Time-resolved fluorescence ligand binding for G protein–coupled receptors

Novel fluorescent antagonist as a molecular probe in A3 adenosine receptor binding assays using flow cytometry

(2012) Eszter Kozma et al.   BIOCHEMICAL PHARMACOLOGY

A novel fluorescent histamine H1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands

(2012) Rachel H Rose et al.   BRITISH JOURNAL OF PHARMACOLOGY

Apo-Ghrelin Receptor Forms Heteromers with DRD2 in Hypothalamic Neurons and Is Essential for Anorexigenic Effects of DRD2 Agonism

(2012) Andras Kern et al.   NEURON

Development of Probes for Cellular Functions Using Fluorescent Proteins and Fluorescence Resonance Energy Transfer

(2011) Atsushi Miyawaki   Annual Review of Biochemistry

FLIM FRET Technology for Drug Discovery: Automated Multiwell-Plate High-Content Analysis, Multiplexed Readouts and Application in Situ

(2011) Sunil Kumar et al.   CHEMPHYSCHEM

Synthesis and Characterization of High-Affinity 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene-Labeled Fluorescent Ligands for Human β-Adrenoceptors

(2011) Jillian G. Baker et al.   JOURNAL OF MEDICINAL CHEMISTRY

Octadentate Cages of Tb(III) 2-Hydroxyisophthalamides: A New Standard for Luminescent Lanthanide Labels

(2011) Jide Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

(2011) Sebastian Börner et al.   Nature Protocols

Trends in the exploitation of novel drug targets

(2011) Mathias Rask-Andersen et al.   NATURE REVIEWS DRUG DISCOVERY

Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a

(2010) Jean-Philippe Leyris et al.   ANALYTICAL BIOCHEMISTRY

Novel Alexa Fluor-488 labeled antagonist of the A2A adenosine receptor: Application to a fluorescence polarization-based receptor binding assay

(2010) Miklós Kecskés et al.   BIOCHEMICAL PHARMACOLOGY

Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and ‘cannabinoid-like’ receptors in small arteries

(2010) CJ Daly et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fluorescence polarization assays in small molecule screening

(2010) Wendy A Lea et al.   Expert Opinion on Drug Discovery

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

(2010) Laura Albizu et al.   Nature Chemical Biology

Spin Quantum Bit with Ferromagnetic Contacts for Circuit QED

(2010) Audrey Cottet et al.   PHYSICAL REVIEW LETTERS

Class A GPCR heterodimers: evidence from binding studies

(2010) Nigel J.M. Birdsall   TRENDS IN PHARMACOLOGICAL SCIENCES

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Homogeneous G Protein-Coupled Receptor Ligand Binding Assay Based on Time-Resolved Fluorescence Resonance Energy Transfer

(2008) Liaoyuan A. Hu et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Fluorophore Labeling Enables Imaging and Evaluation of Specific CXCR4−Ligand Interaction at the Cell Membrane for Fluorescence-Based Screening

(2008) Wataru Nomura et al.   BIOCONJUGATE CHEMISTRY

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization

(2008) Damien Maurel et al.   NATURE METHODS

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular recognition of parathyroid hormone by its G protein-coupled receptor

(2008) Augen A. Pioszak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered Selectivity of Parathyroid Hormone (PTH) and PTH-Related Protein (PTHrP) for Distinct Conformations of the PTH/PTHrP Receptor

(2007) Thomas Dean et al.   MOLECULAR ENDOCRINOLOGY