PIEZO2 is required for mechanotransduction in human stem cell–derived touch receptors

Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5

(2014) Margaret J. McMillin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Merkel Cells Transduce and Encode Tactile Stimuli to Drive Aβ-Afferent Impulses

(2014) Ryo Ikeda et al.   CELL

Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research

(2014) Gareth T Young et al.   MOLECULAR THERAPY

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors

(2014) Srdjan Maksimovic et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

(2014) Kate Poole et al.   Nature Communications

Cas9 as a versatile tool for engineering biology

(2013) Prashant Mali et al.   NATURE METHODS

The Sensory Neurons of Touch

(2013) Victoria E. Abraira et al.   NEURON

Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

(2013) Yingsha Zhang et al.   NEURON

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

(2013) B. Coste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

(2012) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

The Transcription Factor c-Maf Controls Touch Receptor Development and Function

(2012) H. Wende et al.   SCIENCE

Molecular interactions underlying the specification of sensory neurons

(2012) Francois Lallemend et al.   TRENDS IN NEUROSCIENCES

Genetic engineering of human pluripotent cells using TALE nucleases

(2011) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man

(2011) Matthias Heidenreich et al.   NATURE NEUROSCIENCE

Single-cell analysis of sodium channel expression in dorsal root ganglion neurons

(2010) Cojen Ho et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

CHD7 cooperates with PBAF to control multipotent neural crest formation

(2010) Ruchi Bajpai et al.   NATURE

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Generation of Transgene-Free Lung Disease-Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette

(2010) Aba Somers et al.   STEM CELLS

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development

(2009) Stefan G Lechner et al.   EMBO JOURNAL

Molecular Identification of Rapidly Adapting Mechanoreceptors and Their Developmental Dependence on Ret Signaling

(2009) Wenqin Luo et al.   NEURON

Low-Threshold Mechanoreceptor Subtypes Selectively Express MafA and Are Specified by Ret Signaling

(2009) Steeve Bourane et al.   NEURON

A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells

(2008) Nimet Maherali et al.   Cell Stem Cell

Differentiation of neural lineage cells from human pluripotent stem cells

(2008) P SCHWARTZ et al.   METHODS

A central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programs

(2008) Yunfu Sun et al.   NATURE NEUROSCIENCE