Synthesis of the Pitstop family of clathrin inhibitors

Clathrin Terminal Domain-Ligand Interactions Regulate Sorting of Mannose 6-Phosphate Receptors Mediated by AP-1 and GGA Adaptors

(2014) Wiebke Stahlschmidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of 1,8-Naphthalimides as Clathrin Inhibitors

(2013) Kylie A. MacGregor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pituitary Adenylate Cyclase 1 Receptor Internalization and Endosomal Signaling Mediate the Pituitary Adenylate Cyclase Activating Polypeptide-Induced Increase in Guinea Pig Cardiac Neuron Excitability

(2013) L. A. Merriam et al.   JOURNAL OF NEUROSCIENCE

Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells

(2013) Charlotte M Smith et al.   Molecular Cancer

Target validation using chemical probes

(2013) Mark E Bunnage et al.   Nature Chemical Biology

Crimean–Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway

(2013) Aura R. Garrison et al.   VIROLOGY

Diversity of Clathrin Function: New Tricks for an Old Protein

(2012) Frances M. Brodsky   Annual Review of Cell and Developmental Biology

The First Five Seconds in the Life of a Clathrin-Coated Pit

(2012) Emanuele Cocucci et al.   CELL

Dynamin2, Clathrin, and Lipid Rafts Mediate Endocytosis of the Apical Na/K/2Cl Cotransporter NKCC2 in Thick Ascending Limbs

(2012) Gustavo R. Ares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Internalization of Proprotein Convertase PC7 from Plasma Membrane Is Mediated by a Novel Motif

(2012) Jeroen Declercq et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons

(2012) Jessica W. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of clathrin in mitotic spindle organisation

(2012) S. J. Royle   JOURNAL OF CELL SCIENCE

Bovine Ephemeral Fever Virus Uses a Clathrin-Mediated and Dynamin 2-Dependent Endocytosis Pathway That Requires Rab5 and Rab7 as Well as Microtubules

(2012) C. Y. Cheng et al.   JOURNAL OF VIROLOGY

Caveolae, Fenestrae and Transendothelial Channels Retain PV1 on the Surface of Endothelial Cells

(2012) Eugene Tkachenko et al.   PLoS One

Pitstop 2 Is a Potent Inhibitor of Clathrin-Independent Endocytosis

(2012) Dipannita Dutta et al.   PLoS One

High-Affinity Dkk1 Receptor Kremen1 Is Internalized by Clathrin-Mediated Endocytosis

(2012) Sanjay K. Mishra et al.   PLoS One

Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors

(2012) Callista B. Harper et al.   TRENDS IN CELL BIOLOGY

The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity

(2012) Mark J. Robertson et al.   ACS Medicinal Chemistry Letters

Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition

(2011) Lisa von Kleist et al.   CELL

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functional Analysis of Interaction Sites on the N-Terminal Domain of Clathrin Heavy Chain

(2011) Anna K. Willox et al.   TRAFFIC

Synthesis of 5-arylidene-2-amino-4-azolones and evaluation of their anticancer activity

(2010) Ivanna Subtel’na et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Contribution of Lysine 11-linked Ubiquitination to MIR2-mediated Major Histocompatibility Complex Class I Internalization

(2010) Eiji Goto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability

(2010) Chiou-Hong Lin et al.   JOURNAL OF CELL BIOLOGY

An endophilin-dynamin complex promotes budding of clathrin-coated vesicles during synaptic vesicle recycling

(2010) A. Sundborger et al.   JOURNAL OF CELL SCIENCE

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

FCHo Proteins Are Nucleators of Clathrin-Mediated Endocytosis

(2010) W. M. Henne et al.   SCIENCE

Ionic liquids accelerate access to N-substituted-1,8-naphthalimides

(2010) Kylie A. MacGregor et al.   TETRAHEDRON LETTERS

Ebola virus uses clathrin-mediated endocytosis as an entry pathway

(2010) Suchita Bhattacharyya et al.   VIROLOGY

SnapShot: Endocytic Trafficking

(2009) Marnix Wieffer et al.   CELL

HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes

(2009) Kosuke Miyauchi et al.   CELL

Coordinated Actions of Actin and BAR Proteins Upstream of Dynamin at Endocytic Clathrin-Coated Pits

(2009) Shawn Ferguson et al.   DEVELOPMENTAL CELL

Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation

(2009) Amanda Reider et al.   EMBO JOURNAL

Structure of an Arrestin2-Clathrin Complex Reveals a Novel Clathrin Binding Domain That Modulates Receptor Trafficking

(2009) Dong Soo Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Alkylation of imides using phase transfer catalysts under solvent-free conditions

(2009) Jolanta Jaśkowska et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Tickets to ride: selecting cargo for clathrin-regulated internalization

(2009) Linton M. Traub   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct Dynamics of Endocytic Clathrin-Coated Pits and Coated Plaques

(2009) Saveez Saffarian et al.   PLOS BIOLOGY

Crimean-Congo hemorrhagic fever virus entry and replication is clathrin-, pH- and cholesterol-dependent

(2008) M. Simon et al.   JOURNAL OF GENERAL VIROLOGY

Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality

(2008) K Sasai et al.   ONCOGENE

Three-component one-pot synthetic route to 2-amino-5-alkylidene-thiazol-4-ones

(2008) Marko Anderluh et al.   TETRAHEDRON