Force dependency of biochemical reactions measured by single-molecule force-clamp spectroscopy

Protein Folding Drives Disulfide Formation

(2012) Pallav Kosuri et al.   CELL

AFM-Based Force-Clamp Monitors Lipid Bilayer Failure Kinetics

(2012) Lorena Redondo-Morata et al.   LANGMUIR

A backbone lever-arm effect enhances polymer mechanochemistry

(2012) Hope M. Klukovich et al.   Nature Chemistry

Rate limit of protein elastic response is tether dependent

(2012) R. Berkovich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Quantification of the Attempt Frequency Determining the Mechanical Unfolding of Ubiquitin Protein

(2011) Ionel Popa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of External Force on Properties and Reactivity of Disulfide Bonds

(2011) Maria Francesca Iozzi et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Contrasting the Individual Reactive Pathways in Protein Unfolding and Disulfide Bond Reduction Observed within a Single Protein

(2011) Sergi Garcia-Manyes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic Measurements on Single-Molecule Disulfide Bond Cleavage

(2011) Jian Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Covalent Ferric−Thiolate Bonds Exhibit Surprisingly Low Mechanical Stability

(2011) Peng Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct observation of disulfide isomerization in a single protein

(2011) Jorge Alegre-Cebollada et al.   Nature Chemistry

Single-molecule paleoenzymology probes the chemistry of resurrected enzymes

(2011) Raul Perez-Jimenez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Collapse Dynamics of Single Proteins Extended by Force

(2010) Ronen Berkovich et al.   BIOPHYSICAL JOURNAL

Structural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet Twisting

(2010) Isolde Le Trong et al.   CELL

Isopeptide Bonds Block the Mechanical Extension of Pili in PathogenicStreptococcus pyogenes

(2010) Jorge Alegre-Cebollada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atomistic Evidence of How Force Dynamically Regulates Thiol/Disulfide Exchange

(2010) Wenjin Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Application of HaloTag Protein to Covalent Immobilization of Recombinant Proteins for Single Molecule Force Spectroscopy

(2010) Yukinori Taniguchi et al.   LANGMUIR

A mechanically stabilized receptor–ligand flex-bond important in the vasculature

(2010) Jongseong Kim et al.   NATURE

Thiol-based, site-specific and covalent immobilization of biomolecules for single-molecule experiments

(2010) Julia L Zimmermann et al.   Nature Protocols

Probing static disorder in Arrhenius kinetics by single-molecule force spectroscopy

(2010) T.-L. Kuo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical Characterization of Protein L in the Low-Force Regime by Electromagnetic Tweezers/Evanescent Nanometry

(2009) Ruchuan Liu et al.   BIOPHYSICAL JOURNAL

Force-activated reactivity switch in a bimolecular chemical reaction

(2009) Sergi Garcia-Manyes et al.   Nature Chemistry

Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy

(2009) Raul Perez-Jimenez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Osmolyte-induced separation of the mechanical folding phases of ubiquitin

(2009) S. Garcia-Manyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct observation of an ensemble of stable collapsed states in the mechanical folding of ubiquitin

(2009) S. Garcia-Manyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Observation of Markovian Behavior of the Mechanical Unfolding of Individual Proteins

(2008) Yi Cao et al.   BIOPHYSICAL JOURNAL

Single-Molecule Force Spectroscopy Measurements of Bond Elongation during a Bimolecular Reaction

(2008) Sri Rama Koti Ainavarapu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dwell Time Analysis of a Single-Molecule Mechanochemical Reaction†

(2007) Robert Szoszkiewicz et al.   LANGMUIR