McDermott et al.   CANCER RESEARCH

The Use of Genomics in Clinical Trial Design

(2008) R. Simon   CLINICAL CANCER RESEARCH

KRAS mutations predict response to EGFR inhibitors

(2008) Mitch Raponi et al.   CURRENT OPINION IN PHARMACOLOGY

Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer

(2008) Rafael G. Amado et al.   JOURNAL OF CLINICAL ONCOLOGY

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE

Using short-term evidence to predict six-month outcomes in clinical trials of signs and symptoms in rheumatoid arthritis

(2008) Richard M. Nixon et al.   PHARMACEUTICAL STATISTICS

Electroencephalography and event-related potentials as biomarkers of mild cognitive impairment and mild Alzheimer’s disease

(2007) Colleen E. Jackson et al.   Alzheimers & Dementia

EGF-receptor targeting with monoclonal antibodies in colorectal carcinomas: rationale for a pharmacogenomic approach

(2007) Fotios Loupakis et al.   PHARMACOGENOMICS